Dental composite is a material of choice for direct restorations. 1,2 The chemical action of orga... more Dental composite is a material of choice for direct restorations. 1,2 The chemical action of organic solvents associated with lack of good mechanical and physical properties which makes it liable to suffer from dissolution and degradation in the oral cavity. This leads to surface roughness and decreased hardness of the material. 1 Although the initial hardness of the polymerized composite material is sufficient to withstand the masticatory load yet the degradation process that initiates immediately in the oral cavity make the composite material vulnerable to dissolution followed by disintegration. The deterioration of a composite material is an intricate process dependent on the filler quantity, matrix type and the cou
Objective: Erosion of tooth surface is attributed to recent shift in diet pattern and frequent us... more Objective: Erosion of tooth surface is attributed to recent shift in diet pattern and frequent use of beverages. The aim of this research was to evaluate the effects of different beverages on surface topography and hardness of nano-filled composite material. Methods: Sixty flat disc shaped resin composite samples were fabricated and placed in distilled water for 24 hours. After 24 hours test samples were dried and divided into 4 groups. Group A (n=15) specimens were placed in tight amber bottle comprising 25 ml of artificial saliva. Similarly Group B, C and D were stored in equal amounts of orange juice, milk and coca cola drink respectively. Samples were checked for hardness and surface changes were evaluated with scanning electron microscopy. Results: There were strong significant difference observed in samples immersed in orange juice and artificial saliva. A strong significant difference was seen between Group D and Group A. Group A and Group C showed no significant difference. The micro-hardness test showed reduced values among all samples. Conclusion: Beverages consumed daily have a negative influence on hardness and surface degradation of nano-filled dental composite. Comparatively, nano-filled composites possess higher surface area to volume ratio of their fillers particle size may lead to higher surface roughness than other resin based dental biomaterials.
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Photodermatology, Photoimmunology and Photomedicine, Jun 19, 2022
PurposeTo assess the clinical periodontal, bacterial, and immunological outcomes of chloro‐alumin... more PurposeTo assess the clinical periodontal, bacterial, and immunological outcomes of chloro‐aluminum phthalocyanine‐mediated photodynamic therapy (PDT) as an adjunct to dental scaling (DS) versus DS alone among cigarette smokers (CS) and never‐smokers (NS).MethodsA total of 26 patients (13 CS and 13 NS) with clinical and radiographic diagnosis of stage‐II chronic periodontitis were recruited. Each patient from both groups were subjected with two parallel therapies (split‐mouth): PDT + DS (test side) and DS alone (control side). Periodontal parameters were investigated by evaluating plaque scores (PS), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL), and alveolar bone loss (ABL). Subgingival plaque was collected to detect and quantify Porphyromonas gingivalis and Tannerella forsythia using real‐time quantitative polymerase chain reaction (RT‐qPCR) assay. Gingival crevicular fluid was sampled for the quantification of interleukin (IL)‐1β and tumor necrosis factor‐alpha (TNF‐α) using enzyme linked immunosorbent assay. All assessments were performed at baseline, 3 months, and 6 months.ResultsBleeding on probing was significantly reduced at 6 months after PDT + DS in CS groups (p < .05). Mean PD and CAL significantly reduced after both PDT + DS and DS subgroups and among NS and CS groups (p < .05). At 6 months follow‐up, the copy number of both P. gingivalis and T. forsythia remained significantly high in CS group (p < .01). Only PDT + DS subgroup in CS significantly reduced the counts of P. gingivalis and T. forsythia at 3 months and 6 months (p < .05). Only at 6 months did PDT + DS showed statistically significantly reduced IL‐1β levels in the NS group (p < .01). TNF‐α levels significantly reduced in CS group with PDT + DS and DS alone at both 3 months and 6 months follow‐up (p < .01).ConclusionChloro‐aluminum phthalocyanine‐mediated PDT helped to improve the non‐surgical periodontal therapy outcomes among stage‐II chronic periodontitis patients among smokers and never‐smokers.
