Template method to improve brain segmentation from inhomogeneous brain magnetic resonance images at high fields
Authors: 
Marcelo A. Castro, Jianhua Yao, Yuxi Pang, Eva Bake, John Butman, David ThomassonAuthors Info & Claims
Marcelo A. Castro, Jianhua Yao, Yuxi Pang, Eva Bake, John Butman, David ThomassonAuthors Info & ClaimsPages 73 - 76
Abstract
Magnetic resonance imaging of the brain at high fields (e.g. 3T) provides high resolution and high signal to noise ratio images suitable for a wide range of clinical applications. However, radiofrequency (or B1) inhomogeneity increases with the magnetic field and produces undesired intensity variations responsible for inaccuracies in quantitative analyses. A method to perform brain segmentation using T1 maps whose inhomogeneity was corrected using previously acquired B1 maps is described. A library of B1 maps was created and a method to compensate the T1 inhomogeneity using a B1 map from another subject (template) was developed. The performance of the template-based method was evaluated in 19 healthy volunteers. Our method produced significantly better segmentations than the retrospective N3 method and the one without B1 inhomogeneity correction.
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Published In
April 2010
1438 pages
ISBN:9781424441259
Publisher
IEEE Press
Publication History
Published: 14 April 2010
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