Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het onderne... more Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernemerschap in de agrarische sector te versterken, met speciale aandacht voor de versterking van netwerkcompetenties' is in vier stappen uitgewerkt. Allereerst is een theoretische verkenning uitgevoerd rond ondernemerschap(scompetenties), strategisch management en het netwerken. Vervolgens zijn diepte-interviews gehouden en is een uitgebreide interventiestudie uitgevoerd. Ten slotte zijn de ervaringen bij de opzet en uitvoering èn de bevindingen bediscussieerd met vertegenwoordigers van adviesorganisaties en kennisinstellingen. The aim of the project 'the development and testing of intervention trajectories aimed at strengthening entrepreneurship in the agricultural sector, with special focus on strengthening networking competences' was developed in four steps. First of all, a theoretical study was conducted into entrepreneurship and entrepreneurial competences, strategic man...
The Dutch flower bulb industry is highly dynamic. From 1990 to 2003 the number of enterprises was... more The Dutch flower bulb industry is highly dynamic. From 1990 to 2003 the number of enterprises was reduced by 33%, farm size increased by 50%. The increase of scale reduced production costs per unit, of which costs of labor are the most important. The demand for environmental protection and improved working conditions also affects the production systems. System Innovation research programs were designed to stimulate new developments. In this context radical changes took place in the bulbous flower production systems, which resulted in cleaner (both environmentally and in working conditions), as well as in more efficient bulb flower production. The use of energy per unit was strongly reduced. Intensive cooperation and exchange between various stakeholders in the industry, research and extension, has contributed to a large extent to these rapid developments. This paper describes the underlying system component developments and future expectations. THE DUTCH FLOWER BULB INDUSTRY In the Dutch flower bulb industry, three main types of primary producers can be distinguished: a) bulb growers, b) growers of both flower bulbs in the field and bulbous flowers in the greenhouse and c) ornamental crop growers who include bulbous flower production in their greenhouse cropping system. The numbers of enterprises of the former two types are approximately equal, but cropped area of type-a is almost twice as big as type-b (Wildschut, 2004, unpublished data). The number of type-c enterprises is substantial, but not exactly known. Apart from primary producers, of which most are members of horticultural organizations, the industry consists of various stakeholders such as suppliers of inputs, machineries, automated systems, etc., of exporters and trading companies and of privatised research and extension services.
Using in vivo proton-magnetic resonance spectroscopy (1H-MRS), which allows the measurement of me... more Using in vivo proton-magnetic resonance spectroscopy (1H-MRS), which allows the measurement of metabolites of adequate tissue concentration, the origin of lactate in peritumoral edema has been assessed by comparison with lactate levels in the central and marginal areas of the tumor in 18 patients with cerebral gliomas. In the majority of cases lactate content in the area of peritumoral edema was lower than that in the tumor margin or tumor center, which is consistent with the assumption that the tumor is the source of lactate, which then reaches the surrounding area of edema by diffusion. In 3 of the 18 cases the amount of lactate in the peritumoral edematous tissue was higher than in the tumor, indicating that the lactate is locally produced on account of ischemia due to regional elevation of tissue pressure in the edematous area.
In this study, three-dimensional Fourier transformation constructive interference in steady state... more In this study, three-dimensional Fourier transformation constructive interference in steady state (3DFT-CISS) magnetic resonance imaging was used to quantify the distance between the vertical part of the posterior semicircular canal and the posterior fossa as a measure of the endolymphatic sac and duct in patients with Menière's disease. Differences in this distance between affected and unaffected ears, as well as differences between unilaterally and bilaterally affected patients, were studied and compared with a control group. Also, possible correlations between the measured distance and the duration and severity of symptoms, patient age, and average hearing loss were investigated in the group of patients with Menière's disease. Retrospective clinical study. Tertiary referral center (University Hospital) as part of a large, diagnostic research project on Menière's disease. Of the 111 patients with Menière's disease initially included, 90 patients underwent 3DFT-CISS MRI. Eighty-six of these patients were analyzed in this MRI study. Fifty-six patients had unilateral Menière's disease, and 30 patients had bilateral Menière's disease (116 affected and 56 unaffected ears). Sixty-two ears in patients without Menière's disease were studied as controls. The distance between the vertical part of the posterior semicircular canal and the posterior fossa was determined by 3DFT-CISS MRI. Contiguous axial 3DFT-CISS MRI slices of 0.7 to 1.0 mm were made by a radiologist according to a strict protocol. Measurements of the distance between the vertical part of the posterior semicircular canal and the posterior fossa were taken by two professionals-a radiologist and an otolaryngologist-using a ruler and the original scan. A significantly smaller distance (2.9 mm) between the vertical part of the posterior semicircular canal and the posterior fossa as visualized on MRI scans was found in the ears of patients with Menière's disease than in the ears of patients in the control group (3.8 mm, p < 0.001). In both uni- and bilaterally affected patients (n = 56 and n = 30, respectively), no significant difference between ears was found (p = 0.44 and p = 0.19, respectively). In bilaterally affected patients, however, this distance (3.2 mm) was significantly greater than the distance in unilaterally affected patients (2.7 mm, p = 0.004). There was no relationship between the MRI-visualized distance between the vertical part of the posterior semicircular canal and the posterior fossa and the duration of disease, average hearing loss, or severity of symptoms in uni- and bilaterally affected patients. The difference in MRI-visualized distances between the vertical part of the posterior semicircular canal and the posterior fossa of uni- and bilaterally affected patients strongly suggests that unilateral and bilateral hearing loss are two different entities in patients with Menière's disease. The size of the endolymphatic sac seems not to be the only factor in the pathogenesis of Menière's disease. That the MRI-visualized distance between the vertical part of the posterior semicircular canal and the posterior fossa does not have any relationship to the duration of the disease or to patient age indicates that this distance is a congenital feature.
Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernem... more Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernemerschap in de agrarische sector te versterken, met speciale aandacht voor de versterking van netwerkcompetenties' is in vier stappen uitgewerkt. Allereerst is een theoretische verkenning uitgevoerd rond ondernemerschap(scompetenties), strategisch management en het netwerken. Vervolgens zijn diepte-interviews gehouden en is een uitgebreide interventiestudie uitgevoerd. Ten slotte zijn de
Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het onderne... more Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernemerschap in de agrarische sector te versterken, met speciale aandacht voor de versterking van netwerkcompetenties' is in vier stappen uitgewerkt. Allereerst is een theoretische verkenning uitgevoerd rond ondernemerschap(scompetenties), strategisch management en het netwerken. Vervolgens zijn diepte-interviews gehouden en is een uitgebreide interventiestudie uitgevoerd. Ten slotte zijn de ervaringen bij de opzet en uitvoering èn de bevindingen bediscussieerd met vertegenwoordigers van adviesorganisaties en kennisinstellingen. The aim of the project 'the development and testing of intervention trajectories aimed at strengthening entrepreneurship in the agricultural sector, with special focus on strengthening networking competences' was developed in four steps. First of all, a theoretical study was conducted into entrepreneurship and entrepreneurial competences, strategic man...
Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het onderne... more Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernemerschap in de agrarische sector te versterken, met speciale aandacht voor de versterking van netwerkcompetenties' is in vier stappen uitgewerkt. Allereerst is een theoretische verkenning uitgevoerd rond ondernemerschap(scompetenties), strategisch management en het netwerken. Vervolgens zijn diepte-interviews gehouden en is een uitgebreide interventiestudie uitgevoerd. Ten slotte zijn de ervaringen bij de opzet en uitvoering èn de bevindingen bediscussieerd met vertegenwoordigers van adviesorganisaties en kennisinstellingen. The aim of the project 'the development and testing of intervention trajectories aimed at strengthening entrepreneurship in the agricultural sector, with special focus on strengthening networking competences' was developed in four steps. First of all, a theoretical study was conducted into entrepreneurship and entrepreneurial competences, strategic man...
The Dutch flower bulb industry is highly dynamic. From 1990 to 2003 the number of enterprises was... more The Dutch flower bulb industry is highly dynamic. From 1990 to 2003 the number of enterprises was reduced by 33%, farm size increased by 50%. The increase of scale reduced production costs per unit, of which costs of labor are the most important. The demand for environmental protection and improved working conditions also affects the production systems. System Innovation research programs were designed to stimulate new developments. In this context radical changes took place in the bulbous flower production systems, which resulted in cleaner (both environmentally and in working conditions), as well as in more efficient bulb flower production. The use of energy per unit was strongly reduced. Intensive cooperation and exchange between various stakeholders in the industry, research and extension, has contributed to a large extent to these rapid developments. This paper describes the underlying system component developments and future expectations. THE DUTCH FLOWER BULB INDUSTRY In the Dutch flower bulb industry, three main types of primary producers can be distinguished: a) bulb growers, b) growers of both flower bulbs in the field and bulbous flowers in the greenhouse and c) ornamental crop growers who include bulbous flower production in their greenhouse cropping system. The numbers of enterprises of the former two types are approximately equal, but cropped area of type-a is almost twice as big as type-b (Wildschut, 2004, unpublished data). The number of type-c enterprises is substantial, but not exactly known. Apart from primary producers, of which most are members of horticultural organizations, the industry consists of various stakeholders such as suppliers of inputs, machineries, automated systems, etc., of exporters and trading companies and of privatised research and extension services.
