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Nitrox

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Typical Nitrox cylinder marking

Nitrox refers to any gas mixture composed (excluding trace gases) of nitrogen and oxygen; this includes normal air which is approximately 78% nitrogen, 21% oxygen, and 1% other gases, primarily argon.[1][2][3] However, in scuba diving, nitrox is normally differentiated and handled differently from air.[3] The most common use of nitrox mixtures containing higher than normal levels of oxygen is in scuba, where the reduced percentage of nitrogen is advantageous in reducing nitrogen uptake in the body's tissues and so extending the possible dive time, and/or reducing the risk of decompression sickness (also known as the bends).

Purpose

Enriched Air Nitrox diving tables, showing adjusted no-decompression times.

Enriched Air Nitrox, nitrox with an oxygen content above 21%, is mainly used in scuba diving to reduce the proportion of nitrogen in the breathing gas mixture. Reducing the proportion of nitrogen by increasing the proportion of oxygen reduces the risk of decompression sickness for the same dive profile, or allows extended dive times without increasing the need for decompression stops for the same risk. Nitrox is not a safer gas than compressed air in all respects; although its use can reduce the risk of decompression sickness, it increases the risk of oxygen toxicity and fire, which are further discussed below.

Breathing nitrox is not thought to reduce the effects of narcosis, as oxygen seems to have equally narcotic properties under pressure as nitrogen; thus one should not expect a reduction in narcotic effects due only to the use of nitrox.[4][5][note 1] Nonetheless, there are people in the diving community who insist that they feel reduced narcotic effects at depths breathing nitrox.[note 2] This may be due to a dissociation of the subjective and behavioural effects of narcosis.[6] However, it should be noted that because of risks associated with oxygen toxicity, divers tend not to utilize nitrox at greater depths where more pronounced narcosis symptoms are more likely to occur. For a reduction in narcotic effects trimix or heliox, gases which also contain helium, are generally used by divers.

There is anecdotal evidence that the use of nitrox reduces post-dive fatigue,[7] particularly in older and or obese divers; however a double-blind study to test this found no statistically significant reduction in reported fatigue.[1][8] There was, however, some suggestion that post dive fatigue is due to sub-clinical decompression sickness (DCS) (i.e. micro bubbles in the blood insufficient to cause symptoms of DCS); the fact that the study mentioned was conducted in a dry chamber with an ideal decompression profile may have been sufficient to reduce sub-clinical DCS and prevent fatigue in both nitrox and air divers. In 2008, a study was published using wet divers at the same depth and confirmed that no statistically significant reduction in reported fatigue is seen.[9]

Further studies with a number of different dive profiles, and also different levels of exertion, would be necessary to fully investigate this issue. For example, there is much better scientific evidence that breathing high-oxygen gases increase exercise tolerance, during aerobic exertion.[10] Though even moderate exertion while breathing from the regulator is a relatively uncommon occurrence in scuba, as divers usually try to minimize it in order to conserve gas, episodes of exertion while regulator-breathing do occasionally occur in sport diving. Examples are surface-swimming a distance to a boat or beach after surfacing, where residual "safety" cylinder gas is often used freely, since the remainder will be wasted anyway when the dive is completed. It is possible that these so-far un-studied situations have contributed to some of the positive reputation of nitrox.

Naming

Nitrox is known by many names: Enhanced Air Nitrox, Oxygen Enriched Air, Nitrox, EANx or Safe Air.[3][11] The name "nitrox" may be capitalized when referring to specific mixtures such as Nitrox32, which contains 68% nitrogen and 32% oxygen. When one figure is stated, it refers to the oxygen percentage, not the nitrogen percentage. The original convention, Nitrox68/32 became shortened as the first figure is redundant.[citation needed]

Although "nitrox" usually refers to a mixture of nitrogen and oxygen with more than 21% oxygen, it can refer to mixtures that are leaner in oxygen than air.[3] "Enriched Air Nitrox", "Enriched Air" or "EAN" are used to emphasise richer than air mixtures.[3] In "EANx", the "x" indicates the percentage of oxygen in the mix and is replaced by a number when the percentage is known; for example a 40% oxygen mix is called EAN40. The two most popular blends are EAN32 and EAN36 (also named Nitrox I and Nitrox II, respectively, or Nitrox68/32 and Nitrox64/36).[2][3]

In its early days of introduction to non-technical divers, nitrox has occasionally also been known by detractors by less complimentary terms, such as "devil gas" or "voodoo gas" (a term now sometimes used with pride).[citation needed]

These percentages are what the gas blender aims for in partial-pressure blending, but the final actual mix in such cases will be unique, and so a small flow of gas from the cylinder must be measured with a handheld oxygen analyzer, before the diver breathes from the cylinder underwater.[12]

Richness of mix

Technical divers preparing for a mixed-gas decompression dive in Bohol, Philippines. Note the backplate and wing setup with sidemounted stage tanks containing EAN50 (left side) and pure oxygen (right side).

The two most common recreational diving nitrox mixes contain 32% and 36% oxygen, which have maximum operating depths (MODs) of 34 metres (112 ft) and 29 metres (95 ft) respectively when limited to a maximum partial pressure of oxygen of 1.4 bar (140 kPa). Divers may calculate an equivalent air depth to determine their decompression requirements or may use nitrox tables or a nitrox-capable dive computer.[2][3][13][14]

Nitrox with more than 40% oxygen is uncommon within recreational diving. There are two main reasons for this: the first is that all pieces of diving equipment that come into contact with mixes containing higher proportions of oxygen, particularly at high pressure, need special cleaning and servicing to reduce the risk of fire.[2][3] The second reason is that richer mixes extend the time the diver can stay underwater without needing decompression stops far further than the duration of typical diving cylinders. For example, based on the PADI nitrox recommendations, the maximum operating depth for EAN45 would be 21 metres (69 ft) and the maximum dive time available at this depth even with EAN36 is nearly 1 hour 15 minutes: a diver with a breathing rate of 20 litres per minute using twin 10 litre, 230 bar (about double 85 cu. ft.) cylinders would have completely emptied the cylinders after 1 hour 14 minutes at this depth.

Usage of nitrox mixtures containing 50% to 80% oxygen is common in technical diving as a decompression gas, which by virtue of its lower partial pressure of inert gases such as nitrogen and helium, allows for more efficient (faster) elimination of these gases from the tissues than leaner oxygen mixtures.

In deep open circuit technical diving, where hypoxic gases are breathed during the bottom portion of the dive, a Nitrox mix with 50% or less oxygen called a "travel mix" is sometimes breathed during the beginning of the descent in order to avoid hypoxia. Normally, however, the most oxygen-lean of the diver's decompression gases would be used for this purpose, since descent time spent reaching a depth where bottom mix is no longer hypoxic is normally small, and the distance between this depth and the MOD of any nitrox decompression gas is likely to be very short, if it occurs at all.

Cylinder markings to identify contents

Any cylinder containing any blend of gas other than the standard air content is required by most diving training organizations and some national governments,[15] to be clearly marked. Some organizations, e.g. GUE, argue that it does not make sense to have a permanent marking on a gas tank that can be filled with any gas.

Regional standards and conventions

Unspecified region, possibly USA

The standard[citation needed] nitrox cylinder is yellow in color and marked with a green band around the shoulder of the tank, with Nitrox or "Enriched air" marked in white or yellow letters inside. Tanks of any other color are generally marked with six inch band around the shoulder, with a one inch yellow band on the top and bottom, with four inches of green in the middle. This green band will also have the designation of "NITROX" or something similar inside, in yellow or white letters.

South Africa

South African National Standard 10019:2008 specifies the colour of all scuba cylinders as Golden yellow with French gray shoulder. This applies to all underwater breathing gases except medical oxygen, which must be carried in cylinders which are Black with a White shoulder. Nitrox cylinders must be identified by a transparent self-adhesive label with green lettering, fitted below the shoulder.[15] In effect this is green lettering on a yellow cylinder, with a gray shoulder. The composition of the gas must also be specified on the label. In practice this is done by a small additional self adhesive label with the oxygen fraction, which is changed when a new mix is filled.

Other markings

Cylinder showing Nitrox band and sticker marked with MOD and O2%

Every nitrox cylinder should also have a sticker stating whether or not the cylinder is oxygen clean and suitable for partial pressure blending. Any oxygen clean cylinder may have any mix up to 100% oxygen inside. If by some accident an oxygen clean cylinder is filled at a station which does not supply gas to oxygen-clean standards it is then considered contaminated and must be re-cleaned before a gas containing more than 40% oxygen may again be added.[16] Cylinders marked as not-oxygen clean may only be filled with enriched oxygen mixtures from membrane or stick blending systems where the gas is mixed before being added to the cylinder, and to oxygen fraction not exceeding 40%.

Finally, all nitrox cylinders should have a tag that, at minimum, states the oxygen content of the cylinder, the date it was blended, the gas blender's name, and the maximum operating depth along with the partial pressure this depth was calculated with[citation needed] . Other requirements may be made as to what is marked on the cylinder, but these markings are considered standard and safe by the diving community[citation needed], and any cylinders lacking these markings may be considered possibly unsafe. Training for nitrox certification suggests this tag be verified by the diver by using an oxygen analyzer before use.

Dangers

Oxygen toxicity

Diving and handling nitrox raises a number of potentially fatal dangers due to the high partial pressure of oxygen (ppO2).[2][3] Nitrox is not a deep-diving gas mixture owing to the increased proportion of oxygen, which becomes toxic when breathed at high pressure. For example, the maximum operating depth of nitrox with 36% oxygen, a popular recreational diving mix, is 29 metres (95 ft) to ensure a maximum ppO2 of no more than 1.4 bar (140 kPa). The exact value of the maximum allowed ppO2 and maximum operating depth varies depending on factors such as the training agency, the type of dive, the breathing equipment and the level of surface support, with professional divers sometimes being allowed to breathe higher ppO2 than those recommended to recreational divers.

To dive safely with nitrox, the diver must learn good buoyancy control, a vital part of scuba diving in its own right, and a disciplined approach to preparing, planning and executing a dive to ensure that the ppO2 is known, and the maximum operating depth is not exceeded. Most dive shops, dive operators, and gas blenders require the diver to have a nitrox certification card before selling nitrox to divers.

Some training agencies, such as Technical Diving International, teach the use of two depth limits to protect against oxygen toxicity. The shallower depth is called the "maximum operating depth" and is reached when the partial pressure of oxygen in the breathing gas reaches 1.4 bar (140 kPa). The deeper depth, called the "contingency depth", is reached when the partial pressure reaches 1.6 bar (160 kPa).[citation needed] Diving at or beyond this level exposes the diver to the risk of central nervous system (CNS) oxygen toxicity. This can be extremely dangerous since its onset is often without warning and can lead to drowning, as the regulator may be spat out during convulsions, which occur in conjunction with sudden unconsciousness (general seizure induced by oxygen toxicity).

Divers trained to use nitrox memorise the acronym VENTID-C (which stands for Vision (blurriness), Ears (ringing sound), Nausea, Twitching, Irritability, Dizziness, and Convulsions). However, evidence from non-fatal oxygen convulsions indicates that most convulsions are not preceded by any warning symptoms at all.[17] Further, many of the suggested warning signs are also symptoms of nitrogen narcosis, and so may lead to misdiagnosis by a diver. A solution to either is to ascend to a shallower depth.

Precautionary procedures at the fill station

Many training agencies such as PADI,[18] CMAS, SSI and NAUI train their divers to personally check the oxygen percentage content of each nitrox cylinder before every dive. If the oxygen percentage deviates by more than 1% from the value written on the cylinder by the gas blender, the scuba diver must either recalculate his or her bottom times with the new mix, or else abort the dive to remain safe and avoid oxygen toxicity or decompression sickness. Under IANTD and ANDI rules for use of nitrox,[19] which are followed by most dive resorts around the world, filled nitrox cylinders are signed out personally in a gas blender log book, which contains, for each cylinder and fill, the cylinder number, the measured oxygen percent composition, the signature of the receiving diver (who should have personally measured the oxygen percent with an instrument at the fill-shop), and finally a calculation of the maximum operating depth for that fill/cylinder. All of these steps minimize danger but increase complexity of operations (for example, personalized cylinders for each diver must generally be kept track of on dive boats with nitrox, which is not the case with generic compressed air cylinders).

Fire and toxic cylinder contamination from oxygen reactions

Diving cylinders are usually filled with nitrox by a gas blending technique such as partial pressure blending or premix decanting (in which a nitrox mix is supplied to the filler in pressurized larger cylinders). A few facilities have begun to fill cylinders with air which has been enriched with oxygen by a pre-mixing process, so that it is pressurized as nitrox for the first time in the diving cylinder. The pre-mixing is accomplished either by a membrane system which removes nitrogen from the air during compression or by a 'stick' blending technique where pure oxygen is mixed with air in a baffled chamber attached to the compressor intake.

With the use of pure oxygen during "partial pressure blending" (where pure oxygen is added from a large oxygen cylinder to the nearly empty dive cylinder until it reaches 300–500 psi (20–30 bar) before air is added by compressor) there is an especially increased risk of fire. Partial pressure blending using pure oxygen is often used to provide nitrox for multiple dives on live-aboard dive boats, but it is also used in some dive shops and clubs.

However, any gas which contains a significantly larger percentage of oxygen than air is a fire hazard. Furthermore, such gases can also react with hydrocarbons or incorrect lubricants inside a dive cylinder to produce carbon monoxide, even if a recognized fire does not happen. At present, there is some discussion over whether or not mixtures of gas which contain less than 40% oxygen may sometimes be exempt from oxygen clean standards.[20] Some of the controversy comes from a single U.S. regulation intended for commercial divers (not recreational divers) years ago.[3] However, the U.S. Compressed Gas Association (CGA) and two international nitrox teaching agencies (IANTD and ANDI)[citation needed] now support the standard that any gas containing more than 23.5% oxygen should be treated as nitrox (which is to say, no differently from pure oxygen) for purposes of oxygen cleanliness and oxygen compatibility (i.e., oxygen "servicability"). However, the largest training agency - PADI - is still teaching that pre-mixed nitrox (i.e. nitrox which is mixed before being put into the cylinder) below 40% oxygen does not require a specially cleaned cylinder or other equipment.[2][3][18] Most nitrox fill stations which supply pre-mixed nitrox will fill non-oxygen clean cylinders with mixtures below 40%. For a history of this controversy[3] see Luxfer cylinders.

History

In the 1920s or 1930s Draeger of Germany made a nitrox backpack independent air supply for a standard diving suit.

In World War II or soon after, British commando frogmen and work divers started sometimes diving with oxygen rebreathers adapted for semi-closed-circuit nitrox (which they called "mixture") diving by fitting larger cylinders and carefully setting the gas flow rate using a flow meter. These developments were kept secret until independently duplicated by civilians in the 1960s.

In the 1950s the United States Navy (USN) documented enriched oxygen gas procedures for military use of what we today call nitrox, in the USN Diving Manual.[21]

In 1970, Dr. Morgan Wells, who was the first director of the National Oceanographic and Atmospheric Administration (NOAA) Diving Center, began instituting diving procedures for oxygen-enriched air. He also developed a process for mixing oxygen and air which he called a continuous blending system. For many years Dr. Wells' invention was the only practical alternative to partial pressure blending. In 1979 NOAA published Wells' procedures for the scientific use of nitrox in the NOAA Diving Manual.[2][3]

In 1985 Dick Rutkowski, a former NOAA diving safety officer, formed IAND (International Association of Nitrox Divers) and began teaching nitrox use for recreational diving. This was considered dangerous by some, and met with heavy skepticism by the diving community.

In 1991, in a watershed moment, the annual DEMA show (held in Houston, Texas that year) banned nitrox training providers from the show. This created a backlash, and when DEMA relented, a number of organisations took the opportunity to present nitrox workshops outside the show. In 1992 BSAC banned its members from using nitrox.

In 1992 IAND's name was changed to the International Association of Nitrox and Technical Divers (IANTD), the T being added when the European Association of Technical Divers (EATD) merged with IAND. In the early 1990s, these agencies were teaching nitrox, but the main scuba agencies were not. Additional new organizations, including the American Nitrox Divers International (ANDI) - which invented the term "Safe Air" for marketing purposes - and Technical Diving International (TDI) were begun.

Meanwhile, diving stores were finding a purely economic reason to offer nitrox: not only was an entire new course and certification needed to use it, but instead of cheap or free tank fills with compressed air, dive shops found they could charge premium amounts of money for custom-gas blending of nitrox to their ordinary moderately experienced divers. With the new dive computers which could be programmed to allow for the longer bottom-times and shorter residual nitrogen times which nitrox gave, the incentive for the sport diver to use the gas increased. An intersection of economics and scientific validity had occurred.

In 1993 Skin Diver magazine, the leading recreational diving publication at the time, published a three part series arguing that nitrox was unsafe for sport divers.[22] Against this trend, in 1992 NAUI became the first existing major sport diver training agency to sanction nitrox.

In 1993 Dive Rite manufactured the first nitrox compatible dive computer, called the Bridge.[23]

In 1994 BSAC reversed it's policy on Nitrox and announced BSAC nitrox training to start in 1995[24]

In 1996, the Professional Association of Diving Instructors (PADI) announced full educational support for nitrox.[18] While other main line scuba organizations had announced their support of nitrox earlier,[24] it was PADI's endorsement that put nitrox over the top as a standard sport diving "option."[25]

Nitrox in nature

Sometimes in the geologic past the Earth's atmosphere contained much more than 20% oxygen: e.g. up to 35% in the Upper Carboniferous. This let animals absorb oxygen more easily and influenced evolution.[26][27]

