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Leveraging the semantic web and natural language processing to enhance drug-mechanism knowledge in drug product labels

Published: 11 November 2010 Publication History

Abstract

Multiple studies indicate that drug-drug interactions are a significant source of preventable adverse drug events. Factors contributing to the occurrence of preventable ADEs resulting from DDIs include a lack of knowledge of the patient's concurrent medications and inaccurate or inadequate knowledge of interactions by health care providers. FDA-approved drug product labeling is a major source of information intended to help clinicians prescribe drugs in a safe and effective manner. Unfortunately, drug product labeling has been identified as often lagging behind emerging drug knowledge; especially when it has been several years since a drug has been released to the market. In this paper we report on a novel approach that explores employing Semantic Web technology and natural language processing to identify drug mechanism information that may update or expand upon statements present in product labeling.

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Cited By

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  • (2017)Toward a comprehensive drug ontology: extraction of drug-indication relations from diverse information sourcesJournal of Biomedical Semantics10.1186/s13326-016-0110-08:1Online publication date: 10-Jan-2017
  • (2016)Examining the effect of automated health explanations on older adults' attitudes toward medication informationProceedings of the 10th EAI International Conference on Pervasive Computing Technologies for Healthcare10.5555/3021319.3021346(186-193)Online publication date: 16-May-2016
  • (2013)Mining FDA drug labels for medical conditionsBMC Medical Informatics and Decision Making10.1186/1472-6947-13-5313:1Online publication date: 24-Apr-2013

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  1. Leveraging the semantic web and natural language processing to enhance drug-mechanism knowledge in drug product labels

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    cover image ACM Other conferences
    IHI '10: Proceedings of the 1st ACM International Health Informatics Symposium
    November 2010
    886 pages
    ISBN:9781450300308
    DOI:10.1145/1882992
    Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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    Published: 11 November 2010

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    Author Tags

    1. drug product labeling
    2. drug-drug interactions
    3. mash-up
    4. semantic web

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    IHI '10: ACM International Health Informatics Symposium
    November 11 - 12, 2010
    Virginia, Arlington, USA

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    View all
    • (2017)Toward a comprehensive drug ontology: extraction of drug-indication relations from diverse information sourcesJournal of Biomedical Semantics10.1186/s13326-016-0110-08:1Online publication date: 10-Jan-2017
    • (2016)Examining the effect of automated health explanations on older adults' attitudes toward medication informationProceedings of the 10th EAI International Conference on Pervasive Computing Technologies for Healthcare10.5555/3021319.3021346(186-193)Online publication date: 16-May-2016
    • (2013)Mining FDA drug labels for medical conditionsBMC Medical Informatics and Decision Making10.1186/1472-6947-13-5313:1Online publication date: 24-Apr-2013

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