Issue 7, 2009
From the journal:

Organic & Biomolecular Chemistry

Trifunctional organocatalyst-promoted counterion catalysis for fast and enantioselective aza-Morita–Baylis–Hillman reactions at ambient temperature†

Jean-Marc Garniera  and  Fei Liu*a  

* Corresponding authors

a Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW, Australia
E-mail: fliu@alchemist.chem.mq.edu.au
Fax: +61-2-9850-8313
Tel: +61-2-9850-8312

Abstract

Fast and enantioselective aza-Morita–Baylis–Hillman reactions between electron-deficient or electron-rich aromatic N-tosyl imines and methyl vinyl ketone were achieved at ambient temperature using asymmetric counterion-directed catalysis promoted by trifunctional organocatalysts with a Brønsted base as the activity switch after protonation with benzoic acid.

Graphical abstract: Trifunctional organocatalyst-promoted counterion catalysis for fast and enantioselective aza-Morita–Baylis–Hillman reactions at ambient temperature

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B901781J
Article type
Communication
Submitted
27 Jan 2009
Accepted
03 Feb 2009
First published
18 Feb 2009

Org. Biomol. Chem., 2009,7, 1272-1275

Permissions

Request permissions

Trifunctional organocatalyst-promoted counterion catalysis for fast and enantioselective aza-Morita–Baylis–Hillman reactions at ambient temperature

J. Garnier and F. Liu, Org. Biomol. Chem., 2009, 7, 1272 DOI: 10.1039/B901781J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements