AKIRIN2

Akirin-2 is a protein that in humans is encoded by the AKIRIN2 gene.

AKIRIN2
Identifiers
Aliases	AKIRIN2, C6orf166, FBI1, dJ486L4.2, akirin 2
External IDs	OMIM: 615165; MGI: 1889364; HomoloGene: 9988; GeneCards: AKIRIN2; OMA:AKIRIN2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6q15 Start 87,674,860 bp End 87,702,233 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 A5 Start 34,550,937 bp End 34,566,908 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte monocyte secondary oocyte ganglionic eminence ventricular zone myocardium of left ventricle gastrocnemius muscle cardiac muscle tissue of right atrium muscle of thigh granulocyte Top expressed in zygote oocyte primary oocyte secondary oocyte Ileal epithelium medial ganglionic eminence vestibular sensory epithelium seminiferous tubule abdominal wall primitive streak More reference expression data BioGPS More reference expression data
Gene ontology Molecular function enzyme binding protein binding Cellular component transcription repressor complex nucleus nucleoplasm Biological process multicellular organism development positive regulation of endopeptidase activity response to lipopolysaccharide innate immune response negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II negative regulation of gene expression transcription, DNA-templated positive regulation of cell population proliferation positive regulation of interleukin-6 production positive regulation of transcription by RNA polymerase II immune system process embryo development ending in birth or egg hatching Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55122 433693 Ensembl ENSG00000135334 ENSMUSG00000028291 UniProt Q53H80 B1AXD8 RefSeq (mRNA) NM_018064 NM_001007589 NM_026019 RefSeq (protein) NP_060534 NP_001007590 Location (UCSC) Chr 6: 87.67 – 87.7 Mb Chr 4: 34.55 – 34.57 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

External links

• Human AKIRIN2 genome location and AKIRIN2 gene details page in the UCSC Genome Browser.

Further reading

• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.