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Computational analysis of the oscillatory behavior at the translation level induced by mRNA levels oscillations due to finite intracellular resources

Fig 6

The RFM as a chain of n sites of codons.

Each site is described by a state variable xi(t) ∈ [0, 1], expressing the normalized ribosome occupancy at site i at time t. λ0 is the initiation rate, and λi is the elongation rate from site i to site i + 1. Translation rate at time t is R(t) ≔ λnxn(t).

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1006055.g006