research-article

The linked clinical data project: applying semantic web technologies for clinical and translational research using electronic medical records

Authors:

Jyotishman Pathak,

Richard C. Kiefer,

Christopher G. ChuteAuthors Info & Claims

SWAT4LS '11: Proceedings of the 4th International Workshop on Semantic Web Applications and Tools for the Life Sciences

Pages 94 - 95

https://doi.org/10.1145/2166896.2166920

Published: 07 December 2011 Publication History

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Abstract

Systematic study of clinical phenotypes is important to better understand the genetic basis of human diseases and more effective gene-based disease management. The Linked Clinical Data (LCD) project at Mayo Clinic aims to develop a semantics-driven framework for high-throughput phenotype extraction, representation, integration, and querying from electronic medical records using emerging Semantic Web technologies, such as Linked Open Data. This poster abstract provides a brief background and overview of the recently initiated LCD project.

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McCarty, C., et al., The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies. BMC Medical Genomics, 2011. 4(1): p. 13.

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Sherry, S. T., M. Ward, and K. Sirotkin, dbSNP,ÄîDatabase for Single Nucleotide Polymorphisms and Other Classes of Minor Genetic Variation. Genome Research, 1999. 9(8): p. 677--679.

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Hamosh, A., et al., Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Research, 2005. 33(suppl 1): p. D514--D517.

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Belleau, F., et al., Bio2RDF: Towards a mashup to build bioinformatics knowledge systems. Journal of Biomedical Informatics, 2008. 41(5): p. 706--716.

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Bielinski, S. J., et al., Mayo Genome Consortia: A Genotype-Phenotype Resource for Genome-Wide Association Studies With an Application to the Analysis of Circulating Bilirubin Levels. Mayo Clinic Proceedings, 2011. 86(7): p. 606--614.

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Cited By

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Meldolesi Evan Soest JDinapoli NDekker ADamiani AGambacorta MValentini V(2014)An umbrella protocol for standardized data collection (SDC) in rectal cancer: A prospective uniform naming and procedure convention to support personalized medicineRadiotherapy and Oncology10.1016/j.radonc.2014.04.008112:1(59-62)Online publication date: Jul-2014
https://doi.org/10.1016/j.radonc.2014.04.008

Index Terms

The linked clinical data project: applying semantic web technologies for clinical and translational research using electronic medical records
1. Computing methodologies
  1. Artificial intelligence
    1. Knowledge representation and reasoning
2. Information systems
  1. Data management systems
    1. Database management system engines
      1. Parallel and distributed DBMSs

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Published In

SWAT4LS '11: Proceedings of the 4th International Workshop on Semantic Web Applications and Tools for the Life Sciences

December 2011

139 pages

ISBN:9781450310765

DOI:10.1145/2166896

Conference Chairs:
Adrian Paschke
Freie Universitaet Berlin, Germany
,
Albert Burger
Heriot-Watt University, and Medical Research Council, Edinburgh, Scotland, United Kingdom
,
Paolo Romano
IST National Cancer Research Institute, Genova, Italy
,
M. Scott Marshall
University of Amsterdam, The Netherlands
,
Andrea Splendiani
Rothamsted Research, UK

Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for third-party components of this work must be honored. For all other uses, contact the Owner/Author.

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SIGBio: ACM Special Interest Group on Bioinformatics
IW3C2: International World Wide Web Conference Committee

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Association for Computing Machinery

New York, NY, United States

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Published: 07 December 2011

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Mayo Clinic

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SWAT4LS '11

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Corporate Semantic Web
BBRC
NCBO
BioMed Central

SWAT4LS '11: 4th Int. Workshop on Semantic Web Applications and Tools for Life Sciences

December 7 - 9, 2011

London, United Kingdom

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Meldolesi Evan Soest JDinapoli NDekker ADamiani AGambacorta MValentini V(2014)An umbrella protocol for standardized data collection (SDC) in rectal cancer: A prospective uniform naming and procedure convention to support personalized medicineRadiotherapy and Oncology10.1016/j.radonc.2014.04.008112:1(59-62)Online publication date: Jul-2014
https://doi.org/10.1016/j.radonc.2014.04.008

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Linked data publishing and ontology in Korea libraries

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Patient-Centered Clinical Trials Decision Support using Linked Open Data

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