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Cyberinfrastructure of a Multi-Petabyte Microscopy Resource for Neuroscience Research

Published: 26 July 2020 Publication History

Abstract

Advances in microscopy technologies and techniques are driving development of an integrated cyberinfrastructure to manage the vast amounts of image data being generated. To address this need, a team of neuroscientists and cyberinfrastructure engineers has integrated mass storage, networking, and high-performance computing components to create the Brain Image Library (BIL). BIL serves the neuroscience community by providing a persistent repository for the massive amounts of data being generated (multi-petabyte scale) and by offering brain researchers supercomputing-class processing and visualization capabilities for working with high-resolution brain image datasets.

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  • (2024)Deciphering spatial domains from spatially resolved transcriptomics with Siamese graph autoencoderGigaScience10.1093/gigascience/giae00313Online publication date: 20-Feb-2024
  • (2024)Massive multiplexing of spatially resolved single neuron projections with axonal BARseqNature Communications10.1038/s41467-024-52756-x15:1Online publication date: 27-Sep-2024
  • (2023)Rebuilding BridgesPractice and Experience in Advanced Research Computing 2023: Computing for the Common Good10.1145/3569951.3597589(324-327)Online publication date: 23-Jul-2023
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cover image ACM Conferences
PEARC '20: Practice and Experience in Advanced Research Computing 2020: Catch the Wave
July 2020
556 pages
ISBN:9781450366892
DOI:10.1145/3311790
This work is licensed under a Creative Commons Attribution-ShareAlike International 4.0 License.

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Association for Computing Machinery

New York, NY, United States

Publication History

Published: 26 July 2020

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Author Tags

  1. image archive
  2. neuroscience
  3. storage architecture

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  • Research-article
  • Research
  • Refereed limited

Funding Sources

  • National Institute of Mental Health of the National Institutes of Health

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PEARC '20
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Overall Acceptance Rate 133 of 202 submissions, 66%

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Cited By

View all
  • (2024)Deciphering spatial domains from spatially resolved transcriptomics with Siamese graph autoencoderGigaScience10.1093/gigascience/giae00313Online publication date: 20-Feb-2024
  • (2024)Massive multiplexing of spatially resolved single neuron projections with axonal BARseqNature Communications10.1038/s41467-024-52756-x15:1Online publication date: 27-Sep-2024
  • (2023)Rebuilding BridgesPractice and Experience in Advanced Research Computing 2023: Computing for the Common Good10.1145/3569951.3597589(324-327)Online publication date: 23-Jul-2023
  • (2023)On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in EpilepsyPharmacoresistance in Epilepsy10.1007/978-3-031-36526-3_4(39-62)Online publication date: 30-Aug-2023
  • (2022)Microscopy-BIDS: An Extension to the Brain Imaging Data Structure for Microscopy DataFrontiers in Neuroscience10.3389/fnins.2022.87122816Online publication date: 19-Apr-2022
  • (2022)Seeing the Forest and Its Trees Together: Implementing 3D Light Microscopy Pipelines for Cell Type Mapping in the Mouse BrainFrontiers in Neuroanatomy10.3389/fnana.2021.78760115Online publication date: 14-Jan-2022
  • (2022)Standard metadata for 3D microscopyScientific Data10.1038/s41597-022-01562-59:1Online publication date: 27-Jul-2022

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