Importance: Spinal disorders are common and associated with high rates of low value care. Efforts... more Importance: Spinal disorders are common and associated with high rates of low value care. Efforts to improve guideline concordance and value benefit from understanding the influence of population and environmental factors. Objective: Quantify geographic variation in population race/ethnicity, socioeconomic status, and health care professional (HCP) availability, and associated variation in service utilization and total cost for management of spinal disorders. Design, Setting, and Participants: This retrospective cohort study examines a national sample of 1,534,280 complete episodes of a spinal disorder experienced in 2017-2019 using zip code and episode of care. Risk ratio (RR) and 95% confidence interval (CI), and ridge regression were used to examine associations between independent and dependent measures. Exposures: Zip code level measures of population race/ethnicity and socioeconomic status were the primary independent measures. Main Outcomes and Measures: Availability of and a...
Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential w... more Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential were studied in patients with primary degenerative dementia during a double-blind, placebo-controlled study of ergoloid mesylates (Hy-dergine). After 18 weeks of treatment, P300 latency and amplitude, recorded at three scalp electrode sites, had not changed significantly. Smooth pursuit gain was elevated for the drug group under some stimulus conditions, suggesting a normalization of pursuit eye movement functioning. However, the results of several other measures of the quality of pursuit eye movements failed to corroborate this finding. (J Geriatr Psychiatry Neurol 1990; 3:41-47). rgoloid mesylates (Hydergine) has been in use for over 30 years in the treatment of pri-mary degenerative dementia (I’DD). Although it was initially thought to be a vasodilator, there is little ex-perimental evidence that it increases total or regional blood flow. Hydergine has been found to bind in vitro to do...
Focus groups were conducted to explore health-related beliefs and experiences of African American... more Focus groups were conducted to explore health-related beliefs and experiences of African American, Hispanic/ Latino, American Indian, and Hmong people with dia-betes and engage community members in improving diabetes care and education for these populations. Eighty participants attended 12 focus groups, 3 per pop-ulation. Major themes were loss of health attributed to modern American lifestyles, lack of confidence in the medical system, and the importance of spirituality. Par-ticipants recommended improvements in the areas of health care, diabetes education, social support, and community action. Their recommendations emphasize the importance of respectful, knowledgeable health care providers; culturally responsive diabetes educa-tion for people with diabetes and their families; and broad-based community action. These recommenda-tions align with current public health priorities and medical knowledge. It is proposed that healthy tradi-tions from diverse populations can be leveraged to...
Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate... more Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate dementia of the Alzheimer type (DAT) and 16 age-matched normal controls. There were no significant differences between the two groups on any latency measure (wave V latency, I-V and III-V interpeak latencies). Within the DAT group, there was no association between BAEP latency measures and cognitive status, indexed by scores on the Mini-Mental Status Exam (MMSE). Eight of the DAT subjects were retested 6 months and one year later. Despite significant evidence of continued cognitive decline, there were no changes in BAEP latency measures over time. Furthermore, BAEP latency measures at initial testing did not predict the degree of cognitive decline over the one year time interval. The results show that BAEP latency is unaffected in patients with mild-to-moderate DAT.
Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate... more Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate dementia of the Alzheimer type (DAT) and 16 age-matched normal controls. There were no significant differences between the two groups on any latency measure (wave V latency, I-V and III-V interpeak latencies). Within the DAT group, there was no association between BAEP latency measures and cognitive status, indexed by scores on the Mini-Mental Status Exam (MMSE). Eight of the DAT subjects were retested 6 months and one year later. Despite significant evidence of continued cognitive decline, there were no changes in BAEP latency measures over time. Furthermore, BAEP latency measures at initial testing did not predict the degree of cognitive decline over the one year time interval. The results show that BAEP latency is unaffected in patients with mild-to-moderate DAT.
Journal of Geriatric Psychiatry and Neurology, 1990
Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential w... more Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential were studied in patients with primary degenerative dementia during a double-blind, placebo-controlled study of ergoloid mesylates (Hydergine). After 18 weeks of treatment, P300 latency and amplitude, recorded at three scalp electrode sites, had not changed significantly. Smooth pursuit gain was elevated for the drug group under some stimulus conditions, suggesting a normalization of pursuit eye movement functioning. However, the results of several other measures of the quality of pursuit eye movements failed to corroborate this finding. ( J Geriatr Psychiatry Neurol 1990; 3:41-47).
