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- research-articleJanuary 2022
Prediction and identification of epitopes in the Echinococcus multilocularis thrombospondin 3 antigen
- Ming-Quan Pang,
- Yue-Qing Lu,
- Feng Tang,
- Hai-Jiu Wang,
- Ying Zhou,
- Li Ren,
- Run-Le Li,
- Hu Zhou,
- Chen-Fei Wan,
- Chuan-Chuan Liu,
- Dawa Luosang,
- Cairang Yangdan,
- Hai-Ning Fan
Technology and Health Care (TAHC), Volume 30, Issue 4Pages 799–814https://doi.org/10.3233/THC-212983BACKGROUND:Alveolar echinococcosis is an epidemic disease caused by the parasitism of Echinococcus multilocularis (Em) larvae in the intermediate or final host.
OBJECTIVE:To identify and ...
- short-paperAugust 2015
Predicting candidate epitopes on Ebolaviruse for possible vaccine development
ASONAM '15: Proceedings of the 2015 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining 2015Pages 1083–1088https://doi.org/10.1145/2808797.2809370Zaire ebolavirus a member of family Filoviridae is the cause of hemorrhagic fever. Due to lack of appropriate anti-viral or vaccine, this disease is very lethal. In this study we tried to find epitopes for superficial glycoprotein of Zaire ebolavirus (...
- research-articleSeptember 2014
The interplay of sequence conservation and T cell immune recognition
- Anne Bresciani,
- Jason Greenbaum,
- Cecilia S. Lindestam Arlehamn,
- Alessandro Sette,
- Morten Nielsen,
- Bjoern Peters
BCB '14: Proceedings of the 5th ACM Conference on Bioinformatics, Computational Biology, and Health InformaticsPages 739–743https://doi.org/10.1145/2649387.2660843Predicting which peptides can elicit a T cell response (i.e. are immunogenic) is of great importance for many immunological studies. While it is clear that MHC binding is a necessary requirement for peptide immunogenicity, other variables exist that are ...
- tutorialSeptember 2013
Defining Functional Redundancy of Epitope Data as Potential Antigenic Cross-Reactivity
BCB'13: Proceedings of the International Conference on Bioinformatics, Computational Biology and Biomedical InformaticsPages 851–852https://doi.org/10.1145/2506583.2517168In assembling epitope datasets (e.g., to develop and benchmark epitope-prediction tools), sequence redundancy among epitopes must be considered to avoid misleading results that reflect overrepresentation of functionally similar epitopes. However, ...
- ArticleJuly 2009
MHC: Peptide Analysis: Implications on the Immunogenicity of Hantaviruses' N protein
BSB '09: Proceedings of the 4th Brazilian Symposium on Bioinformatics: Advances in Bioinformatics and Computational BiologyPages 160–163https://doi.org/10.1007/978-3-642-03223-3_17Hantaviruses, members of the <em>Bunyaviridae</em> family, are enveloped negative-stranded RNA viruses with tripartite genomes --- S, M and L. The S genome codes for a nucleocapsid (N) protein, which is quite conserved among different species of the ...
