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Acknowledgements
We are indebted to C. Lindgren (core facility at the Kliniskt forskningscentrum, Karolinska Institute); J. Birmelin (University of Freiburg); S. Buckridge and A. Thrasher (Institute of Child Health) for the mutation analyses; R. Engqvist (Division of Clinical Immunology, Karolinska University Hospital Huddinge) for collection of family samples and A. Schaffer (National Center for Biotechnology Information, US National Institutes of Health) for statistical advice. This work was supported by ALF funding from the Stockholm County Council, the Swedish Research Council, the Deutsche Forschungsgemeinschaft (DFG) grant SFB620/C2, USIDnet grant NO1-A1-30070, the Primary Immunodeficiency Association, the Medical Research Council UK and European Union grant SP23-CT-2005-006411.
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Supplementary information
Supplementary Fig. 1
Mutations in TNFRSF13B in families with IgAD. (PDF 90 kb)
Supplementary Table 1
Mutations and sequence variants in TNFRSF13B in individuals with CVID and IgAD. (PDF 82 kb)
Supplementary Table 2
Primer sequences for detection of TNFRSF13B mutation and sequence variants using a SNP-based mutation assay. (PDF 67 kb)
Supplementary Table 3
Lack of correlation between heterozygous TNFRSF13B mutations and sequence variants and IgA deficiency. (PDF 67 kb)
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Pan-Hammarström, Q., Salzer, U., Du, L. et al. Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency. Nat Genet 39, 429â430 (2007). https://doi.org/10.1038/ng0407-429
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DOI: https://doi.org/10.1038/ng0407-429
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