Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Nexus Implicated in Bowel Disease Pathophysiology
Abstract
:1. Introduction
2. Endoplasmic Reticulum
3. Endoplasmic Reticulum Stress
4. Unfolded Protein Response (UPR)
4.1. Inositol-Requiring Protein 1 (IRE1)
4.2. Protein Kinase-Like Endoplasmic Reticulum Kinase (PERK)
4.3. Activating Transcription Factor 6 (ATF6)
5. Protein Folding Challenge in Intestinal Secretory Cells
6. Endoplasmic Reticulum Stress and Autophagy
7. Oxidative Stress
8. Vicious Sequence of Events between Endoplasmic Reticulum Stress and Oxidative Stress
9. Endoplasmic Reticulum Stress and Oxidative Stress in Inflammatory Bowel Disease
10. Conclusions and Future Directions
Conflicts of Interest
References
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Chong, W.C.; Shastri, M.D.; Eri, R. Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Nexus Implicated in Bowel Disease Pathophysiology. Int. J. Mol. Sci. 2017, 18, 771. https://doi.org/10.3390/ijms18040771
Chong WC, Shastri MD, Eri R. Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Nexus Implicated in Bowel Disease Pathophysiology. International Journal of Molecular Sciences. 2017; 18(4):771. https://doi.org/10.3390/ijms18040771
Chicago/Turabian StyleChong, Wai Chin, Madhur D. Shastri, and Rajaraman Eri. 2017. "Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Nexus Implicated in Bowel Disease Pathophysiology" International Journal of Molecular Sciences 18, no. 4: 771. https://doi.org/10.3390/ijms18040771