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Evaluating the botanical coverage of PATO using an unsupervised learning algorithm

Published: 07 February 2012 Publication History
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  • Abstract

    In this paper, we explore issues in adopting PATO as a standard phenotypic quality ontology for the biological community. Using CharaParser's unsupervised learning algorithm and the Stanford Parser, we extract morphological descriptions from Flora of North America to be matched to terms in PATO. Using the resulting data, we examine PATO's coverage of botanically interesting terms in order to find gaps and to determine accuracy. To maintain PATO's neutrality, we recommend that term definitions be reevaluated and propose that complimentary ontologies be enhanced to close any outstanding gaps in terminology.

    References

    [1]
    Cui, H. (Submitted). CharaParser for Fine-Grained Semantic Annotation of Taxonomic Descriptions. Journal of American Society of Information Science and Technology.
    [2]
    Cui, H. (2010). Evaluating Plant Character Ontologies Against Domain Literature. Journal of American Society of Information Science and Technology. 61(6):1144--1165.
    [3]
    Klein, D. and Manning, C. D. 2003. Accurate Unlexicalized Parsing. In Proceedings of the 41st Meeting of the Association for Computational Linguistics, 423--430.
    [4]
    Knowlton, M. N., Li, T., Ren, Y. et. al. (2008). A PATO-compliant zebrafish screening database (MODB): management of morpholino knockdown screen information. BMC Bioinformatics, 9, 7 (January 2008). DOI= 10.1186/1471-2105-9-7.
    [5]
    PATO: http://www.bioontology.org/wiki/index.php/PATO:Main_Page
    [6]
    Smith B, Ashburner M, Rosse C, et. al. (2007). The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration. Nature Biotechnology, 25, 1251--1255.
    [7]
    Schindelman, G., Fernandes, J. S., Bastiani, C. A, Yook, K. and Sternberg, P. W. 2011. Worm Phenotype Ontology: Integrating phenotype data within and beyond the C. elegans community. BMC Bioinformatics, 12, 3.

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    Published In

    cover image ACM Other conferences
    iConference '12: Proceedings of the 2012 iConference
    February 2012
    667 pages
    ISBN:9781450307826
    DOI:10.1145/2132176

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    Association for Computing Machinery

    New York, NY, United States

    Publication History

    Published: 07 February 2012

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    Author Tags

    1. Flora of North America
    2. PATO
    3. Stanford Parser
    4. botany
    5. ontologies
    6. open biological ontologies
    7. unsupervised learning

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    iConference '12
    iConference '12: iConference 2012
    February 7 - 10, 2012
    Ontario, Toronto, Canada

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