Using in vivo proton-magnetic resonance spectroscopy (1H-MRS), which allows the measurement of me... more Using in vivo proton-magnetic resonance spectroscopy (1H-MRS), which allows the measurement of metabolites of adequate tissue concentration, the origin of lactate in peritumoral edema has been assessed by comparison with lactate levels in the central and marginal areas of the tumor in 18 patients with cerebral gliomas. In the majority of cases lactate content in the area of peritumoral edema was lower than that in the tumor margin or tumor center, which is consistent with the assumption that the tumor is the source of lactate, which then reaches the surrounding area of edema by diffusion. In 3 of the 18 cases the amount of lactate in the peritumoral edematous tissue was higher than in the tumor, indicating that the lactate is locally produced on account of ischemia due to regional elevation of tissue pressure in the edematous area.
In this study, three-dimensional Fourier transformation constructive interference in steady state... more In this study, three-dimensional Fourier transformation constructive interference in steady state (3DFT-CISS) magnetic resonance imaging was used to quantify the distance between the vertical part of the posterior semicircular canal and the posterior fossa as a measure of the endolymphatic sac and duct in patients with Menière's disease. Differences in this distance between affected and unaffected ears, as well as differences between unilaterally and bilaterally affected patients, were studied and compared with a control group. Also, possible correlations between the measured distance and the duration and severity of symptoms, patient age, and average hearing loss were investigated in the group of patients with Menière's disease. Retrospective clinical study. Tertiary referral center (University Hospital) as part of a large, diagnostic research project on Menière's disease. Of the 111 patients with Menière's disease initially included, 90 patients underwent 3DFT-CISS MRI. Eighty-six of these patients were analyzed in this MRI study. Fifty-six patients had unilateral Menière's disease, and 30 patients had bilateral Menière's disease (116 affected and 56 unaffected ears). Sixty-two ears in patients without Menière's disease were studied as controls. The distance between the vertical part of the posterior semicircular canal and the posterior fossa was determined by 3DFT-CISS MRI. Contiguous axial 3DFT-CISS MRI slices of 0.7 to 1.0 mm were made by a radiologist according to a strict protocol. Measurements of the distance between the vertical part of the posterior semicircular canal and the posterior fossa were taken by two professionals-a radiologist and an otolaryngologist-using a ruler and the original scan. A significantly smaller distance (2.9 mm) between the vertical part of the posterior semicircular canal and the posterior fossa as visualized on MRI scans was found in the ears of patients with Menière's disease than in the ears of patients in the control group (3.8 mm, p < 0.001). In both uni- and bilaterally affected patients (n = 56 and n = 30, respectively), no significant difference between ears was found (p = 0.44 and p = 0.19, respectively). In bilaterally affected patients, however, this distance (3.2 mm) was significantly greater than the distance in unilaterally affected patients (2.7 mm, p = 0.004). There was no relationship between the MRI-visualized distance between the vertical part of the posterior semicircular canal and the posterior fossa and the duration of disease, average hearing loss, or severity of symptoms in uni- and bilaterally affected patients. The difference in MRI-visualized distances between the vertical part of the posterior semicircular canal and the posterior fossa of uni- and bilaterally affected patients strongly suggests that unilateral and bilateral hearing loss are two different entities in patients with Menière's disease. The size of the endolymphatic sac seems not to be the only factor in the pathogenesis of Menière's disease. That the MRI-visualized distance between the vertical part of the posterior semicircular canal and the posterior fossa does not have any relationship to the duration of the disease or to patient age indicates that this distance is a congenital feature.
Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernem... more Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernemerschap in de agrarische sector te versterken, met speciale aandacht voor de versterking van netwerkcompetenties' is in vier stappen uitgewerkt. Allereerst is een theoretische verkenning uitgevoerd rond ondernemerschap(scompetenties), strategisch management en het netwerken. Vervolgens zijn diepte-interviews gehouden en is een uitgebreide interventiestudie uitgevoerd. Ten slotte zijn de
Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het onderne... more Het doel van het project 'het ontwikkelen en toetsen van interventietrajecten om het ondernemerschap in de agrarische sector te versterken, met speciale aandacht voor de versterking van netwerkcompetenties' is in vier stappen uitgewerkt. Allereerst is een theoretische verkenning uitgevoerd rond ondernemerschap(scompetenties), strategisch management en het netwerken. Vervolgens zijn diepte-interviews gehouden en is een uitgebreide interventiestudie uitgevoerd. Ten slotte zijn de ervaringen bij de opzet en uitvoering èn de bevindingen bediscussieerd met vertegenwoordigers van adviesorganisaties en kennisinstellingen. The aim of the project 'the development and testing of intervention trajectories aimed at strengthening entrepreneurship in the agricultural sector, with special focus on strengthening networking competences' was developed in four steps. First of all, a theoretical study was conducted into entrepreneurship and entrepreneurial competences, strategic man...
Uploads
Papers by A.T. Krikke