ABSTRACT Peer learning can play an important role in the transformation of undergraduate and grad... more ABSTRACT Peer learning can play an important role in the transformation of undergraduate and graduate science, technology, engineering and math (STEM) courses from passive to active learning environments. We present a mixed method study exploring the effect of two peer teaching programs at a research university: the Learning Assistant program and the Undergraduate Assistant program. Study results show benefits for the peer teachers and the undergraduates in the courses. Additionally, the peer teachers can provide an important feedback loop for professors, teaching fellows, and course administrators, thereby enabling pedagogical changes within the same semester. A more intense approach to peer teacher training, ongoing support, and higher levels of assigned responsibility for peer teachers are associated with more positive outcomes for the peer teachers and STEM courses.
Description of a multiscale simulation strategy we have developed to attack problems of RNA catal... more Description of a multiscale simulation strategy we have developed to attack problems of RNA catalysis is presented. Ribozyme systems give special challenges not present in typical protein systems, and consequently demand new methods. The main methodological ...
... in particular Dr. Kevin Range and Dr. Tim Giese. To my collaborators at the Uni-versity of Mi... more ... in particular Dr. Kevin Range and Dr. Tim Giese. To my collaborators at the Uni-versity of Minnesota Masonic Cancer Center, Rebecca Guza, Uthpala Seneviratne, and Dr. Natalia Tretyakova. Susan Ballinger, who started me on this path. Professor Scott ...
Five multilevel model chemistries (CBS-QB3, G3B3, G3MP2B3, MCG3/3, and MC-QCISD/3) and seven hybr... more Five multilevel model chemistries (CBS-QB3, G3B3, G3MP2B3, MCG3/3, and MC-QCISD/3) and seven hybrid density functional methods (PBE0, B1B95, B3LYP, MPW1KCIS, PBE1KCIS, and MPW1B95) have been applied to the calculation of gas-phase basicity and proton affinity values for a series of 17 molecules relevant to the study of biological phosphoryl transfer. In addition, W1 calculations were performed on a subset of molecules. The accuracy of the methods was assessed and the nature of systematic errors was explored, leading to the introduction of a set of effective bond enthalpy and entropy correction terms. The multicoefficient correlation methods (MCG3/3 and MC-QCISD), with inclusion of specific zero-point scale factors, slightly outperform the other multilevel methods tested (CBS-QB3, G3B3, and G3MP2B3), with significantly less computational cost, and in the case of MC-QCISD, slightly less severe scaling. Four density functional methods, PBE1KCIS, MPW1B95, PBE0, and B1B95 perform nearly as well as the multilevel methods. These results provide an important set of benchmarks relevant to biological phosphoryl transfer reactions.
ABSTRACT Peer learning can play an important role in the transformation of undergraduate and grad... more ABSTRACT Peer learning can play an important role in the transformation of undergraduate and graduate science, technology, engineering and math (STEM) courses from passive to active learning environments. We present a mixed method study exploring the effect of two peer teaching programs at a research university: the Learning Assistant program and the Undergraduate Assistant program. Study results show benefits for the peer teachers and the undergraduates in the courses. Additionally, the peer teachers can provide an important feedback loop for professors, teaching fellows, and course administrators, thereby enabling pedagogical changes within the same semester. A more intense approach to peer teacher training, ongoing support, and higher levels of assigned responsibility for peer teachers are associated with more positive outcomes for the peer teachers and STEM courses.
Description of a multiscale simulation strategy we have developed to attack problems of RNA catal... more Description of a multiscale simulation strategy we have developed to attack problems of RNA catalysis is presented. Ribozyme systems give special challenges not present in typical protein systems, and consequently demand new methods. The main methodological ...
... in particular Dr. Kevin Range and Dr. Tim Giese. To my collaborators at the Uni-versity of Mi... more ... in particular Dr. Kevin Range and Dr. Tim Giese. To my collaborators at the Uni-versity of Minnesota Masonic Cancer Center, Rebecca Guza, Uthpala Seneviratne, and Dr. Natalia Tretyakova. Susan Ballinger, who started me on this path. Professor Scott ...
Five multilevel model chemistries (CBS-QB3, G3B3, G3MP2B3, MCG3/3, and MC-QCISD/3) and seven hybr... more Five multilevel model chemistries (CBS-QB3, G3B3, G3MP2B3, MCG3/3, and MC-QCISD/3) and seven hybrid density functional methods (PBE0, B1B95, B3LYP, MPW1KCIS, PBE1KCIS, and MPW1B95) have been applied to the calculation of gas-phase basicity and proton affinity values for a series of 17 molecules relevant to the study of biological phosphoryl transfer. In addition, W1 calculations were performed on a subset of molecules. The accuracy of the methods was assessed and the nature of systematic errors was explored, leading to the introduction of a set of effective bond enthalpy and entropy correction terms. The multicoefficient correlation methods (MCG3/3 and MC-QCISD), with inclusion of specific zero-point scale factors, slightly outperform the other multilevel methods tested (CBS-QB3, G3B3, and G3MP2B3), with significantly less computational cost, and in the case of MC-QCISD, slightly less severe scaling. Four density functional methods, PBE1KCIS, MPW1B95, PBE0, and B1B95 perform nearly as well as the multilevel methods. These results provide an important set of benchmarks relevant to biological phosphoryl transfer reactions.
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Papers by Adam Moser