Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
skip to main content
10.1007/978-3-031-16452-1_47guideproceedingsArticle/Chapter ViewAbstractPublication PagesConference Proceedingsacm-pubtype
Article

CRISP - Reliable Uncertainty Estimation for Medical Image Segmentation

Published: 18 September 2022 Publication History

Abstract

Accurate uncertainty estimation is a critical need for the medical imaging community. A variety of methods have been proposed, all direct extensions of classification uncertainty estimations techniques. The independent pixel-wise uncertainty estimates, often based on the probabilistic interpretation of neural networks, do not take into account anatomical prior knowledge and consequently provide sub-optimal results to many segmentation tasks. For this reason, we propose CRISP a ContRastive Image Segmentation for uncertainty Prediction method. At its core, CRISP implements a contrastive method to learn a joint latent space which encodes a distribution of valid segmentations and their corresponding images. We use this joint latent space to compare predictions to thousands of latent vectors and provide anatomically consistent uncertainty maps. Comprehensive studies performed on four medical image databases involving different modalities and organs underlines the superiority of our method compared to state-of-the-art approaches. Code is available at: https://github.com/ThierryJudge/CRISP-uncertainty.

References

[1]
Baumgartner, C.F., et al.: PHiSeg: capturing uncertainty in medical image segmentation. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11765, pp. 119–127. Springer, Cham (2019).
[2]
Corbière, C., Thome, N., Bar-Hen, A., Cord, M., Pérez, P.: Addressing failure prediction by learning model confidence. In: Advances in Neural Information Processing Systems, vol. 32, pp. 2902–2913. Curran Associates, Inc. (2019)
[3]
Degerli, A., et al.: Early detection of myocardial infarction in low-quality echocardiography. IEEE Access 9, 34442–34453 (2021)
[4]
DeVries, T., Taylor, G.W.: Learning confidence for out-of-distribution detection in neural networks. arXiv preprint arXiv:1802.04865 (2018)
[5]
Gal, Y., Ghahramani, Z.: Bayesian convolutional neural networks with Bernoulli approximate variational inference. arXiv preprint arXiv:1506.02158 (2015)
[6]
Gal, Y., Ghahramani, Z.: Dropout as a Bayesian approximation: representing model uncertainty in deep learning. In: Proceedings of the 33rd International Conference on International Conference on Machine Learning (ICML’16), vol. 48, pp. 1050–1059. JMLR.org (2016)
[7]
Guo, C., Pleiss, G., Sun, Y., Weinberger, K.Q.: On calibration of modern neural networks. In: Precup, D., Teh, Y.W. (eds.) Proceedings of the 34th International Conference on Machine Learning. Proceedings of Machine Learning Research, 06–11 August 2017, vol. 70, pp. 1321–1330. PMLR (2017)
[8]
Jaeger S, Candemir S, Antani S, Wáng YXJ, Lu PX, and Thoma G Two public chest x-ray datasets for computer-aided screening of pulmonary diseases Quan. Imaging Med. Surg. 2014 4 475
[9]
Jungo, A., Reyes, M.: Assessing reliability and challenges of uncertainty estimations for medical image segmentation. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11765, pp. 48–56. Springer, Cham (2019).
[10]
Kendall, A., Gal, Y.: What uncertainties do we need in bayesian deep learning for computer vision? In: Guyon, I., et al. (eds.) Advances in Neural Information Processing Systems, vol. 30, pp. 5574–5584. Curran Associates, Inc. (2017)
[11]
Kendall, A., Gal, Y.: What uncertainties do we need in bayesian deep learning for computer vision? In: Guyon, I., et al. (eds.) Advances in Neural Information Processing Systems, vol. 30. Curran Associates, Inc. (2017)
[12]
Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. In: Bengio, Y., LeCun, Y. (eds.) Proceedings of the 3rd International Conference on Learning Representations, ICLR 2015, San Diego, 7–9 May 2015, Conference Track (2015)
[13]
Kohl, S., et al.: A probabilistic u-net for segmentation of ambiguous images. In: Advances in Neural Information Processing Systems, vol. 31. Curran Associates, Inc. (2018)
[14]
Lakshminarayanan, B., Pritzel, A., Blundell, C.: Simple and scalable predictive uncertainty estimation using deep ensembles. In: Guyon, I., et al. (eds.) Advances in Neural Information Processing Systems, vol. 30. Curran Associates, Inc. (2017)
[15]
Leclerc S et al. Deep learning for segmentation using an open large-scale dataset in 2d echocardiography IEEE Trans. Med. Imaging 2019 38 9 2198-2210
[16]
Mardia, K.V., Jupp, P.E.: Directional Statistics. Wiley (1999)
[17]
Oktay O et al. Anatomically constrained neural networks (ACNNS): application to cardiac image enhancement and segmentation IEEE Trans. Med. Imaging 2018 37 2 384-395
[18]
Painchaud N, Skandarani Y, Judge T, Bernard O, Lalande A, and Jodoin PM Cardiac segmentation with strong anatomical guarantees IEEE Trans. Med. Imaging 2020 39 11 3703-3713
[19]
Pakdaman Naeini, M., Cooper, G., Hauskrecht, M.: Obtaining well calibrated probabilities using bayesian binning. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 29, no. 1 (2015)
[20]
Paszke, A., Chaurasia, A., Kim, S., Culurciello, E.: Enet: a deep neural network architecture for real-time semantic segmentation. arXiv preprint arXiv:1606.02147 (2016)
[21]
Radford, A., et al.: Learning transferable visual models from natural language supervision. arXiv preprint arXiv:2103.00020 (2021)
[22]
Settles, B.: Active learning literature survey. In: Computer Sciences Technical Report 1648. University of Wisconsin-Madison (2009)
[23]
Shiraishi J et al. Development of a digital image database for chest radiographs with and without a lung nodule: receiver operating characteristic analysis of radiologists’ detection of pulmonary nodules Am. J. Roentgenol. 2000 174 71-74
[24]
Taylor CC Automatic bandwidth selection for circular density estimation Comput. Statist. Data Anal. 2008 52 7 3493-3500
[25]
Zotti, C., Humbert, O., Lalande, A., Jodoin, P.M.: Gridnet with automatic shape prior registration for automatic MRI cardiac segmentation. In: MICCAI - ACDC Challenge (2017)