Journal of Vinyl & Additive Technology, Jan 24, 2022
Resilient denture liners (RDLs) change their hardness in a short time. Hence, their usefulness is... more Resilient denture liners (RDLs) change their hardness in a short time. Hence, their usefulness is limited to the short term only. Therefore, this laboratory study investigated the influence of graphene oxide (GO) nanosheets incorporation on the longevity of a commercially available RDL material. An auto‐polymerizing acrylic‐based RDL was selected for this purpose. The control group (G0) was prepared as such according to the manufacturer's instructions. However, for the G1 group, 0.1 wt/wt% of GO nanosheet was incorporated in powder of RDL. Similarly, G2 group and G3 group were the composites of 0.3 and 0.6 wt/wt% of the GO‐resin matrix. A total of 60 disk‐shaped samples were prepared, having three subgroups with 15 disks each (n = 15). Surface roughness, water contact angle, Shore A hardness, water sorption, and solubility parameters were evaluated using a two‐way analysis of variance (p < .05). GO nanosheets facilitated in reducing the hardness of RDL without affecting the surface roughness and wettability properties. Additionally, statistically reduced water solubility and sorption values were observed in G3 group, that is, 0.69 ± 0.25% and 0.93 ± 0.18%, respectively, compared to 1.17 ± 0.13% and 1.41 ± 0.18%, respectively, of the control group at the end of 14‐day water immersion. The incorporation of GO nanosheets seems a viable option for the enhanced physical properties and clinical life of RDLs.
This laboratory investigation aimed to synthesize and characterize micron-sized Gum Arabic (GA) p... more This laboratory investigation aimed to synthesize and characterize micron-sized Gum Arabic (GA) powder and incorporate it in commercially available GIC luting formulation for enhanced physical and mechanical properties of GIC composite. Oxidation of GA was performed and GA-reinforced GIC in 0.5, 1.0, 2.0, 4.0 & 8.0 wt.% formulations were prepared in disc-shaped using two commercially available GIC luting materials (Medicem and Ketac Cem Radiopaque). While the control groups of both materials were prepared as such. The effect of reinforcement was evaluated in terms of nano hardness, elastic modulus, diametral tensile strength (DTS), compressive strength (CS), water solubility and sorption. Two-way ANOVA and post hoc tests were used to analyze data for statistical significance (p < 0.05). FTIR spectrum confirmed the formation of acid groups in the backbone of polysaccharide chain of GA while XRD peaks confirmed that crystallinity of oxidized GA. The experimental group with 0.5 wt.%...
AIM To assess the efficacy of photosensitizers (CP, riboflavin) and gaseous ozone in comparison t... more AIM To assess the efficacy of photosensitizers (CP, riboflavin) and gaseous ozone in comparison to the conventional radicular dentin disinfectant (NaOCl) on push-out bond strength (PBS) of PFRC post cemented to radicular dentin MATERIAL AND METHOD: Human single-rooted teeth were collected, steriled implanted in polyvinyl pipes up to a cement-o-enamel junction and de coronated. Cleaning and shaping of the canal were performed using the crown down technique followed by obturation of the canal space. Canal space was prepared using peso reamers and samples were divided into four groups based on types of canal disinfectant protocols. Group 1: Riboflavin+ 17%EDTA; group 2: Curcumin Photosensitizer + 17% EDTA; group 3: Gaseous Ozone disinfection (O3) +17% EDTA and group 4 control 2.5% NaOCl +17% EDTA. Within the canal space, fiber post was cemented and cured, and thermocycled. PBS was evaluated using a Universal testing machine (UTM) and failure modes using a stereomicroscope at 40x magnification. One-way analysis of variance (ANOVA) was used to determine the mean and standard deviation of push-out bond strength (PBS). The Tukey multiple comparison tests (p = 0.05) was used to compare the means of PBS RESULTS: The highest PBS was displayed in group 2 CP+ 17% EDTA at all three root levels, coronal (8.81±0.61), middle (7.77±0.55), and apical (5.25±0.61). The lowest PBS was revealed in group 4, disinfected with 2.5% NaOCl +17% EDTA (control) at coronal (6.12±0.54), middle (5.46±0.84), and apical (3.00±1.88) levels. The most prevailed fracture mode was an adhesive failure (cement-dentin interface). CONCLUSION Radicular dentin disinfected with PDT using CP, riboflavin, and O3 displayed similar PBS at all root segments. NaOCl is a convenient, traditional, and commonly used disinfectant, and it's effects on PBS is still controversial.
