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Multiple organ-specific cancers classification from PET/CT images using deep learning

Published: 01 May 2022 Publication History

Abstract

As the number of cancer cases increases and the popularity of positron emission tomography/computed tomography (PET/CT), an automated cancer screening system that can assist radiologists is desired. The existing methods based on PET/CT images are mostly limited to one specific organ. In this paper, a method based on deep learning is proposed that can classify multiple organ-specific cancer to assist radiologists. In the classification model, we introduce a modality fusion module to fuse PET images, CT images, and the segmentation result of multi-organs. The segmentation result of organs is used as the attention map which can force the network to learn organ-related features from the whole-body PET/CT image. Since the low-dose computed tomography (LDCT) images are widely used in PET/CT, a grayscale transformation strategy and a double-level V-net are proposed to segment multiple organs in LDCT. The proposed grayscale transformation strategy solves insufficient annotated data, and the double-level V-net strengthens the context information of images. The proposed method can classify PET/CT images into six screening classes (health, esophageal cancer, gastric cancer, liver cancer, pancreatic cancer, and lung cancer). The experimental results demonstrate that the F-score of the classifier reaches 82.3%, indicating that it can assists radiologists in screening cancers.

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  • (2023)Pulmonary fissure segmentation in CT images based on ODoS filter and shape featuresMultimedia Tools and Applications10.1007/s11042-023-14931-y82:22(34959-34980)Online publication date: 1-Sep-2023
  • (2022)CTSC-Net: an effectual CT slice classification network to categorize organ and non-organ slices from a 3-D CT imageNeural Computing and Applications10.1007/s00521-022-07701-834:24(22141-22156)Online publication date: 1-Dec-2022

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          Published In

          cover image Multimedia Tools and Applications
          Multimedia Tools and Applications  Volume 81, Issue 12
          May 2022
          1382 pages

          Publisher

          Kluwer Academic Publishers

          United States

          Publication History

          Published: 01 May 2022
          Accepted: 04 January 2022
          Revision received: 30 May 2021
          Received: 04 February 2021

          Author Tags

          1. Computer-aided diagnosis
          2. Organ-specific cancer
          3. Deep learning
          4. Convolutional neural network
          5. Multi-organ segmentation
          6. PET/CT

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          • (2023)Pulmonary fissure segmentation in CT images based on ODoS filter and shape featuresMultimedia Tools and Applications10.1007/s11042-023-14931-y82:22(34959-34980)Online publication date: 1-Sep-2023
          • (2022)CTSC-Net: an effectual CT slice classification network to categorize organ and non-organ slices from a 3-D CT imageNeural Computing and Applications10.1007/s00521-022-07701-834:24(22141-22156)Online publication date: 1-Dec-2022

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