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Pulmonary Nodule Detection Based on ISODATA-Improved Faster RCNN and 3D-CNN with Focal Loss

Published: 17 April 2020 Publication History

Abstract

The early diagnosis of pulmonary cancer can significantly improve the survival rate of patients, where pulmonary nodules detection in computed tomography images plays an important role. In this article, we propose a novel pulmonary nodule detection system based on convolutional neural networks (CNN). Our system consists of two stages, pulmonary nodule candidate detection and false positive reduction. For candidate detection, we introduce Iterative Self-Organizing Data Analysis Techniques Algorithm (ISODATA) to Faster Region-based Convolutional Neural Network (Faster R-CNN) model. For false positive reduction, a three-dimensional convolutional neural network (3D-CNN) is employed to completely utilize the three-dimensional nature of CT images. In this network, Focal Loss is used to solve the class imbalance problem in this task. Experiments were conducted on LUNA16 dataset. The results show the preferable performance of the proposed system and the effectiveness of using ISODATA and Focal loss in pulmonary nodule detection is proved.

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Published In

cover image ACM Transactions on Multimedia Computing, Communications, and Applications
ACM Transactions on Multimedia Computing, Communications, and Applications  Volume 16, Issue 1s
Special Issue on Multimodal Machine Learning for Human Behavior Analysis and Special Issue on Computational Intelligence for Biomedical Data and Imaging
January 2020
376 pages
ISSN:1551-6857
EISSN:1551-6865
DOI:10.1145/3388236
Issue’s Table of Contents
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Association for Computing Machinery

New York, NY, United States

Publication History

Published: 17 April 2020
Accepted: 01 October 2019
Revised: 01 August 2019
Received: 01 June 2019
Published in TOMM Volume 16, Issue 1s

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  1. Datasets
  2. gaze detection
  3. neural networks
  4. text tagging

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  • Research-article
  • Research
  • Refereed

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  • Project of National Engineering Laboratory for Internet Medical System and Application
  • National Natural Science Foundation of China

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Cited By

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  • (2023)A survey and taxonomy of 2.5D approaches for lung segmentation and nodule detection in CT imagesComputers in Biology and Medicine10.1016/j.compbiomed.2023.107437165(107437)Online publication date: Oct-2023
  • (2022)DATA-CENTRIC DEEP LEARNING METHOD FOR PULMONARY NODULE DETECTIONJournal of Computer Science and Cybernetics10.15625/1813-9663/38/3/1722038:3(229-243)Online publication date: 22-Sep-2022
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  • (2022)Power Load Curve Clustering based on ISODATA2022 IEEE 7th International Conference on Smart Cloud (SmartCloud)10.1109/SmartCloud55982.2022.00022(104-108)Online publication date: Oct-2022
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  • (2021)On Focal Loss for Class-Posterior Probability Estimation: A Theoretical Perspective2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)10.1109/CVPR46437.2021.00516(5198-5207)Online publication date: Jun-2021
  • (2021)Pulmonary Nodule Detection Based on Faster R-CNN With Adaptive Anchor BoxIEEE Access10.1109/ACCESS.2021.31289429(154740-154751)Online publication date: 2021

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