AIM To assess the push-out bond strength (PBS) of glass fiber post (GFP) conditioned using differ... more AIM To assess the push-out bond strength (PBS) of glass fiber post (GFP) conditioned using different surface treatment regimens bonded to radicular dentin MATERIAL AND METHODS: Sixty central incisors and canine were collected and disinfected. Decoronation following working length was determined using K-file. Rotary file system was used for cleaning and shaping. Canals of all samples were dried with paper points and obturated with gutta percha. Canal space was prepared with peso reamers. Now samples were randomly allocated into six groups based on pretreatment of GFP. Post in group 1 treated with 9% HFA+ Silane, post in group 2 surface treated with silane only, Post in group 3 surface treated with airborne particle (50µm), group 4 post conditioned with photodynamic therapy (PDT), group 5 post pretreatment was performed with MBP and in group 6 GFP was not treated. Conditioned and non-conditioned posts were positioned in canal space and cemented. Each tooth was sectioned coronally, middle and apically. All sections were positioned in universal testing machine (UTM) and debonded surfaces were evaluated for failure modes. The means and standard deviations of PBS were examined using one-way analysis of variance (ANOVA). The means of PBS were compared using Tukey multiple comparison tests with a significance threshold of (p< 0.05). RESULTS Coronal third of group 3 in which posts were sandblasted using airborne Al2O3 particle presented the highest PBS (11.21±0.64 MPa). Whereas, an apical section of group 4 in which posts were treated with PDT exhibited the lowest bond integrity. CONCLUSION Sandblasting using airborne particles (50µm) and hydrogen peroxide (H3PO4) conditioned with GFP exhibited significantly higher bond strength as compared to the control. However, PDT decreases the PBS of fiber post with the root dentin.
BACKGROUND The introduction of modern diagnostic tools has transformed the field of maxillofacial... more BACKGROUND The introduction of modern diagnostic tools has transformed the field of maxillofacial radiology. Odontogenic infection and fascial space involvement have been evaluated with many diagnostic tools, including ultrasonography (USG) and magnetic resonance imaging (MRI). AIM To explore USG as an alternative model to MRI in the detection of fascial space spread of odontogenic infections. METHODS Among 20 patients, 50 fascial spaces were clinically diagnosed with odontogenic infection and included in this prospective study. Fascial space infection involvement was examined by USG and MRI. Results were compared for both and confirmed by microbiological testing. RESULTS Ultrasonography identified 42 (84%) of 50 involved fascial spaces. Whereas MRI identified all 50 (100%). USG could stage the infections from edematous change to cellulitis to complete abscess formation. CONCLUSION MRI was superior in recognizing deep fascial space infections compared to USG. However, USG is a significant addition and has a definite role in prognosticating the stage of infection and exact anatomic location in superficial space infections.
Journal of the mechanical behavior of biomedical materials, Jan 31, 2018
The purpose of this study was to characterize the adhesive interface formed due to the dissolving... more The purpose of this study was to characterize the adhesive interface formed due to the dissolving capability of 4 primer systems into pre-polymerized semi-interpenetrating polymer network (semi-IPN)-based fiber-reinforced composite (FRC) and luting cement. Semi-IPN FRC (everStick C&B, StickTech) prepregs stored for various durations (at 4 °C; 1, 1.5, and 3 years) were used to fabricate the specimens. FRC specimens (n = 10) were light-cured and treated with primers before adhering a luting cement onto them. Each age group was divided into four subgroups according to the primer used: no priming, a dimethacrylate adhesive primer, universal primer, and primer intended for composite surfaces. The degree of monomer conversion (DC%) of the luting cement; nanohardness, elastic modulus and structural information of the luting cement-FRC adhesive interface were measured. According to analysis of variance (P ≤ 0.05), no statistical difference was observed in the DC% among the tested groups. Ho...
