Sultan Eser

The Izmir cancer registry, the first population-based cancer registry in Turkey, was established in 1992. Cancer registration is now done by active methods. The registry contributed data on survival for 12 cancer sites or types registered in 1995-1997. Follow-up was predominantly done by active methods with median follow-up ranging between 17-72 months for different cancers. The proportion with histologically verified diagnosis for various cancers ranged between 84-100%; there were no death certificate only (DCO) cases; 98-100% of total registered cases were included for the survival analysis. Complete follow-up at five years ranged from 79-98% for different cancers. Five-year age-standardized relative survival rates of common cancers were breast (77%), urinary bladder (70%), Larynx (69%), colon (53%), rectum (52%), non-Hodgkin Lymphoma (50%) and cervix (58%). Five-year relative survival by age group portrayed decreasing survival with increasing age at diagnosis for cancer of the cervix, and was fluctuating for other cancers. Decreasing survival with increasing clinical extent of disease was also noted.

Purpose: To determine the psychometric properties of the Turkish version of the World Health Organization Quality of Life Instrument-Older Adults Module (WHOQOL-Old). Methods: The Turkish version of the WHOQOL-OLD was administered to 527 older (> 65 years) adults living in urban, suburban, and rural areas of Manisa Province, Turkey. The WHOQOL-OLD module consists of 24 items assigned to 6 facets (sen------sory abilities, autonomy, past, present and future activities, so-cial participation, death and dying, and intimacy) and is a supplementary module of WHOQOL-BREF. The WHOQOL-BREF and GDS-30 were also administered to the participants. A confirmatory approach was used during reliability and validity analysis. SPSS v.10.0 and LISREL v.8.54 were used for analysis. Results: Mean age of the participants was 71.06 +/- 5.20 years and the overall WHOQOL-OLD score was 56.02 +/- 11.86. In all, 54.5% of the participants were female and 60.5% reported to be in poor health. Both ceiling and floor effects of the WHOQOL-OLD were satisfactory (< 0.05%). Alpha values for the facets and overall scale (range: 0.68-0.88) (> 0.70), and item total correlations and overall scale success were satisfactory. As a measure of the construct validity of the scale, confirmatory factor analysis showed very high CFI values (range: 0.936-0.999) for each of the domains. Convergence of WHOQOL-OLD facet scores on WHOQOL-BREF domains and WHOQOL-OLD were very fine in general. Conclusions: The psychometric properties of the Turkish version of the WHOQOL-OLD were acceptable, indicating that the scale is reliable and valid for use with older Turkish adults (> 65 years).

... ve Veri Toplama Projesi veriyi daha etkin biçimde toplamak ve uluslararası bilim çevrelerinde kabul edilebilir olmaya izin verecek bir tamlık ve kalite düzeyine ulaştırmak doğrultusunda yeniden ... Şenay Mete, Tülay Yüksel, Emel Dalmızrak ve Tuğba Tıraş&amp;amp;#x27;a teşekkür ederiz. ...

Background: The Herat province of Afghanistan is located on the Asian Esophageal Cancer Belt (AECB), a wide area in Central and Eastern Asia where very high rates of esophageal cancer (EC) have been observed. Several risk factors have been reported in the AECB Region by previous studies. Considering lack of information in Afghanistan on this issue, a study was conducted to determine the major risk factors related to EC in order to guide protective measures. Methods: A population-based case-control study was performed from July 2015 to August 2016 among 657 EC patients in the Herat Province and 180 histopathological confirmed cases and 189 controls were interviewed. A structured questionnaire was used and face-to-face interviews were conducted. Results: Low body mass index (BMI), low socio-economic status, family history of EC, consumption of dark tea, very hot beverage and qulurtoroosh were found to be statistically significant for EC and esophageal squamous cell carcinoma (ESCC) in...

