Improving the human skin microanatomy understanding and skin aging observation with the SkinExplorer™ platform
Authors: 
Vazquez-Duchêne Marie-Danielle, Mion Christophe, Mine Solène, Jeanmaire Christine, Freis Olga, Pauly Gilles, Courtois Aurélie, Denis AlainAuthors Info & Claims
Vazquez-Duchêne Marie-Danielle, Mion Christophe, Mine Solène, Jeanmaire Christine, Freis Olga, Pauly Gilles, Courtois Aurélie, Denis AlainAuthors Info & ClaimsArticle No.: 9, Pages 1 - 4
Abstract
Background: The skin includes 3 major layers: epidermis, dermis and hypodermis. With aging, the human skin becomes thinner and flattens with dermal papillae being less pronounced. The epidermis becomes fine-drawn and the dermal network deteriorates with decades. The three-dimensional structure of elastic network and the hyaluronic acid distribution are so complex, rich and dense that the conventional observation ways can only provide partial view of these components.
Objective: The aim of this study was to demonstrate the morphological differences between two abdominal skin samples coming from young and aged donors based on elastic fibers organization and hyaluronic acid distribution.
Methods: The SkinExplorer™ platform performs immersive and interactive exploration with virtual reality applications.
Results: 2mm3 of histological data were obtained from 40 serial histological sections. Two three-dimensional numerical models from respectively young and aged skin biopsies were reconstructed. The observations were realized on the epidermis and dermal elastic fibers with the SkinExplorer™ platform and virtual reality (VR) applications. For hyaluronic acid repartition, two smaller models were reconstructed to see their richness and density by the same platform and VR tools.
Conclusion: These results suggest that Virtual Reality applications can be a good tool for the observation of aging process with its assessing and understanding. Moreover, this tool of exploration offers new way of micro-anatomical research.
References
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Pouradier, F., Cornillon, C., D'arras, M. F., Flament, F., Panhard, S., Diridollou, S. and Loussouarn, G. 2013. Functional and structural age-related changes in the scalp skin of Caucasian women. Skin Res Technol. 19, 384--393.
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Vazquez-Duchene, M. D., Kraemer, P., Saugnier, N., Levy, B., Mine, S., Jeanmaire, C., Freis O., Pauly, G., and Rathjens, A. 2013. SkinExplorer#8482;: a new high-tech platform to interact inside the skin by immersive virtual 3D cutaneous environment. Skin Res Technol. e1--e12.
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http://www.ar-tracking.com/home/
Index Terms
- Improving the human skin microanatomy understanding and skin aging observation with the SkinExplorer™ platform
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Published In
April 2014
193 pages
ISBN:9781450326261
DOI:10.1145/2617841
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Association for Computing Machinery
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Published: 09 April 2014
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VRIC '14
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- Laval Virtual
VRIC '14: Virtual Reality International Conference - Laval Virtual 2014
April 9 - 11, 2014
Laval, France
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