Staphylococcus epidermidis is one of most prevalent in dental caries or dental pulp which has the... more Staphylococcus epidermidis is one of most prevalent in dental caries or dental pulp which has the capability of horizontal genetic transfer between different bacterial species in the oropharynx, suggesting that it may evolve with the dissemination of resistant determinants, This study was performed to molecularly characterize and differentiate S. epidermidis isolated from dental caries and healthy individual. Also, two important cytokines in inflammation were assayed caused due to S. epidermidis of health and dental caries sources. Dental caries strains were more resistant with high MIC 50 and MIC 90 value. These isolates also showed the presence of mecA gene and another virulence gene i. e sea and seb comparatively more than healthy individual isolates. SCCmec types, III and IV was more prevalent in dental caries isolates where an as healthy individual was more non-typable. Additionally, the quantity of IL-1β and IL-8 caused due to dental caries isolates was seen more which indicat...
The purpose of this study was to introduce antibacterial property to pits and fissure sealant (PF... more The purpose of this study was to introduce antibacterial property to pits and fissure sealant (PFS) in order to mitigate the major clinical problems associated with PFS, such as microleakage and secondary caries. We prepared a pH reliant cobalt oxide nanoparticle incorporated with minocycline (MNC@CO) and characterized to investigate its antibacterial potential against Streptococcus sobrinus. The physiochemical, morphological, and drug release kinetics at different pH (7.4, 5.0, and 3.5) from nanoparticles were investigated. The MNC@CO were added at 2.5% and 5.0% into experimental PFS and characterized for their antibiofilm capacity, biocompatibility, and mechanical properties including compressive and flexural strength. The groups 2.5% and 5.0% has shown statistically significant antimicrobial capacity against S. sobrinus compared to control (p < .05). The highest percentage of MNC release at different pH (especially at pH 5.0 and 3.5) was observed from 5.0% MNC@CO doped PFS. The PFS doped with 2.5% MNC@CO showed a highest compressive strength (110 MPa) over a period of 70 days as compared to 5.0% MNC@CO (75 MPa) and control (80 MPa). The flexural strength of both experimental groups was lower for both time points (24 h and 30 days) than control. In conclusion, the present study found that 2.5% MNC@CO doped PFS showed considerable anti-biofilm potential without compromising mechanical properties.
Dental composite is a material of choice for direct restorations. 1,2 The chemical action of orga... more Dental composite is a material of choice for direct restorations. 1,2 The chemical action of organic solvents associated with lack of good mechanical and physical properties which makes it liable to suffer from dissolution and degradation in the oral cavity. This leads to surface roughness and decreased hardness of the material. 1 Although the initial hardness of the polymerized composite material is sufficient to withstand the masticatory load yet the degradation process that initiates immediately in the oral cavity make the composite material vulnerable to dissolution followed by disintegration. The deterioration of a composite material is an intricate process dependent on the filler quantity, matrix type and the cou
Objective: Erosion of tooth surface is attributed to recent shift in diet pattern and frequent us... more Objective: Erosion of tooth surface is attributed to recent shift in diet pattern and frequent use of beverages. The aim of this research was to evaluate the effects of different beverages on surface topography and hardness of nano-filled composite material. Methods: Sixty flat disc shaped resin composite samples were fabricated and placed in distilled water for 24 hours. After 24 hours test samples were dried and divided into 4 groups. Group A (n=15) specimens were placed in tight amber bottle comprising 25 ml of artificial saliva. Similarly Group B, C and D were stored in equal amounts of orange juice, milk and coca cola drink respectively. Samples were checked for hardness and surface changes were evaluated with scanning electron microscopy. Results: There were strong significant difference observed in samples immersed in orange juice and artificial saliva. A strong significant difference was seen between Group D and Group A. Group A and Group C showed no significant difference. The micro-hardness test showed reduced values among all samples. Conclusion: Beverages consumed daily have a negative influence on hardness and surface degradation of nano-filled dental composite. Comparatively, nano-filled composites possess higher surface area to volume ratio of their fillers particle size may lead to higher surface roughness than other resin based dental biomaterials.
