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Spindle Density Analysis of Adult Epilepsy based on Automatic Detection Algorithms in EEG

Published: 09 December 2022 Publication History

Abstract

Electrophysiological investigations of sleep provide an important advantage for recording spontaneous neural activity and quantifying brain function. This study combined artificial intelligence technology to quantitatively analyze spindle density in adult patients with epilepsy. All patients received one-night sleep electroencephalogram monitoring. We employed a convolutional neural network-based sleep staging system to predict sleep macrostructure. Then we applied two species of advanced algorithms: Spindler and Latent state spindle detector, to automatically detect sleep spindle during non-rapid eye movement sleep stage 2. And we calculated three kinds of frequency range spindle density involving 11-17 Hz, 9-12 Hz, and 12-15 Hz. Our results suggested that 11-17 Hz and 12-15 Hz spindle density in adult epilepsy predominated in parietal and 9-12 Hz spindle density in prefrontal regions.

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          cover image ACM Other conferences
          ISAIMS '22: Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences
          October 2022
          594 pages
          ISBN:9781450398442
          DOI:10.1145/3570773
          Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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          Published: 09 December 2022

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          Author Tags

          1. Adult epilepsy
          2. Automatic detection
          3. Sleep EEG
          4. Spindle density

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