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Numerical integration of a differential-difference equation with a decreasing time-lag

Published: 01 April 1965 Publication History

Abstract

Systems in which variable time-lags are present are of common occurrence in biology. Variable flow rates are a common cause of these variable lags. At present no extensive body of knowledge exists concerning the effects which these variable lags can cause. Shown here is a method of reducing some differential-difference equations to ordinary differential equations which can then be studied numerically with ease. Subsequent study will deal with situations in which multiple-lags and lags dependent on the solution itself are present.

References

[1]
BELLMAN, R. E., JACQUEZ, J., AND KALABA, R. E. Mathematical models of chemotherapy. Proceedings of the Fourth Berkeley Symposium on Mathematical Statistics and Probability, Vol. IV, Biology and Problems of Health. U. of California Press, Berkeley, 1961, 57-66.
[2]
--. From chemotherapy to computers to trajectories. In Mathematical Problems in the Biological Sciences. R. E. Bellman (Ed.), Amer. Math. Soc., Providence, R. I., 1962, 225- 231.
[3]
--, KALABA, R. E., AND KOTKIN, B. Differential approximation applied to the solution of convolution equations. Math. Comput. 18, 87 (July 1964), 487-491.

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  1. Numerical integration of a differential-difference equation with a decreasing time-lag

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      cover image Communications of the ACM
      Communications of the ACM  Volume 8, Issue 4
      April 1965
      63 pages
      ISSN:0001-0782
      EISSN:1557-7317
      DOI:10.1145/363831
      Issue’s Table of Contents
      Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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      Association for Computing Machinery

      New York, NY, United States

      Publication History

      Published: 01 April 1965
      Published in CACM Volume 8, Issue 4

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