Giris ve Amac: Cevre kirliligi gun gectikce istenmedik boyutlara ulasmis, insan sagligina zararli hale gelmis ve dogal dengeyi hissedilir derecede bozmustur. Calismamizda Balikesir il merkezinde iki mahallede,18 yas uzeri bireylerde cevreyle ilgili bilgi, farkindalik, tutum ve davranis durumlarinin degerlendirilmesi ve iliskili faktorlerin saptanmasi amaclanmistir. Gerec ve Yontem: Kesitsel olarak planlanan bu calisma 04-15 Eylul 2019 doneminde, Balikesir’in merkez mahallelerinde yasayan 18 yas ve uzeri bireylerde yurutulmustur.  Ornek buyuklugu hesaplanirken, onceki calismalardan elde edilen cevre farkindaligi bilinci duzeyi %35 baz alinip, %5 sapma ve %95 guven duzeyi ile 10.023’luk evrenden 338 kisi hesaplanmis olup, 400 kiside calisma yurutulmustur. Calisma oncesi Balikesir Universitesi Tip Fakultesi’nden 2019/105 karar no’lu 28.08.2019 tarihli etik kurul izni alinmistir. Arastirmada cok asamali kume orneklem yontemi kullanilmistir. Kume buyuklugu 40 olarak belirlenmis olup, her...

GIRIŞ ve AMAC: Asi tereddudu son yillarda artan onemli bir halk sagligi sorunudur. Bu calismanin amaci Ebeveynlerin Cocukluk Asilarina Yonelik Tutumlari Olcegi’nin (PACV) Turkce surumunun psikometrik ozelliklerini saptamaktir. YONTEM ve GERECLER: Metodolojik tipteki bu calisma Ocak-Mayis 2019 tarihleri arasinda Balikesir Universitesi Saglik Uygulama ve Arastirma Hastanesi Cocuk Poliklinigine basvuran 0-59 aylik cocugu olan ebeveynlerle (n=211) gorusulerek yurutulmustur. PACV olcegi 15 sorudan, davranis, tutum, guvenlilik etkililik alt boyutlarindan olusmaktadir. Guvenilirlik analizlerinde ic tutarlilik (Cronbach’in alfa degeri kullanilarak), gecerlilik analizlerinde yapisal gecerlilik (bilinen gruplar ve dogrulayici faktor analizi) ve ayirt edici gecerlilik kullanilmistir. Dogrulayici faktor analizinde (DFA) Karsilastirilmali Uyum Indeksi (KUI-CFI) ve RMSEA’dan yararlanilmistir. Analizlerde “SPSS version 21.0 for Windows” ve Lisrel 8.54 istatistik paket programlari kullanilmistir. B...

Amac: Bu calismanin amaci Balikesir il merkezindeki iki aile sagligi merkezi (ASM) bolgesinde yasayan 0-14 yas cocugu olan ebeveynlerin asi tereddudu, asiya iliskin bilgi, tutum ve davranislari etkili faktorlerin degerlendirilmesidir. Gerec ve Yontem: Kesitsel tipteki calisma Aralik 2018-Ocak 2019 tarihleri arasinda Balikesir kent merkezindeki iki ASM bolgesinde yurutulmustur. Arastirmanin evrenini iki ASM’ye kayitli 0-14 yas cocugu olan 2950 kisi olusturmaktadir. Ornek buyuklugu Epiinfo programinda %10 prevalans %5 sapma, %95 guven duzeyi ve 2 desen etkisiyle 265 kisi hesaplanmis, 283 kisiye kume ornekleme yontemiyle ulasilmistir. Arastirmanin bagimli degiskenleri, asi hakkinda bilgi, asiya karsi tutum ve asi tereddudu bagimsiz degiskenler, sosyodemografik, saglik hizmet kullanimi, asiya iliskin ozelliklerden olusmaktadir. Anket formu literature dayali olusturulmus 5’li likert minimum 5, maksimum 25 puan alinabilen puan arttikca bilgi, tutum puanlarinin arttigi indekslerden olusmak...

