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Privacy preserving error resilient dna searching through oblivious automata

Published: 28 October 2007 Publication History

Abstract

Human Desoxyribo-Nucleic Acid (DNA) sequences offer a wealth of information that reveal, among others, predisposition to various diseases and paternity relations. The breadth and personalized nature of this information highlights the need for privacy-preserving protocols. In this paper, we present a new error-resilient privacy-preserving string searching protocol that is suitable for running private DNA queries. This protocol checks if a short template (e.g., a string that describes a mutation leading to a disease), known to one party, is present inside a DNA sequence owned by another party, accounting for possible errors and without disclosing to each party the other party's input. Each query is formulated as a regular expression over a finite alphabet and implemented as an automaton. As the main technical contribution, we provide a protocol that allows to execute any finite state machine in an oblivious manner, requiring a communication complexity which is linear both in the number of states and the length of the input string.

References

[1]
Human gemome project. http://genomics.energy.gov
[2]
M. J. Atallah, F. Kerschbaum, and W. Du. Secure and private sequence comparisons. In Proceedings of the 2003 ACM Workshop on privacy in the electronic society, pages 39--44, Washington, DC, 2003. ACM Press.
[3]
M. J. Atallah and J. Li. Secure outsourcing of sequence comparisons. International Journal of Information Security, 4(4):23--36, October 2005.
[4]
R. E. Bellman. Dynamic Programming. Courier Dover Publications, 2003.
[5]
B. Chor, S. Goldwasser, S. Micali, and B. Awerbuch. Verifiable secret sharing and achieving simultaneity in the presence of faults. In 25th Annual Symposium on Foundations of Computer Science FOCS'85, pages 383--395. IEEE Computer Society, 1985.
[6]
I. Damgård, M. Fitzi, E. Kiltz, J. B. Nielsen, and T. Toft. Unconditionally secure constant-rounds multi-party computation for equality, comparison, bits and exponentiation. In Proceedings of the third Theory of Cryptography Conference, TCC 2006, volume 3876 of Lecture Notes in Computer Science, pages 285--304. Springer-Verlag, 2006.
[7]
O. Goldreich. Secure multi-party computation. Working Draft, 2002.
[8]
O. Goldreich, S. Micali, and A. Widgerson. How to play any mental game. In Proceedings of the nineteenth annual ACM conference on Theory of Computing, pages 218--229, New York, U.S.A., 1987. ACM Press.
[9]
S. Goldwasser and S. Micali. Probabilistic encryption. Journal of Computer and System Sciences, 28(2):270--299, April 1984.
[10]
A. Hall. Coming soon: Your personal dna map? http://news.nationalgeographic.com/news/2006/03/0307_060307_dna.html.
[11]
J. E. Hopcroft and J. D. Ullman. Introduction to automata theory, languages, and computation. Addison Wesley, 1979.
[12]
M. Jacobsson and A. Juels. Mix and match: Secure function evaluation via ciphertexts. In T. Okamoto, editor, Advances in Cryptology - ASIACRYPT'00, volume 1976 of Lecture Notes in Computer Science, pages 162--177. Springer-Verlag, 2000.
[13]
L. Kruger, S. Jha, E.-J. Goh, and D. Boneh. Secure function evaluation with ordered binary decision diagrams. In Proceedings of the 13th ACM conference on Computer and communications security CCS'06, pages 410--420, Virginia, U.S.A., November 2006. ACM Press.
[14]
V. I. Levenshtein. Binary codes capable of correcting deletions, insertions and reversals. Doklady Akademii Nauk SSSR, 163(4):845--848, 1965. English translation at Soviet Physics Doklady 10(8): 707--710, 1966.
[15]
M. Mohri. On some application of finite-state automata theory to natural language. Natural Language Engineering, 2(1):1--20, 1996.
[16]
M. Mohri. Finite-state transducers in language and speech processing. Computational Linguistics, 23(2):269--311, 1997.
[17]
M. Naor and K. Nissim. Communication complexity and secure function evaluation. Electronic Colloquium on Computational Complexity (ECCC), 8(062), 2001.
[18]
M. Naor and K. Nissim. Communication preserving protocols for secure function evaluation. In ACM Symposium on Theory of Computing, pages 590--599, 2001.
[19]
M. Naor and B. Pinkas. Efficient oblivious transfer protocols. In Proceedings of the twelfth annual ACM-SIAM symposium on Discrete algorithms, pages 448--457, Washington, D.C., U.S.A., 2001.
[20]
S. B. Needleman and C. D. Wunsch. A general method applicable to the search for similarities in the amino acid sequence of two proteins. Journal on Molecular Biology, 48:443--453, 1970.
[21]
P. Paillier. Public-key cryptosystems based on composite degree residuosity classes. In Advances in Cryptology - EUROCRYPT 1999, volume 1592 of Lecture Notes in Computer Science, pages 223--238. Springer, 1999.
[22]
K. U. Shulz and S. Mihov. Fast string correction with Levenshtein automata. International Journal of Document Analysis and Recognition (IJDAR), 5(1):67--85, 2002.
[23]
T. K. Vintsyuk. Speech discrimination by dynamic programming. Kibernetika, 4:52--57, 1968.
[24]
A. C. Yao. Protocols for secure computations. In Proceedings of the IEEE Symposium on Foundations of Computer Science, pages 160--164, 1982.
[25]
S. Yu and Q. Zhuang. The state complexities of some basic operations on regular languages. Theoretical Computer Science, 125:315--328, 1994.

