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Iodopindolol

From Wikipedia, the free encyclopedia
Iodopindolol
Clinical data
Other names[125I]Iodopindolol; 3-Iodopindolol
Identifiers
  • (2S)-1-{[3-(125I)Iodo-1H-indol-4-yl]oxy}-3-(isopropylamino)-2-propanol
CAS Number
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H19IN2O2
Molar mass374.222 g·mol−1
3D model (JSmol)
  • CC(C)NC[C@@H](COc1cccc2c1c(c[nH]2)[125I])O
  • InChI=1S/C14H19IN2O2/c1-9(2)16-6-10(18)8-19-13-5-3-4-12-14(13)11(15)7-17-12/h3-5,7,9-10,16-18H,6,8H2,1-2H3/t10-/m0/s1/i15-2
  • Key:LOMQONAZKMLAOB-BDIJBZSESA-N

Iodopindolol is a beta-adrenergic selective antagonist tagged with radioactive iodine-125. It has been used to map beta receptors in cellular experiments.[1]

See also

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References

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  1. ^ Ezrailson EG, Garber AJ, Munson PJ, Swartz TL, Birnbaumer L, Entman ML (1981). "[125I]iodopindolol: a new beta adrenergic receptor probe". Journal of Cyclic Nucleotide Research. 7 (1): 13–26. PMID 6265511.