Cardamomin

Cardamomin
Names
	Preferred IUPAC name 2′,4′-Dihydroxy-6′-methoxychalcone
	Other names (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
Identifiers
CAS Number	19309-14-9 =;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL378104 ;
ChemSpider	557026 ;
ECHA InfoCard	100.189.861
PubChem CID	641785;
UNII	H8KP1OJ8JX ;
CompTox Dashboard (EPA)	DTXSID201029726 ;
	InChI InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+ Key: NYSZJNUIVUBQMM-BQYQJAHWSA-N ; InChI=1/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+ Key: NYSZJNUIVUBQMM-BQYQJAHWBN;
	SMILES COC1=CC(=CC(=C1C(=O)C=CC2=CC=CC=C2)O)O;
Properties
Chemical formula	C16H14O4
Molar mass	270.27 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Cardamomin (also known as cardamonin) is a chalconoid that has been isolated from several plants including Alpinia katsumadai^[1] and Alpinia conchigera.^[2] It has received growing attention from the scientific community due to the expectations toward its benefits to human health.^[3]

References

^ Kimura, Y.; Takahashi, S.; Yoshida, I. (1968). "Studies on the constituents of Alpinia. XII. On the constituents of the seeds of Alpinia katsumadai hayata. I. The structure of cardamomin". Yakugaku Zasshi. 88 (2): 239–241. doi:10.1248/yakushi1947.88.2_239. PMID 5692492.
^ Lee, J. -H.; Jung, H. S.; Giang, P. M.; Jin, X.; Lee, S.; Son, P. T.; Lee, D.; Hong, Y. S.; Lee, K.; Lee, J. J. (2005). "Blockade of Nuclear Factor- B Signaling Pathway and Anti-Inflammatory Activity of Cardamomin, a Chalcone Analog from Alpinia conchigera". Journal of Pharmacology and Experimental Therapeutics. 316 (1): 271–278. doi:10.1124/jpet.105.092486. PMID 16183703. S2CID 6069217.
^ Gonçalves, Luís Moreira (2014). "An Overview on Cardamonin". Journal of Medicinal Food. 17 (6): 633–640. doi:10.1089/jmf.2013.0061. PMC 4060836. PMID 24433078.

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[1] Kimura, Y.; Takahashi, S.; Yoshida, I. (1968). "Studies on the constituents of Alpinia. XII. On the constituents of the seeds of Alpinia katsumadai hayata. I. The structure of cardamomin". Yakugaku Zasshi. 88 (2): 239–241. doi:10.1248/yakushi1947.88.2_239. PMID 5692492.

[2] Lee, J. -H.; Jung, H. S.; Giang, P. M.; Jin, X.; Lee, S.; Son, P. T.; Lee, D.; Hong, Y. S.; Lee, K.; Lee, J. J. (2005). "Blockade of Nuclear Factor- B Signaling Pathway and Anti-Inflammatory Activity of Cardamomin, a Chalcone Analog from Alpinia conchigera". Journal of Pharmacology and Experimental Therapeutics. 316 (1): 271–278. doi:10.1124/jpet.105.092486. PMID 16183703. S2CID 6069217.

[3] Gonçalves, Luís Moreira (2014). "An Overview on Cardamonin". Journal of Medicinal Food. 17 (6): 633–640. doi:10.1089/jmf.2013.0061. PMC 4060836. PMID 24433078.

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v t e Chalconoids and their glycosides
Chalconoids	Butein Isoliquiritigenin Methyl hydroxychalcone Okanin
Chalconoid glycosides	Carthamin Marein okanin 3,4,3′-trimethyl ether 4′-glucoside okanin 4-methyl ether 4′-glucoside okanin 4-methyl ether 4′-glucoside monoacetate Okanin 3,4-dimethyl ether 4′-glucoside
Acylated chalconoids	Licochalcone A Sophoradin (prenylated) Tephrospinosin (3′,5′-diisopentenyl-2′,4′-dihydroxychalcone) (prenylated) Xanthohumol (prenylated)
O-methylated chalconoids	Cardamomin Flavokawin B Okanin 3,4,3′,4′-tetramethyl ether Pashanone (2',6'-Dihydroxy-3',4'-dimethoxychalcone)
Flavokavains	Flavokavain A Flavokavain B Flavokavain C
Synthetic	Sofalcone