Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
skip to main content
10.1007/978-3-031-21014-3_12guideproceedingsArticle/Chapter ViewAbstractPublication PagesConference Proceedingsacm-pubtype
Article

AutoMO-Mixer: An Automated Multi-objective Mixer Model for Balanced, Safe and Robust Prediction in Medicine

Published: 16 December 2022 Publication History

Abstract

Accurately identifying patient’s status through medical images plays an important role in diagnosis and treatment. Artificial intelligence (AI), especially the deep learning, has achieved great success in many fields. However, more reliable AI model is needed in image guided diagnosis and therapy. To achieve this goal, developing a balanced, safe and robust model with a unified framework is desirable. In this study, a new unified model termed as automated multi-objective Mixer (AutoMO-Mixer) model was developed, which utilized a recent developed multiple layer perceptron Mixer (MLP-Mixer) as base. To build a balanced model, sensitivity and specificity were considered as the objective functions simultaneously in training stage. Meanwhile, a new evidential reasoning based on entropy was developed to achieve a safe and robust model in testing stage. The experiment on an optical coherence tomography dataset demonstrated that AutoMO-Mixer can obtain safer, more balanced, and robust results compared with MLP-Mixer and other available models.

References

[1]
Zhang, Y., An, M.: Deep learning-and transfer learning-based super resolution reconstruction from single medical image. J. Healthc. Eng. 2017 (2017)
[2]
Shen D, Wu G, and Suk HI Deep learning in medical image analysis Annu. Rev. Biomed. Eng. 2017 19 221-248
[3]
Kendall, A., Gal, Y.: What uncertainties do we need in Bayesian deep learning for computer vision? In: Advances in Neural Information Processing Systems, vol. 30 (2017)
[4]
Huynh E et al. CT-based radiomic analysis of stereotactic body radiation therapy patients with lung cancer Radiother. Oncol. 2016 120 2 258-266
[5]
Vallières M, Freeman CR, Skamene SR, and El Naqa I A radiomics model from joint FDG-PET and MRI texture features for the prediction of lung metastases in soft-tissue sarcomas of the extremities Phys. Med. Biol. 2015 60 14 5471
[6]
Błaszczyński J, Deckert M, Stefanowski J, and Wilk S Szczuka M, Kryszkiewicz M, Ramanna S, Jensen R, and Hu Q Integrating selective pre-processing of imbalanced data with Ivotes ensemble Rough Sets and Current Trends in Computing 2010 Heidelberg Springer 148-157
[7]
Chen H, Deng T, Du T, Chen B, Skibniewski MJ, and Zhang L An RF and LSSVM-NSGA-II method for the multi-objective optimization of high-performance concrete durability Cem. Concr. Compos. 2022 129 104446
[8]
Bagheri-Esfeh H and Dehghan MR Multi-objective optimization of setpoint temperature of thermostats in residential buildings Energ. Build. 2022 261 111955
[9]
Ayhan, M.S., Berens, P.: Test-time data augmentation for estimation of heteroscedastic aleatoric uncertainty in deep neural networks (2018)
[10]
Dohopolski M, Chen L, Sher D, and Wang J Predicting lymph node metastasis in patients with oropharyngeal cancer by using a convolutional neural network with associated epistemic and aleatoric uncertainty Phys. Med. Biol. 2020 65 22 225002
[11]
Uwimana, A., Senanayake, R.: Out of distribution detection and adversarial attacks on deep neural networks for robust medical image analysis. arXiv preprint arXiv:2107.04882 (2021)
[12]
Liang, S., Li, Y., Srikant, R.: Enhancing the reliability of out-of-distribution image detection in neural networks. arXiv preprint arXiv:1706.02690 (2017)
[13]
Ge, Z., Wang, X.: Evaluation of various open-set medical imaging tasks with deep neural networks. arXiv preprint arXiv:2110.10888 (2021)
[14]
Apostolidis KD and Papakostas GA A survey on adversarial deep learning robustness in medical image analysis Electronics 2021 10 17 2132
[15]
Paschali M, Conjeti S, Navarro F, and Navab N Frangi AF, Schnabel JA, Davatzikos C, Alberola-López C, and Fichtinger G Generalizability vs. robustness: investigating medical imaging networks using adversarial examples Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 2018 Cham Springer 493-501
[16]
Mangaokar, N., Pu, J., Bhattacharya, P., Reddy, C.K., Viswanath, B.: Jekyll: attacking medical image diagnostics using deep generative models. In: 2020 IEEE European Symposium on Security and Privacy (EuroS &P), pp. 139–157. IEEE (2020)
[17]
Xu M, Zhang T, Li Z, Liu M, and Zhang D Towards evaluating the robustness of deep diagnostic models by adversarial attack Med. Image Anal. 2021 69 101977
[18]
Yun, S., Han, D., Oh, S.J., Chun, S., Choe, J., Yoo, Y.: CutMix: regularization strategy to train strong classifiers with localizable features. In: Proceedings of the IEEE/CVF International Conference on Computer Vision, pp. 6023–6032 (2019)
[19]
Tolstikhin, I.O., et al.: MLP-mixer: an all-MLP architecture for vision. In: Advances in Neural Information Processing Systems, vol. 34 (2021)
[20]
Zhou Z et al. Multi-objective radiomics model for predicting distant failure in lung SBRT Phys. Med. Biol. 2017 62 11 4460
[21]
Pelikan M Pelikan M Bayesian optimization algorithm Hierarchical Bayesian Optimization Algorithm 2005 Heidelberg Springer
[22]
Yang JB and Xu DL On the evidential reasoning algorithm for multiple attribute decision analysis under uncertainty IEEE Trans. Syst. Man Cybern. Part A Syst. Hum. 2002 32 3 289-304
[23]
Wang YM, Yang JB, and Xu DL Environmental impact assessment using the evidential reasoning approach Eur. J. Oper. Res. 2006 174 3 1885-1913
[24]
Goodfellow, I.J., Shlens, J., Szegedy, C.: Explaining and harnessing adversarial examples. arXiv preprint arXiv:1412.6572 (2014)

Index Terms

  1. AutoMO-Mixer: An Automated Multi-objective Mixer Model for Balanced, Safe and Robust Prediction in Medicine
        Index terms have been assigned to the content through auto-classification.

        Recommendations

        Comments

        Information & Contributors

        Information

        Published In

        cover image Guide Proceedings
        Machine Learning in Medical Imaging: 13th International Workshop, MLMI 2022, Held in Conjunction with MICCAI 2022, Singapore, September 18, 2022, Proceedings
        Sep 2022
        490 pages
        ISBN:978-3-031-21013-6
        DOI:10.1007/978-3-031-21014-3
        • Editors:
        • Chunfeng Lian,
        • Xiaohuan Cao,
        • Islem Rekik,
        • Xuanang Xu,
        • Zhiming Cui

        Publisher

        Springer-Verlag

        Berlin, Heidelberg

        Publication History

        Published: 16 December 2022

        Author Tags

        1. Image guided diagnosis and therapy
        2. Reliable artificial intelligence
        3. Balance
        4. Safe
        5. Robustness

        Qualifiers

        • Article

        Contributors

        Other Metrics

        Bibliometrics & Citations

        Bibliometrics

        Article Metrics

        • 0
          Total Citations
        • 0
          Total Downloads
        • Downloads (Last 12 months)0
        • Downloads (Last 6 weeks)0
        Reflects downloads up to 18 Feb 2025

        Other Metrics

        Citations

        View Options

        View options

        Figures

        Tables

        Media

        Share

        Share

        Share this Publication link

        Share on social media