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Photodermatology, Photoimmunology and Photomedicine, Jun 19, 2022
PurposeTo assess the clinical periodontal, bacterial, and immunological outcomes of chloro‐alumin... more PurposeTo assess the clinical periodontal, bacterial, and immunological outcomes of chloro‐aluminum phthalocyanine‐mediated photodynamic therapy (PDT) as an adjunct to dental scaling (DS) versus DS alone among cigarette smokers (CS) and never‐smokers (NS).MethodsA total of 26 patients (13 CS and 13 NS) with clinical and radiographic diagnosis of stage‐II chronic periodontitis were recruited. Each patient from both groups were subjected with two parallel therapies (split‐mouth): PDT + DS (test side) and DS alone (control side). Periodontal parameters were investigated by evaluating plaque scores (PS), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL), and alveolar bone loss (ABL). Subgingival plaque was collected to detect and quantify Porphyromonas gingivalis and Tannerella forsythia using real‐time quantitative polymerase chain reaction (RT‐qPCR) assay. Gingival crevicular fluid was sampled for the quantification of interleukin (IL)‐1β and tumor necrosis factor‐alpha (TNF‐α) using enzyme linked immunosorbent assay. All assessments were performed at baseline, 3 months, and 6 months.ResultsBleeding on probing was significantly reduced at 6 months after PDT + DS in CS groups (p &lt; .05). Mean PD and CAL significantly reduced after both PDT + DS and DS subgroups and among NS and CS groups (p &lt; .05). At 6 months follow‐up, the copy number of both P. gingivalis and T. forsythia remained significantly high in CS group (p &lt; .01). Only PDT + DS subgroup in CS significantly reduced the counts of P. gingivalis and T. forsythia at 3 months and 6 months (p &lt; .05). Only at 6 months did PDT + DS showed statistically significantly reduced IL‐1β levels in the NS group (p &lt; .01). TNF‐α levels significantly reduced in CS group with PDT + DS and DS alone at both 3 months and 6 months follow‐up (p &lt; .01).ConclusionChloro‐aluminum phthalocyanine‐mediated PDT helped to improve the non‐surgical periodontal therapy outcomes among stage‐II chronic periodontitis patients among smokers and never‐smokers.
Journal of Vinyl & Additive Technology, Jan 24, 2022
Resilient denture liners (RDLs) change their hardness in a short time. Hence, their usefulness is... more Resilient denture liners (RDLs) change their hardness in a short time. Hence, their usefulness is limited to the short term only. Therefore, this laboratory study investigated the influence of graphene oxide (GO) nanosheets incorporation on the longevity of a commercially available RDL material. An auto‐polymerizing acrylic‐based RDL was selected for this purpose. The control group (G0) was prepared as such according to the manufacturer's instructions. However, for the G1 group, 0.1 wt/wt% of GO nanosheet was incorporated in powder of RDL. Similarly, G2 group and G3 group were the composites of 0.3 and 0.6 wt/wt% of the GO‐resin matrix. A total of 60 disk‐shaped samples were prepared, having three subgroups with 15 disks each (n = 15). Surface roughness, water contact angle, Shore A hardness, water sorption, and solubility parameters were evaluated using a two‐way analysis of variance (p &lt; .05). GO nanosheets facilitated in reducing the hardness of RDL without affecting the surface roughness and wettability properties. Additionally, statistically reduced water solubility and sorption values were observed in G3 group, that is, 0.69 ± 0.25% and 0.93 ± 0.18%, respectively, compared to 1.17 ± 0.13% and 1.41 ± 0.18%, respectively, of the control group at the end of 14‐day water immersion. The incorporation of GO nanosheets seems a viable option for the enhanced physical properties and clinical life of RDLs.
This laboratory investigation aimed to synthesize and characterize micron-sized Gum Arabic (GA) p... more This laboratory investigation aimed to synthesize and characterize micron-sized Gum Arabic (GA) powder and incorporate it in commercially available GIC luting formulation for enhanced physical and mechanical properties of GIC composite. Oxidation of GA was performed and GA-reinforced GIC in 0.5, 1.0, 2.0, 4.0 & 8.0 wt.% formulations were prepared in disc-shaped using two commercially available GIC luting materials (Medicem and Ketac Cem Radiopaque). While the control groups of both materials were prepared as such. The effect of reinforcement was evaluated in terms of nano hardness, elastic modulus, diametral tensile strength (DTS), compressive strength (CS), water solubility and sorption. Two-way ANOVA and post hoc tests were used to analyze data for statistical significance (p < 0.05). FTIR spectrum confirmed the formation of acid groups in the backbone of polysaccharide chain of GA while XRD peaks confirmed that crystallinity of oxidized GA. The experimental group with 0.5 wt.%...
