Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

An Unstable Intermediate Carrying Information from Genes to Ribosomes for Protein Synthesis

Nature volume 190, pages 576–581 (1961)Cite this article

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Hall, B. D., and Doty, P., J. Mol. Biol., 1, 111 (1959). Littauer, U. Z., and Eisenberg, H., Biochim, Biophys. Acta, 32, 320 (1959). Kurland, C. G., J. Mol. Biol., 2, 83 (1960).

    Article  CAS  Google Scholar 

  2. Belozersky, A. N., Intern. Symp. Origin of Life. 194 (Publishing House of the Academy of Sciences of the U.S.S.R., 1957).

  3. Chargaff, E., The Nucleic Acids, 1, 307 (Academic Press, New York, 1955). Lee, K. Y., Wahl, R., and Barbu, E., Ann. Inst. Pasteur, 91, 212 (1956).

    Google Scholar 

  4. Riley, M., Pardee, A. B., Jacob, F., and Monod, J., J. Mol. Biol., 2, 216 (1960).

    Article  CAS  Google Scholar 

  5. Jacob, F., and Monod, J., J. Mol. Biol. (in the press).

  6. Cohen, S. S., J. Biol. Chem., 174, 218 (1948). Hershey, A. D., Dixon, J., and Chase, M., J. Gen. Physiol., 36, 777 (1953). Vidaver, G. A., and Kozloff, L. M., J. Biol. Chem., 225, 335 (1957).

    Google Scholar 

  7. Koch, G., and Hershey, A. D., J. Mol. Biol., 1, 260 (1959).

    Article  CAS  Google Scholar 

  8. Monod, J., and Wollman, E., Ann. Inst. Pasteur, 73, 937 (1947). Cohen, S. S., Bact. Rev., 13, 1 (1949). Pardee, A. B., and Williams, I., Ann. Inst. Pasteur, 84, 147 (1953).

    CAS  Google Scholar 

  9. Kornberg, A., Zimmerman, S. B., Kornberg, S. R., and Josse, J., Proc. U.S. Nat. Acad. Sci., 45, 772 (1959). Flaks, J. G., Lichten-stein, J., and Cohen, S. S., J. Biol. Chem., 234, 1507 (1959).

    Article  ADS  CAS  Google Scholar 

  10. Cohen, S. S., J. Biol. Chem., 174, 281 (1948). Manson, L. A., J. Bacteriol., 66, 703 (1953).

    CAS  PubMed  Google Scholar 

  11. Volkin, E., and Astrachan, L., Virology, 2, 149 (1956). Astrachan, L., and Volkin, E., Biochim. Biophys. Acta, 29, 544 (1958).

    Article  CAS  Google Scholar 

  12. Nomura, M., Hall, B. D., and Spiegelman, S., J. Mol. Biol., 2, 306 (1960).

    Article  CAS  Google Scholar 

  13. Meselson, M., Stahl, F. W., and Vinograd, J., Proc. U.S. Nat. Acad. Sci., 43, 581 (1957).

    Article  ADS  CAS  Google Scholar 

  14. Tissières, A., Watson, J. D., Schlessinger, D., and Hollingworth, B. R., J. Mol. Biol., 1, 221 (1959).

    Article  Google Scholar 

  15. McQuillen, K., Roberts, R. B., and Britten, R. J., Proc. U.S. Nat. Acad. Sci., 45, 1437 (1959).

    Article  ADS  CAS  Google Scholar 

  16. Gros, F., Hiatt, H., Gilbert, W., Kurland, C. G., Risebrough, R. W., and Watson, J. D., see following article.

  17. Brenner, S., and Eckhart, W. (unpublished results).

  18. Britten, R. J., and Roberts, R. B., Science, 131, 32 (1960).

    Article  ADS  CAS  Google Scholar 

  19. Tissières, A., Schlessinger, D., and Gros, F., Proc. U.S. Nat. Acad. Sci., 46, 1450 (1960).

    Article  ADS  Google Scholar 

  20. Volkin, E., Astrachan, L., and Countryman, J. L., Virology, 6, 545 (1958).

    Article  CAS  Google Scholar 

  21. Yeas, M., and Vincent, W. S., Proc. U.S. Nat. Acad. Sci., 46, 804 (1960).

    Article  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medical Research Council Unit for Molecular Biology, Cavendish Laboratory, University of Cambridge,

    S. BRENNER

  2. Institut Pasteur, Paris

    F. JACOB

  3. Gates and Crellin Laboratories of Chemistry, California Institute of Technology, Pasadena, California

    M. MESELSON

Authors
  1. S. BRENNER
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. JACOB
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. MESELSON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

BRENNER, S., JACOB, F. & MESELSON, M. An Unstable Intermediate Carrying Information from Genes to Ribosomes for Protein Synthesis. Nature 190, 576–581 (1961). https://doi.org/10.1038/190576a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/190576a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing