2-Fluorobenzoic acid

2-Fluorobenzoic acid
Names
	Preferred IUPAC name 2-Fluorobenzoic acid
	Other names o-Fluorobenzoic acid
Identifiers
CAS Number	445-29-4 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:19577 ;
ChEMBL	ChEMBL114383 ;
ChemSpider	9547 ;
ECHA InfoCard	100.006.509
KEGG	C02359 ;
PubChem CID	9935;
UNII	64UZ32KOO4 ;
CompTox Dashboard (EPA)	DTXSID1060001 ;
	InChI InChI=1S/C7H5FO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10) Key: NSTREUWFTAOOKS-UHFFFAOYSA-N;
	SMILES O=C(O)c1ccccc1F;
Properties
Chemical formula	C7H5FO2
Molar mass	140.113 g·mol−1
Melting point	126 °C (259 °F; 399 K)
log P	1.856
Acidity (pKa)	3.27
Hazards
Flash point	102 °C (216 °F; 375 K)
Safety data sheet (SDS)	Laboratory Chemical Safety Summary
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

2-Fluorobenzoic acid is an aromatic organic compound with the formula FC₆H₄CO₂H. It is one of three isomeric fluorobenzoic acids. Its conjugate base is 2-fluorobenzoate. The compound is an irritant.

Its metabolism has been studied extensively in the field of microbiology.^[1]^[2] Its conjugate base is part of the pathway of 2-fluorobiphenyl metabolism by Pseudomonas pseudoalcaligenes.

References

^ Milne, G. W. A.; P. Goldman; J. L. Holtzman (1968). "The metabolism of 2-fluorobenzoic acid. Studies with ¹⁸O₂". J. Biol. Chem. 243 (20): 5374–5376. doi:10.1016/S0021-9258(18)91959-9. PMID 5702050.
^ Murphy, Cormac D.; Quirke, Shane; Balogun, Olufunmilayo (2008). "Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenesKF707". FEMS Microbiology Letters. 286 (1): 45–9. doi:10.1111/j.1574-6968.2008.01243.x. PMID 18616594.

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[1] Milne, G. W. A.; P. Goldman; J. L. Holtzman (1968). "The metabolism of 2-fluorobenzoic acid. Studies with ¹⁸O₂". J. Biol. Chem. 243 (20): 5374–5376. doi:10.1016/S0021-9258(18)91959-9. PMID 5702050.

[2] Murphy, Cormac D.; Quirke, Shane; Balogun, Olufunmilayo (2008). "Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenesKF707". FEMS Microbiology Letters. 286 (1): 45–9. doi:10.1111/j.1574-6968.2008.01243.x. PMID 18616594.

[1]

[2]

See also

References