AIM To assess the efficacy of photosensitizers (CP, riboflavin) and gaseous ozone in comparison t... more AIM To assess the efficacy of photosensitizers (CP, riboflavin) and gaseous ozone in comparison to the conventional radicular dentin disinfectant (NaOCl) on push-out bond strength (PBS) of PFRC post cemented to radicular dentin MATERIAL AND METHOD: Human single-rooted teeth were collected, steriled implanted in polyvinyl pipes up to a cement-o-enamel junction and de coronated. Cleaning and shaping of the canal were performed using the crown down technique followed by obturation of the canal space. Canal space was prepared using peso reamers and samples were divided into four groups based on types of canal disinfectant protocols. Group 1: Riboflavin+ 17%EDTA; group 2: Curcumin Photosensitizer + 17% EDTA; group 3: Gaseous Ozone disinfection (O3) +17% EDTA and group 4 control 2.5% NaOCl +17% EDTA. Within the canal space, fiber post was cemented and cured, and thermocycled. PBS was evaluated using a Universal testing machine (UTM) and failure modes using a stereomicroscope at 40x magnification. One-way analysis of variance (ANOVA) was used to determine the mean and standard deviation of push-out bond strength (PBS). The Tukey multiple comparison tests (p = 0.05) was used to compare the means of PBS RESULTS: The highest PBS was displayed in group 2 CP+ 17% EDTA at all three root levels, coronal (8.81±0.61), middle (7.77±0.55), and apical (5.25±0.61). The lowest PBS was revealed in group 4, disinfected with 2.5% NaOCl +17% EDTA (control) at coronal (6.12±0.54), middle (5.46±0.84), and apical (3.00±1.88) levels. The most prevailed fracture mode was an adhesive failure (cement-dentin interface). CONCLUSION Radicular dentin disinfected with PDT using CP, riboflavin, and O3 displayed similar PBS at all root segments. NaOCl is a convenient, traditional, and commonly used disinfectant, and it's effects on PBS is still controversial.
AIM To assess the push-out bond strength (PBS) of glass fiber post (GFP) conditioned using differ... more AIM To assess the push-out bond strength (PBS) of glass fiber post (GFP) conditioned using different surface treatment regimens bonded to radicular dentin MATERIAL AND METHODS: Sixty central incisors and canine were collected and disinfected. Decoronation following working length was determined using K-file. Rotary file system was used for cleaning and shaping. Canals of all samples were dried with paper points and obturated with gutta percha. Canal space was prepared with peso reamers. Now samples were randomly allocated into six groups based on pretreatment of GFP. Post in group 1 treated with 9% HFA+ Silane, post in group 2 surface treated with silane only, Post in group 3 surface treated with airborne particle (50µm), group 4 post conditioned with photodynamic therapy (PDT), group 5 post pretreatment was performed with MBP and in group 6 GFP was not treated. Conditioned and non-conditioned posts were positioned in canal space and cemented. Each tooth was sectioned coronally, middle and apically. All sections were positioned in universal testing machine (UTM) and debonded surfaces were evaluated for failure modes. The means and standard deviations of PBS were examined using one-way analysis of variance (ANOVA). The means of PBS were compared using Tukey multiple comparison tests with a significance threshold of (p< 0.05). RESULTS Coronal third of group 3 in which posts were sandblasted using airborne Al2O3 particle presented the highest PBS (11.21±0.64 MPa). Whereas, an apical section of group 4 in which posts were treated with PDT exhibited the lowest bond integrity. CONCLUSION Sandblasting using airborne particles (50µm) and hydrogen peroxide (H3PO4) conditioned with GFP exhibited significantly higher bond strength as compared to the control. However, PDT decreases the PBS of fiber post with the root dentin.