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            cover image ACM Conferences
            CCS '07: Proceedings of the 14th ACM conference on Computer and communications security
            October 2007
            628 pages
            ISBN:9781595937032
            DOI:10.1145/1315245
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            Publication History

            Published: 28 October 2007

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            Author Tags

            1. approximate matching
            2. bioinformatics
            3. dna sarch
            4. finite automata
            5. homomorphic encryption
            6. levenshtein distance
            7. secure multiparty computation

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            CCS07: 14th ACM Conference on Computer and Communications Security 2007
            November 2 - October 31, 2007
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            CCS '07 Paper Acceptance Rate 55 of 302 submissions, 18%;
            Overall Acceptance Rate 1,261 of 6,999 submissions, 18%

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            • (2024)Optimized verifiable delegated private set intersection on outsourced private datasetsComputers & Security10.1016/j.cose.2024.103822(103822)Online publication date: Mar-2024
            • (2024)Unbalanced private set intersection with linear communication complexityScience China Information Sciences10.1007/s11432-022-3717-967:3Online publication date: 5-Feb-2024
            • (2024)Privacy-Preserving Regular Expression Matching Using TNFAComputer Security – ESORICS 202410.1007/978-3-031-70890-9_12(225-246)Online publication date: 6-Sep-2024
            • (2024)Garbled Circuit Lookup Tables with Logarithmic Number of CiphertextsAdvances in Cryptology – EUROCRYPT 202410.1007/978-3-031-58740-5_7(185-215)Online publication date: 26-May-2024
            • (2024)Private Set Operations from Multi-query Reverse Private Membership TestPublic-Key Cryptography – PKC 202410.1007/978-3-031-57725-3_13(387-416)Online publication date: 14-Apr-2024
            • (2024)Practical Single-Round Secure Wildcard Pattern MatchingICT Systems Security and Privacy Protection10.1007/978-3-031-56326-3_7(87-101)Online publication date: 24-Apr-2024
            • (2024)PrivMail: A Privacy-Preserving Framework for Secure EmailsComputer Security – ESORICS 202310.1007/978-3-031-51476-0_8(145-165)Online publication date: 11-Jan-2024
            • (2023)Balancing Security and Privacy in Genomic Range QueriesACM Transactions on Privacy and Security10.1145/357579626:3(1-28)Online publication date: 13-Mar-2023
            • (2023)A new ciphertext based OT protocol in cloud computing2023 4th International Seminar on Artificial Intelligence, Networking and Information Technology (AINIT)10.1109/AINIT59027.2023.10212517(408-413)Online publication date: 16-Jun-2023
            • (2022)Updatable Private Set IntersectionProceedings on Privacy Enhancing Technologies10.2478/popets-2022-00512022:2(378-406)Online publication date: 3-Mar-2022
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