Giris ve Amac: Asi tereddudu son yillarda artan onemli bir halk sagligi sorunudur. Bu calismanin amaci Ebeveynlerin Cocukluk Asilarina Iliskin Tutumlari (EAYT) Olcegi’nin gecerli, guvenilir olup olmadigini saptamaktir. Gerec ve Yontem: Metodolojik tipteki calisma Ocak-Mayis 2019 tarihleri arasinda Balikesir Universitesi Saglik Uygulama ve Arastirma Hastanesi Cocuk Poliklinigine basvuran 0-59 aylik cocugu olan ebeveynlerle (n=211) gorusulerek yurutulmustur. Opel ve ark. tarafindan gelistirilen (2011) ‘Cocukluk Cagi Asilarina Iliskin Ebeveynlerin Tutumlari’ olcegi 15 sorudan, uc alt boyuttan (davranis, tutum, guvenlilik etkililik) olusmaktadir. Puanlamada, tereddutlu yanitlara 2, ‘bilmiyorum ya da emin degilim’ yanitlarina 1, tereddutsuz yanitlara 0 puan verilerek elde edilen toplam puanlar 0-100 arasinda olmaktadir. Tanimlayici cozumlemelerde , ortalama, ortanca, standart sapma, carpiklik taban ve tavan yuzdeleri sunulmustur.  Guvenilirlik cozumlemelerinde “madde analizi” ve “ic tuta...

Ovarian cancers comprise several histologically distinct tumour groups with widely different prognosis. We aimed to describe the worldwide distribution of ovarian cancer histology and to understand what role this may play in international variation in survival. The CONCORD programme is the largest population-based study of global trends in cancer survival. Data on 681,759 women diagnosed during 1995-2009 with cancer of the ovary, fallopian tube, peritoneum and retroperitonum in 51 countries were included. We categorised ovarian tumours into six histological groups, and explored the worldwide distribution of histology. During 2005-2009, type II epithelial tumours were the most common. The proportion was much higher in Oceania (73.1%), North America (73.0%) and Europe (72.6%) than in Central and South America (65.7%) and Asia (56.1%). By contrast, type I epithelial tumours were more common in Asia (32.5%), compared with only 19.4% in North America. From 1995 to 2009, the proportion of...

BACKGROUND Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0-14 years) and adults (aged 15-99 years) diagnosed with a haematological malignancy during 2000-14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0-24 years). METHODS We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3 that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0-14 years), adolescents (15-19 years), and young adults (20-24 years). We categorised leukaemia subtypes according to the International Classification of Childhood Cancer (ICCC-3), updated with International Classification of Diseases for Oncology, third edition (ICD-O-3) codes. We estimated 5-year net survival by age and morphology, with 95% CIs, using the non-parametric Pohar-Perme estimator. To control for background mortality, we used life tables by country or region, single year of age, single calendar year and sex, and, where possible, by race or ethnicity. All-age survival estimates were standardised to the marginal distribution of young people with leukaemia included in the analysis. FINDINGS 164 563 young people were included in this analysis: 121 328 (73·7%) children, 22 963 (14·0%) adolescents, and 20 272 (12·3%) young adults. In 2010-14, the most common subtypes were lymphoid leukaemia (28 205 [68·2%] patients) and acute myeloid leukaemia (7863 [19·0%] patients). Age-standardised 5-year net survival in children, adolescents, and young adults for all leukaemias combined during 2010-14 varied widely, ranging from 46% in Mexico to more than 85% in Canada, Cyprus, Belgium, Denmark, Finland, and Australia. Individuals with lymphoid leukaemia had better age-standardised survival (from 43% in Ecuador to ≥80% in parts of Europe, North America, Oceania, and Asia) than those with acute myeloid leukaemia (from 32% in Peru to ≥70% in most high-income countries in Europe, North America, and Oceania). Throughout 2000-14, survival from all leukaemias combined remained consistently higher for children than adolescents and young adults, and minimal improvement was seen for adolescents and young adults in most countries. INTERPRETATION This study offers the first worldwide picture of population-based survival from leukaemia in children, adolescents, and young adults. Adolescents and young adults diagnosed with leukaemia continue to have lower survival than children. Trends in survival from leukaemia for adolescents and young adults are important indicators of the quality of cancer management in this age group. FUNDING Children with Cancer UK, the Institut National du Cancer, La Ligue Contre le Cancer, Centers for Disease Control and Prevention, Swiss Re, Swiss Cancer Research foundation, Swiss Cancer League, Rossy Family Foundation, US National Cancer Institute, and the American Cancer Society.

Objective: Cancers are the second most common cause of mortality following cardiovascular diseases in Turkey. Tobacco and obesity are the two major etiological factors for cancer progression, which are highly prevalent in Turkey. This study aimed to evaluate the new cancer cases in Turkey attributable to these two main risk factors. Material and methods: The tobacco-related cancers based on the International Agency for Research on Cancer (IARC) monographs were esophagus, oral cavity, gastric, pancreatic, larynx, lung, renal, and bladder cancers, and the obesity-related cancers based on the IARC&#39;s and World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) Continuous Update Project&#39;s reports were esophagus, colon, rectum, gallbladder, pancreas, kidney, ovary, endometrium, and breast cancers. The cancer incidences were obtained from the national cancer statistics. A lag time of at least 10 years was regarded adequate to observe the effects of past expos...

The purpose of this study is to provide a detailed report on cancer incidence in Turkey, a relatively large country with a population of 72 million. We present the estimates of the cancer burden in Turkey for 2006, calculated using data from the eight population based cancer registries which have been set up in selected provinces representative of sociodemographic patterns in their regions. We calculated age specific and age adjusted incidence rates (AAIR-world standard population) for each of registries separately. We assigned a weighting coefficient for each registry proportional to the population size of the region which the registry represents. We pooled a total of 24,428 cancers (14,581 males, 9,847 females). AAIRs per 100 000 were: 210.1 in men and 129.4 in women for all cancer sites excluding non-melanoma skin cancer. The AAIR per 100 000 men was highest for lung cancer (60.3) followed by prostate (22.8), bladder (19.6), stomach (16.3) and colo-rectal (15.4) cancers. Among wo...

There is a relative lack of epidemiological data on cancer in Turkey, which is a large country with its 71 million population, since there was not any population-based registry functioning in the country before Izmir Cancer Registry (ICR), which was founded in 1992. The present study focused on the incidence of cancers of the genitourinary tract in Izmir province over a ten year period to cover the gap in this kind of epidemiological data for this part of the world. ICR is a population-based registry which collects data actively and is running international registration rules during procedures. We evaluated the data for 1993-2002. Annual crude and age-standardized incidence rates were calculated for the whole period and also for earlier and later periods. The age-standardized incidence rate (world population) for all sites was 198.3 per 100,000 for males and 116.4 per 100,000 for females. The most common primary sites for men were lung (35.6%), bladder (7.8%), colon and rectum (6.1%...

Giris ve Amac: Bu calismada, Balikesir il merkezinde yasayan 18 yas ve uzeri kisilerin saglik algisi ile saglikli yasam bicimi davranislari (SYBD) duzeyi ve bunlarla iliskili olabilecek degiskenleri belirlemek amaciyla yapilmistir. Gerec ve Yontem: Kesitsel olarak planlanan bu calisma Eylul 2019 doneminde, Balikesir’in merkez mahallelerinde yasayan 18 yas ve uzeri bireylerde yurutulmustur.  Ornek buyuklugu hesaplanirken, calismada birden fazla bagimli oldugundan%50’lik prealans alinip, %5 sapma ve %95 guven duzeyi ile 56.150’lik evrenden 382 kisi hesaplanmis olup, 401 kiside calisma yurutulmustur. Calisma oncesi Balikesir Universitesi Tip Fakultesi’nden 2019/106 karar no’lu 28.08.2019 tarihli etik kurul izni alinmistir. Arastirmada cok asamali kume orneklem yontemi kullanilmistir. Sekiz kisiden olusan intorn ekibi, luterature dayali onceden olusturulmus anket formu kullanarak, yuz yuze gorusme teknigi ile veri toplamislardir. Calismanin bagimli degiskenlerini saglik algisi olcegi to...

To describe epidemiologic patterns of childhood (0-14 years) lymphomas in the Southern and Eastern European (SEE) region in comparison with the Surveillance, Epidemiology and End Results (SEER), USA, and explore tentative discrepancies. Childhood lymphomas were retrieved from 14 SEE registries (n = 4,702) and SEER (n = 4,416), diagnosed during 1990-2014; incidence rates were estimated and time trends were evaluated. Overall age-adjusted incidence rate was higher in SEE (16.9/10(6)) compared to SEER (13.6/10(6)), because of a higher incidence of Hodgkin (HL, 7.5/10(6) vs. 5.1/10(6)) and Burkitt lymphoma (BL, 3.1 vs. 2.3/10(6)), whereas the incidence of non-Hodgkin lymphoma (NHL) was overall identical (5.9/10(6) vs. 5.8/10(6)), albeit variable among SEE. Incidence increased with age, except for BL which peaked at 4 years; HL in SEE also showed an early male-specific peak at 4 years. The male preponderance was more pronounced for BL and attenuated with increasing age for HL. Increasing trends were noted in SEER for total lymphomas and NHL, and was marginal for HL, as contrasted to the decreasing HL and NHL trends generally observed in SEE registries, with the exception of increasing HL incidence in Portugal; of note, BL incidence trend followed a male-specific increasing trend in SEE. Registry-based data reveal variable patterns and time trends of childhood lymphomas in SEE and SEER during the last decades, possibly reflecting diverse levels of socioeconomic development of the populations in the respective areas; optimization of registration process may allow further exploration of molecular characteristics of disease subtypes.

Childhood (0-14 years) lymphomas, nowadays, present a highly curable malignancy compared with other types of cancer. We used readily available cancer registration data to assess mortality and survival disparities among children residing in Southern-Eastern European (SEE) countries and those in the United States. Average age-standardized mortality rates and time trends of Hodgkin (HL) and non-Hodgkin (NHL; including Burkitt [BL]) lymphomas in 14 SEE cancer registries (1990-2014) and the Surveillance, Epidemiology, and End Results Program (SEER, United States; 1990-2012) were calculated. Survival patterns in a total of 8918 cases distinguishing also BL were assessed through Kaplan-Meier curves and multivariate Cox regression models. Variable, rather decreasing, mortality trends were noted among SEE. Rates were overall higher than that in SEER (1.02/10(6) ), which presented a sizeable (-4.8%, P = .0001) annual change. Additionally, remarkable survival improvements were manifested in SEER (10 years: 96%, 86%, and 90% for HL, NHL, and BL, respectively), whereas diverse, still lower, rates were noted in SEE. Non-HL was associated with a poorer outcome and an amphi-directional age-specific pattern; specifically, prognosis was inferior in children younger than 5 years than in those who are 10 to 14 years old from SEE (hazard ratio 1.58, 95% confidence interval 1.28-1.96) and superior in children who are 5 to 9 years old from SEER/United States (hazard ratio 0.63, 95% confidence interval 0.46-0.88) than in those who are 10 to 14 years old. In conclusion, higher SEE lymphoma mortality rates than those in SEER, but overall decreasing trends, were found. Despite significant survival gains among developed countries, there are still substantial geographic, disease subtype-specific, and age-specific outcome disparities pointing to persisting gaps in the implementation of new treatment modalities and indicating further research needs.

Pilocytic astrocytomas (PA) comprise the most common childhood central nervous system (CNS) tumor. Exploiting registry-based data from Southern and Eastern Europe (SEE) and SEER, US, we opted to examine incidence, time trends, survival and tentative outcome disparities of childhood PA by sociodemographic and clinical features. Childhood PA were retrieved from 12 SEE registries (N = 552; 1983-2014) and SEER (N = 2723; 1973-2012). Age-standardized incidence rates (ASR) were estimated and survival was examined via Kaplan-Meier and Cox regression analysis. ASR of childhood PA during 1990-2012 in SEE was 4.2/10(6), doubling in the USA (8.2/10(6)). Increasing trends, more prominent during earlier registration years, were recorded in both areas (SEE: +4.1 %, USA: +4.6 %, annually). Cerebellum comprised the most common location, apart from infants in whom supratentorial locations prevailed. Age at diagnosis was 1 year earlier in SEE, whereas 10-year survival was 87 % in SEE and 96 % in SEER, improving over time. Significant outcome predictors were age &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;1 year at diagnosis diagnosis (hazard ratio, HR [95% confidence intervals]: 3.96, [2.28-6.90]), female gender (HR: 1.38, [1.01-1.88]), residence in SEE (HR: 4.07, [2.95-5.61]) and rural areas (HR: 2.23, [1.53-3.27]), whereas non-cerebellar locations were associated with a 9- to 12-fold increase in risk of death. The first comprehensive overview of childhood PA epidemiology showed survival gains but also outcome discrepancies by geographical region and urbanization pointing to healthcare inequalities. The worse prognosis of infants and, possibly, females merits further consideration, as it might point to treatment adjustment needs, whereas expansion of systematic registration will allow interpretation of incidence variations.

To assess trends in survival and geographic disparities among children (0-14 years) with chronic myeloid leukaemia (CML) before and after the introduction of molecular therapy, namely tyrosine kinase inhibitors (TKIs) in Southern-Eastern European (SEE) countries and the USA. We calculated survival among children with CML, acute lymphoblastic (ALL) and acute myeloid leukaemia (AML) in 14 SEE (1990-2014) cancer registries and the U.S. Surveillance, Epidemiology and End Results Program (SEER, 1990-2012). We used Kaplan-Meier curves and multivariate Cox regression models to calculate hazard ratios (HRs) with 95% confidence intervals (CIs). Among 369 CML cases, substantial improvements were noted in 2-year survival during the post-TKI (range: 81-89%) compared to pre-TKI period (49-66%; HR: 0.37, 95% CI: 0.23-0.60). Risk of death was three times higher for &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;5-year-old children versus those aged 10-14 years (HR: 3.03, 95% CI: 1.85-4.94) and 56% higher for those living in SEE versus SEER (HR: 1.56, 95% CI: 1.01-2.42). Regardless of geographic area and period of TKI administration, however, age seems to be a significant determinant of CML prognosis (pre-TKI period, HR0-4y: 2.71, 95% CI: 1.53-4.79; post-TKI period, HR0-4y: 3.38, 95% CI: 1.29-8.85). Noticeably, post-TKI survival in CML overall approximates that for ALL, whereas therapeutic advancements for AML remain modest. Registry data show that introduction of molecular therapies coincides with revolutionised therapeutic outcomes in childhood CML entailing dramatically improved survival which is now similar to that in ALL. Given that age disparities in survival remain substantial, offering optimal therapy to entire populations is an urgent priority.

Childhood central nervous system (CNS) tumour registration and control programs in Southern and Eastern Europe remain thin, despite the lethal nature of the disease. Mortality/survival data were assembled to estimate the burden of malignant CNS tumours, as well as the potential role of sociodemographic survival determinants across 14 cancer registries of this region. Average age-adjusted mortality rates were calculated, whereas time trends were quantified through Poisson and Joinpoint regressions. Kaplan-Meier curves were derived for the maximum and the more recent (10 and 5year) registration periods. Multivariate Cox regression models were used to assess demographic and disease-related determinants. Variations in mortality (8-16 per million) and survival (5-year: 35-69%) were substantial among the participating registries; in most registries mortality trend was stable, whereas Bulgaria, having the highest starting rate, experienced decreasing annual mortality (-2.4%, p=0.001). A steep decrease in survival rates was evident before the second year of follow-up. After controlling for diagnostic subgroup, age, gender and diagnostic year, Greece seemed to present higher survival compared with the other contributing registries, although the follow-up period was short. Irrespective of country, however, rural residence was found to impose substantial adverse repercussions on survival (hazard ratio (HR): 1.2, 95% confidence interval (CI): 1.1-1.4). Cross-country mortality and survival variations possibly reflect suboptimal levels of health care delivery and cancer control in some regions of Southern and Eastern Europe, notwithstanding questionable death certification patterns or follow-up procedures. Continuous childhood cancer registration and linkage with clinical data are prerequisite for the reduction of survival inequalities across Europe.

Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control. Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75 000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standar...

