Electrospun poly(L-lactide-co-ε-caprolactone)/polyethylene oxide/hydroxyapaite nanofibrous membrane for guided bone regeneration
Abstract
A series of poly(L-lactide-co-ε-caprolactone)/polyethylene oxide/hydroxyapaite (PLCL/PEO/HA) composite fibrous membranes were prepared by elecrospinning technology for guided bone regeneration. The morphology, water permeability and mechanical properties of the membranes were investigated. The HA nanocrystals can be well distributed in the PLCL/PEO matrix. And the diameter of composite nanofiber is larger than that of pure PLCL. The fibers with uniform size and large diameter were obtained when the contents of PEO and HA were 0.4% and 0.03%, respectively. In this condition, the obtained membrane presents the best water permeability. Furthermore, the nanofibrous membrane with largest tensile strength was obtained when the contents of PEO and HA were 0.5% and 0.03%, respectively.
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Index Terms
- Electrospun poly(L-lactide-co-ε-caprolactone)/polyethylene oxide/hydroxyapaite nanofibrous membrane for guided bone regeneration
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Hindawi Limited
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Publication History
Accepted: 25 March 2010
Published: 01 January 2010
Revised: 22 November 2009
Received: 28 September 2009
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