Production of [124I]-iodine on an 11 MeV cyclotron

Jonathon A. Nye; Miguel A. Avila-Rodriguez; Robert J. Nickles

doi:10.1524/ract.2006.94.4.213

Published by De Gruyter (O) September 25, 2009

Production of [¹²⁴I]-iodine on an 11 MeV cyclotron

Jonathon A. Nye , Miguel A. Avila-Rodriguez and Robert J. Nickles

From the journal Radiochimica Acta

https://doi.org/10.1524/ract.2006.94.4.213

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Summary

The radiohalogen, ¹²⁴I, was produced by the ¹²⁴Te(p,n) reaction from a glassy ¹²⁴TeO₂/6%Al₂O₃ melt on an 11 MeV proton cyclotron. A 20-degree inclined target withstands beam currents up to 20 μA with no physical damage to the substrate surface. Radioiodine was removed from the glassy melt by dry distillation techniques and trapped on cooled platinum wire. The radiochemical purity, determined by ion chromatography, shows a stable product in the iodide form over a lifetime of weeks.

Keywords: [124I]-iodine; Biomedical cyclotron; Radiohalogens; Tellurium dioxide; CTI RDS 112; Positron emission tomography

Published Online: 2009-9-25

Published in Print: 2006-4-1

Production of [¹²⁴I]-iodine on an 11 MeV cyclotron

Summary

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