Cited By

View all
  • (2023)Asymmetric Contour Uncertainty Estimation for Medical Image SegmentationMedical Image Computing and Computer Assisted Intervention – MICCAI 202310.1007/978-3-031-43898-1_21(210-220)Online publication date: 8-Oct-2023

Recommendations

Comments

Information & Contributors

Information

Published In

cover image Guide Proceedings
Medical Image Computing and Computer Assisted Intervention – MICCAI 2022: 25th International Conference, Singapore, September 18–22, 2022, Proceedings, Part VIII
Sep 2022
773 pages
ISBN:978-3-031-16451-4
DOI:10.1007/978-3-031-16452-1
  • Editors:
  • Linwei Wang,
  • Qi Dou,
  • P. Thomas Fletcher,
  • Stefanie Speidel,
  • Shuo Li

Publisher

Springer-Verlag

Berlin, Heidelberg

Publication History

Published: 18 September 2022

Author Tags

  1. Medical imaging
  2. Segmentation
  3. Uncertainty
  4. Deep learning

Qualifiers

  • Article

Contributors

Other Metrics

Bibliometrics & Citations

Bibliometrics

Article Metrics

  • Downloads (Last 12 months)0
  • Downloads (Last 6 weeks)0
Reflects downloads up to 10 Nov 2024

Other Metrics

Citations

Cited By

View all
  • (2023)Asymmetric Contour Uncertainty Estimation for Medical Image SegmentationMedical Image Computing and Computer Assisted Intervention – MICCAI 202310.1007/978-3-031-43898-1_21(210-220)Online publication date: 8-Oct-2023

View Options

View options

Get Access

Login options

Media

Figures

Other

Tables

Share

Share

Share this Publication link

Share on social media