Palazzo dello Sport may refer to:
- Milan
- Palazzo dello Sport (Milan), the original sports palace of Milan, built in 1923
- Palasport di San Siro, also called Palazzone or Palazzetto dello Sport di Milano, open from 1976 to 1985
- PalaSharp or Palazzetto dello Sport, open from 1986 to 2011
- Rome
- PalaLottomatica or Palazzo dello Sport
- Palazzetto dello Sport