... Eds. Curado MP, Edwards B, Shin HR, Storm H, Ferlay J, Heanue M, Boyle P. IARC Scientific Publications No: 160, Lyon, France: International Agency for ... Türkiye&#x27;de yapılan bir çalışmada ise tüketile-tilen miktarla orantılı olarak kahve ve alko-lün riski artırdığı belirlenmiştir (38) ...

BACKGROUND There is a relative lack of epidemiological data on cancer in Turkey, which is a large country with its 71 million population, since there was not any population-based registry functioning in the country before Izmir Cancer Registry (ICR), which was founded in 1992. The present study focused on the incidence of cancers of the genitourinary tract in Izmir province over a ten year period to cover the gap in this kind of epidemiological data for this part of the world. METHODS ICR is a population-based registry which collects data actively and is running international registration rules during procedures. We evaluated the data for 1993-2002. Annual crude and age-standardized incidence rates were calculated for the whole period and also for earlier and later periods. RESULTS The age-standardized incidence rate (world population) for all sites was 198.3 per 100,000 for males and 116.4 per 100,000 for females. The most common primary sites for men were lung (35.6%), bladder (7....

PURPOSE The purpose of this study is to provide a detailed report on cancer incidence in Turkey, a relatively large country with a population of 72 million. We present the estimates of the cancer burden in Turkey for 2006, calculated using data from the eight population based cancer registries which have been set up in selected provinces representative of sociodemographic patterns in their regions. METHODS We calculated age specific and age adjusted incidence rates (AAIR-world standard population) for each of registries separately. We assigned a weighting coefficient for each registry proportional to the population size of the region which the registry represents. RESULTS We pooled a total of 24,428 cancers (14,581 males, 9,847 females). AAIRs per 100 000 were: 210.1 in men and 129.4 in women for all cancer sites excluding non-melanoma skin cancer. The AAIR per 100 000 men was highest for lung cancer (60.3) followed by prostate (22.8), bladder (19.6), stomach (16.3) and colo-rectal ...

Introduction: This study was carried out for psychometric analysis of the Turkish version of the WHO – Atittudes of Aging Questionnaire (AAQ). Materials and Method: AAQ consists of 24 items classified in three domains (Psychosocial Loss-PL; Physical Change-PC and Psychological Growth-PG) with 8 items each (min8 max40). Turkish centre results are presented in this EU FP 5th funded international project (n=833). Internal consistency analysis, Construct validity, Convergent Divergent validity and Known Groups validity were used. Results: 38.7 % of the sample was male, with a mean age 72.7± 6.1. Alpha values of the domains PL, PC ve PG were 0.75, 0.74 and 0.62 respectively. 7th item of the PC and 4th item of the PG violate the internal consistency. BD was the most affected domain by income and objective health (ES=0.50). PL and PC scores were higher among married and who received support(p&gt;0.05). CFA resulted acceptable fit for PC domain (RMESEA= 0.09;CFI=0.93); borderline for PC dom...

Ozet Amac: Calismanin amaci Turkiye’de yasli nufusta gozlenen kanser insidans hizlarindaki dususu irdelemektir.  Yontem: Bu calismada Bes Kitada Kanser Gorulusu, IX (Cancer Incidence in Five Continents, IX)’da yayimlanmis olan Izmir ve Antalya illerinde 1998-2002 yillarinda saptanan yasa ozel kanser insidans hizlari degerlendirildi. Bulgular: Izmir ve Antalya illerinde tum kanserler icin ve hemen her kanser icin 64 yas uzerindeki gruplarda her iki cinsiyette de yasa ozel insidans hizlarinda belirgin dusus egimi gorulmektedir. Sonuc: Turkiye’de yasli gruplarin insidans hizlarinda, pek cok kanser icin belirgin dususler soz konusudur. Oysa gercekte pek cok epitelyal kanserde insidans hizi yasla birlikte artar. Izmir ve Antalya’da gelismekte olan diger ulkelerdekine benzer sekilde gozlenen bu oruntuyu aciklamak icin uc varsayimdan sozedebiliriz: 1. Yaslilarin uygun saglik hizmetlerine ulasmalarindaki eksiklik (tani konmasindaki azlik), 2. Kohort etkisi, 3. Sagkalim yanilgisi. Turkiye’de...