See also

References

  1. ^ a b Brubakk, A. O. (2003). Bennett and Elliott's physiology and medicine of diving, 5th Rev ed. United States: Saunders Ltd. p. 800. ISBN 0702025712. {{cite book}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  2. ^ a b c d e f g Joiner, J. T. (2001). NOAA Diving Manual: Diving for Science and Technology, Fourth Edition. United States: Best Publishing. p. 660. ISBN 0941332705.
  3. ^ a b c d e f g h i j k l m Lang, M.A. (2001). DAN Nitrox Workshop Proceedings. Durham, NC: Divers Alert Network. p. 197. Retrieved 2008-05-02.
  4. ^ Hesser, CM (1978). "Roles of nitrogen, oxygen, and carbon dioxide in compressed-air narcosis". Undersea Biomedical Research. 5 (4). Bethesda, Md: Undersea and Hyperbaric Medical Society: 391–400. ISSN 0093-5387. OCLC 2068005. PMID 734806. Retrieved 2008-04-08. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
  5. ^ Brubakk, Alf O (2003). Bennett and Elliott's physiology and medicine of diving, 5th Rev ed. United States: Saunders Ltd. p. 304. ISBN 0702025712. {{cite book}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  6. ^ Hamilton K, Laliberté MF, Fowler B (1995). "Dissociation of the behavioral and subjective components of nitrogen narcosis and diver adaptation". Undersea and Hyperbaric Medicine. 22 (1). Undersea and Hyperbaric Medical Society: 41–9. PMID 7742709. Retrieved 2009-01-27. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  7. ^ "How does nitrox make you feel?". ScubaBoard. 2007. Retrieved 2009-05-21.
  8. ^ Harris RJ, Doolette DJ, Wilkinson DC, Williams DJ (2003). "Measurement of fatigue following 18 msw dry chamber dives breathing air or enriched air nitrox". Undersea and Hyperbaric Medicine. 30 (4). Undersea and Hyperbaric Medical Society: 285–91. PMID 14756231. Retrieved 2008-05-02.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  9. ^ Chapman SD, Plato PA. Measurement of Fatigue following 18 msw Open Water Dives Breathing Air or EAN36. In: Brueggeman P, Pollock NW, eds. Diving for Science 2008. Proceedings of the American Academy of Underwater Sciences 27th Symposium. http://archive.rubicon-foundation.org/8005. Retrieved 2009-05-21. {{cite journal}}: Missing or empty |title= (help)CS1 maint: numeric names: authors list (link)
  10. ^ Ergogenic Aids
  11. ^ Elliott, D (1996). "Nitrox". South Pacific Underwater Medicine Society Journal. 26 (3). ISSN 0813-1988. OCLC 16986801. Retrieved 2008-05-02.
  12. ^ Lippmann, John; Mitchell, Simon J (2005). "28". Deeper into Diving (2 ed.). Victoria, Australia: J.L. Publications. pp. 403–4. ISBN 097522901X. OCLC 66524750. {{cite book}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  13. ^ Logan, JA (1961). "An evaluation of the equivalent air depth theory". United States Navy Experimental Diving Unit Technical Report. NEDU-RR-01-61. Retrieved 2008-05-01.
  14. ^ Berghage Thomas E, McCraken TM (1979). "Equivalent air depth: fact or fiction". Undersea Biomedical Research. 6 (4): 379–84. PMID 538866. Retrieved 2008-05-01. {{cite journal}}: Unknown parameter |month= ignored (help)
  15. ^ a b South African National Standard 10019:2008, Transportable containers for compressed, dissolved and liquefied gases - Basic design, manufacture, use and maintenance, Standards South Africa, Pretoria
  16. ^ Butler, Glen L; Mastro, Steven J; Hulbert, Alan W; Hamilton Jr, Robert W. (1992). "Oxygen safety in the production of enriched air nitrox breathing mixtures". In: Cahoon, LB. (ed.) Proceedings of the American Academy of Underwater Sciences Twelfth Annual Scientific Diving Symposium "Diving for Science 1992". Held September 24–27, 1992 at the University of North Carolina at Wilmington, Wilmington, NC. American Academy of Underwater Sciences. Retrieved 2011-01-11.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  17. ^ Clark, James M; Thom, Stephen R (2003). "Oxygen under pressure". In Brubakk, Alf O; Neuman, Tom S (eds.). Bennett and Elliott's physiology and medicine of diving (5th ed.). United States: Saunders. p. 375. ISBN 0702025712. OCLC 51607923.
  18. ^ a b c Richardson, D and Shreeves, K (1996). "The PADI Enriched Air Diver course and DSAT oxygen exposure limits". South Pacific Underwater Medicine Society Journal. 26 (3). ISSN 0813-1988. OCLC 16986801. Retrieved 2008-05-02.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  19. ^ http://www.andihq.com/pages/mainpage.html
  20. ^ Rosales KR, Shoffstall MS, Stoltzfus JM (2007). "Guide for Oxygen Compatibility Assessments on Oxygen Components and Systems". NASA Johnson Space Center Technical Report. NASA/TM-2007-213740. Retrieved 2008-06-05.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  21. ^ US Navy Diving Manual, 6th revision. United States: US Naval Sea Systems Command. 2006. Retrieved 2008-04-24.
  22. ^ A position which it would formally maintain until in 1995 magazine editor Bill Gleason was reported to say that nitrox was "all right". Skin Diver would later go into bankruptcy.
  23. ^ TDI, Nitrox Gas Blending Manual, at pages 9-11
  24. ^ a b Allen, C (1996). "BSAC gives the OK to nitrox". Diver 1995; 40(5) May: 35-36. reprinted in South Pacific Underwater Medicine Society Journal. 26 (3). ISSN 0813-1988. OCLC 16986801. Retrieved 2008-05-02.
  25. ^ http://www.americandivecenter.com/nitrox/preview_p03.htm
  26. ^ R.A.BERNER AND D.E.CANFIELD (1989. A NEW MODEL FOR ATMOSPHERIC OXYGEN OVER PHANEROZOIC TIME. AMERICAN JOURNAL OF SCIENCE 289, pp.333-361.
  27. ^ ATMOSPHERIC OXYGEN, GIANT PALEOZOIC INSECTS AND THE EVOLUTION OF AERIAL LOCOMOTOR PERFORMANCE. ROBERT DUDLEY* Department of Zoology, University of Texas, Austin, TX 78712, USA and Smithsonian Tropical Research Institute, PO Box 2072, Balboa, Republic of Panama Accepted 28 October 1997; published on WWW 24 March 1998.

Footnotes

  1. ^ Oxygen has the potential to be 1.7 times more narcotic than nitrogen - see relevant narcotic potency of gases
  2. ^ Although oxygen appears chemically more narcotic at the surface, relative narcotic effects at depth have never been studied in detail. It is clear that different gases result in different narcotic effects at depth. Helium is considered to have very little narcotic effect, but results in HPNS when breathed at high pressures, which does not happen with gases with have greater narcotic qualities.