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An epidemiology-based model for the operational allocation of COVID-19 vaccines: : A case study of Thailand

Published: 01 May 2022 Publication History

Highlights

An SIQRV model is integrated with the COVID-19 Vaccine Allocation Problem (CVAP).
With limited vaccine supply, epicenter-based strategies tend to underperform.
Demographics and vaccine efficacy greatly affect the potency of vaccine allocation.
Early vaccination could significantly reduce the number of infected individuals.
Societal cooperation plays a crucial role in controlling the spread of COVID-19.

Abstract

This paper addresses a framework for the operational allocation and administration of COVID-19 vaccines in Thailand, based on both COVID-19 transmission dynamics and other vital operational restrictions that might affect the effectiveness of vaccination strategies in the early stage of vaccine rollout. In this framework, the SIQRV model is first developed and later combined with the COVID-19 Vaccine Allocation Problem (CVAP) to determine the optimal allocation/administration strategies that minimize total weighted strain on the whole healthcare system. According to Thailand’s second pandemic wave data (17th January 2021, to 15th February 2021), we find that the epicenter-based strategy is surprisingly the worst allocation strategy, due largely to the negligence of provincial demographics, vaccine efficacy, and overall transmission dynamics that lead to higher number of infectious individuals. We also find that early vaccination seems to significantly contribute to the reduction in the number of infectious individuals, whose effects tend to increase with more vaccine supply. With these insights, healthcare policy-makers should therefore focus not only on the procurement of COVID-19 vaccines at strategic levels but also on the allocation and administration of such vaccines at operational levels for the best of their limited vaccine supply.

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Cited By

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  • (2023)A relax-and-fix Pareto-based algorithm for a bi-objective vaccine distribution network considering a mix-and-match strategy in pandemicsApplied Soft Computing10.1016/j.asoc.2022.109862132:COnline publication date: 1-Jan-2023

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          Published In

          cover image Computers and Industrial Engineering
          Computers and Industrial Engineering  Volume 167, Issue C
          May 2022
          696 pages

          Publisher

          Pergamon Press, Inc.

          United States

          Publication History

          Published: 01 May 2022

          Author Tags

          1. COVID-19
          2. Epidemiological model
          3. Pandemic
          4. Vaccine allocation
          5. Vaccine administration

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          • (2023)A relax-and-fix Pareto-based algorithm for a bi-objective vaccine distribution network considering a mix-and-match strategy in pandemicsApplied Soft Computing10.1016/j.asoc.2022.109862132:COnline publication date: 1-Jan-2023

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