BACKGROUND The introduction of modern diagnostic tools has transformed the field of maxillofacial... more BACKGROUND The introduction of modern diagnostic tools has transformed the field of maxillofacial radiology. Odontogenic infection and fascial space involvement have been evaluated with many diagnostic tools, including ultrasonography (USG) and magnetic resonance imaging (MRI). AIM To explore USG as an alternative model to MRI in the detection of fascial space spread of odontogenic infections. METHODS Among 20 patients, 50 fascial spaces were clinically diagnosed with odontogenic infection and included in this prospective study. Fascial space infection involvement was examined by USG and MRI. Results were compared for both and confirmed by microbiological testing. RESULTS Ultrasonography identified 42 (84%) of 50 involved fascial spaces. Whereas MRI identified all 50 (100%). USG could stage the infections from edematous change to cellulitis to complete abscess formation. CONCLUSION MRI was superior in recognizing deep fascial space infections compared to USG. However, USG is a significant addition and has a definite role in prognosticating the stage of infection and exact anatomic location in superficial space infections.
Journal of the mechanical behavior of biomedical materials, Jan 31, 2018
The purpose of this study was to characterize the adhesive interface formed due to the dissolving... more The purpose of this study was to characterize the adhesive interface formed due to the dissolving capability of 4 primer systems into pre-polymerized semi-interpenetrating polymer network (semi-IPN)-based fiber-reinforced composite (FRC) and luting cement. Semi-IPN FRC (everStick C&B, StickTech) prepregs stored for various durations (at 4 °C; 1, 1.5, and 3 years) were used to fabricate the specimens. FRC specimens (n = 10) were light-cured and treated with primers before adhering a luting cement onto them. Each age group was divided into four subgroups according to the primer used: no priming, a dimethacrylate adhesive primer, universal primer, and primer intended for composite surfaces. The degree of monomer conversion (DC%) of the luting cement; nanohardness, elastic modulus and structural information of the luting cement-FRC adhesive interface were measured. According to analysis of variance (P ≤ 0.05), no statistical difference was observed in the DC% among the tested groups. Ho...
Staphylococcus epidermidis is one of most prevalent in dental caries or dental pulp which has the... more Staphylococcus epidermidis is one of most prevalent in dental caries or dental pulp which has the capability of horizontal genetic transfer between different bacterial species in the oropharynx, suggesting that it may evolve with the dissemination of resistant determinants, This study was performed to molecularly characterize and differentiate S. epidermidis isolated from dental caries and healthy individual. Also, two important cytokines in inflammation were assayed caused due to S. epidermidis of health and dental caries sources. Dental caries strains were more resistant with high MIC 50 and MIC 90 value. These isolates also showed the presence of mecA gene and another virulence gene i. e sea and seb comparatively more than healthy individual isolates. SCCmec types, III and IV was more prevalent in dental caries isolates where an as healthy individual was more non-typable. Additionally, the quantity of IL-1β and IL-8 caused due to dental caries isolates was seen more which indicat...
The purpose of this study was to introduce antibacterial property to pits and fissure sealant (PF... more The purpose of this study was to introduce antibacterial property to pits and fissure sealant (PFS) in order to mitigate the major clinical problems associated with PFS, such as microleakage and secondary caries. We prepared a pH reliant cobalt oxide nanoparticle incorporated with minocycline (MNC@CO) and characterized to investigate its antibacterial potential against Streptococcus sobrinus. The physiochemical, morphological, and drug release kinetics at different pH (7.4, 5.0, and 3.5) from nanoparticles were investigated. The MNC@CO were added at 2.5% and 5.0% into experimental PFS and characterized for their antibiofilm capacity, biocompatibility, and mechanical properties including compressive and flexural strength. The groups 2.5% and 5.0% has shown statistically significant antimicrobial capacity against S. sobrinus compared to control (p < .05). The highest percentage of MNC release at different pH (especially at pH 5.0 and 3.5) was observed from 5.0% MNC@CO doped PFS. The PFS doped with 2.5% MNC@CO showed a highest compressive strength (110 MPa) over a period of 70 days as compared to 5.0% MNC@CO (75 MPa) and control (80 MPa). The flexural strength of both experimental groups was lower for both time points (24 h and 30 days) than control. In conclusion, the present study found that 2.5% MNC@CO doped PFS showed considerable anti-biofilm potential without compromising mechanical properties.
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