Amiy Chaturvedi

Medical informatics has recently been a part of bioinformatics, the clinical proteomic plays an important role in the analysis of genetic. Proteomic is set to play a major role in defining biological systems at a molecular level. Medicinal plants are used as a raw material for some important drugs and antibiotics brought about a revolution in controlling different disease. The potential of higher plants as source for new drugs is still largely unexplored. Proteomic provides essential mechanisms to analyze information generated from using databases techniques. In particular, these approaches have made possible for the identification of genes and pathways involved in synthesis of bioactive metabolites in medicinal plants. Here we look at large scale proteomic in the post genomic era and reflect on its future impact to study biological systems in health science and medical research. Its main aim is to convert raw gene sequences data and measurement of gene expression, to informations describing the actions of those proteins controlling biological systems. This paper reviews on the bioinformatics have deal with to medicinal plants research and highlight a crucial role in working towards health science.

Commercial household detergents are diverse group of chemical that is best known for their wide used in laundry industries and household cleaning product. After use, residuals (Surfactant) detergents are discharge into sewage system directly or indirectly into the surface water and most of them end up dispersed into the different environment compartment of soil and water.”Water is facing lots of problems due to domestic waste. These toxic effects of surfactant damaging biodiversity of aquatic environment. Most of aquatic microorganism develops a bio-mechanism for degradation of harmful heavy metals discharge in water at high level. As we know that aquatic environment specially water “fungi” have excellent potential for metal accumulation, particularly genera of Rhizopus, Aspergillus, Streptoverticillum, Sacchromyctes. In general most of commercial household (Surfactants) detergents are biodegradable and amount of it can be commerciallyreduced by secondary treatment of Municipal sewa...

In this review report we like to focus on the new challenges in methodology of modern biology be used in medical science. Today human health is a primary issue to cure disease, undoubtedly the answer to this is bioinformatics or (In-silco) tools has change the concept of treating patients to understand the need of genomic medicine in use. Those with new modes of action in clinical treatment, is a major health concern in medical science. On global prospective scientific role in constructing new ideas to remediate health care to treat disease exciting in nature is challenging task. So awareness needs to accelerate store clinical datasets for scientific represents to design genomic drugs. This new outline will drive the medical to discover public data and create a cognitive approach to use technology cheaper at cost effective mode. Key word: Bioinformatics (In-silco), clinical datasets, genomic medicine, cognitive

Water is the most important and vital molecule of our planet and covers 75 % of earth surface. But it is getting polluted due to high industrial growth. The heavy metals produced by industrial activities are recurrently added to it and considered as dangerous pollutants. Increasing concentration of toxic heavy metals (Pb(2+), Cd(2+), Hg(2+), Ni(2+)) in water is a severe threat for human. Heavy metal contaminated water is highly carcinogenic and poisonous at even relatively low concentrations. When they discharged in water bodies, they dissolve in the water and are distributed in the food chain. Bacteria and fungi are efficient microbes that frequently transform heavy metals and remove toxicity. The application of bacteria and fungi may offer cost benefit in water treatment plants for heavy metal transformation and directly related to public health and environmental safety issues. The heavy metals transformation rate in water is also dependent on the enzymatic capability of microorganisms. By transforming toxic heavy metals microbes sustain aquatic and terrestrial life. Therefore the application of microbiological biomass for heavy metal transformation and removal from aquatic ecosystem is highly significant and striking. This paper reviews the microbial transformation of heavy metal, microbe metal interaction and different approaches for microbial heavy metal remediation from water bodies.

In our previous work, we reported magnetic domain structures of CoFeB/MgO and their electric-field modulation [1]. In this work, we investigate the CoFeB thickness tCoFeB dependence of domain structures and determine the CoFeB thickness dependence of exchange stiffness constants AS. Stacks, Ta (2 nm)/ Co40Fe40B20 (tCoFeB = 1.18 – 1.30 nm)/ MgO (5 nm)/ Al2O3 (5 nm), are deposited by dc/rf magnetron sputtering on a thermally oxidized Si substrate. The samples are annealed at 350 o C for 1 hour under a perpendicular magnetic field of 0.4 T in vacuum (10 -6 Torr). The tCoFeB is determined from the deposition rate of CoFeB. The samples are demagnetized by applying an ac perpendicular magnetic field with exponentially decaying amplitude. The domain structures at demagnetized state are observed by magneto-optical polar-Kerr-effect microscope. Figure 1(a) shows a typical domain structure observed for the film with tCoFeB = 1.18 nm. Clear maze pattern is observed for the films with 1.18 nm ...