Focus groups were conducted to explore health-related beliefs and experiences of African American... more Focus groups were conducted to explore health-related beliefs and experiences of African American, Hispanic/Latino, American Indian, and Hmong people with diabetes and engage community members in improving diabetes care and education for these populations. Eighty participants attended 12 focus groups, 3 per population. Major themes were loss of health attributed to modern American lifestyles, lack of confidence in the medical system, and the importance of spirituality. Participants recommended improvements in the areas of health care, diabetes education, social support, and community action. Their recommendations emphasize the importance of respectful, knowledgeable health care providers; culturally responsive diabetes education for people with diabetes and their families; and broad-based community action. These recommendations align with current public health priorities and medical knowledge. It is proposed that healthy traditions from diverse populations can be leveraged to improv...
Importance: Spinal disorders are common and associated with high rates of low value care. Efforts... more Importance: Spinal disorders are common and associated with high rates of low value care. Efforts to improve guideline concordance and value benefit from understanding the influence of population and environmental factors. Objective: Quantify geographic variation in population race/ethnicity, socioeconomic status, and health care professional (HCP) availability, and associated variation in service utilization and total cost for management of spinal disorders. Design, Setting, and Participants: This retrospective cohort study examines a national sample of 1,534,280 complete episodes of a spinal disorder experienced in 2017-2019 using zip code and episode of care. Risk ratio (RR) and 95% confidence interval (CI), and ridge regression were used to examine associations between independent and dependent measures. Exposures: Zip code level measures of population race/ethnicity and socioeconomic status were the primary independent measures. Main Outcomes and Measures: Availability of and a...
Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential w... more Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential were studied in patients with primary degenerative dementia during a double-blind, placebo-controlled study of ergoloid mesylates (Hy-dergine). After 18 weeks of treatment, P300 latency and amplitude, recorded at three scalp electrode sites, had not changed significantly. Smooth pursuit gain was elevated for the drug group under some stimulus conditions, suggesting a normalization of pursuit eye movement functioning. However, the results of several other measures of the quality of pursuit eye movements failed to corroborate this finding. (J Geriatr Psychiatry Neurol 1990; 3:41-47). rgoloid mesylates (Hydergine) has been in use for over 30 years in the treatment of pri-mary degenerative dementia (I’DD). Although it was initially thought to be a vasodilator, there is little ex-perimental evidence that it increases total or regional blood flow. Hydergine has been found to bind in vitro to do...
Focus groups were conducted to explore health-related beliefs and experiences of African American... more Focus groups were conducted to explore health-related beliefs and experiences of African American, Hispanic/ Latino, American Indian, and Hmong people with dia-betes and engage community members in improving diabetes care and education for these populations. Eighty participants attended 12 focus groups, 3 per pop-ulation. Major themes were loss of health attributed to modern American lifestyles, lack of confidence in the medical system, and the importance of spirituality. Par-ticipants recommended improvements in the areas of health care, diabetes education, social support, and community action. Their recommendations emphasize the importance of respectful, knowledgeable health care providers; culturally responsive diabetes educa-tion for people with diabetes and their families; and broad-based community action. These recommenda-tions align with current public health priorities and medical knowledge. It is proposed that healthy tradi-tions from diverse populations can be leveraged to...
Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate... more Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate dementia of the Alzheimer type (DAT) and 16 age-matched normal controls. There were no significant differences between the two groups on any latency measure (wave V latency, I-V and III-V interpeak latencies). Within the DAT group, there was no association between BAEP latency measures and cognitive status, indexed by scores on the Mini-Mental Status Exam (MMSE). Eight of the DAT subjects were retested 6 months and one year later. Despite significant evidence of continued cognitive decline, there were no changes in BAEP latency measures over time. Furthermore, BAEP latency measures at initial testing did not predict the degree of cognitive decline over the one year time interval. The results show that BAEP latency is unaffected in patients with mild-to-moderate DAT.
Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate... more Brainstem auditory evoked potentials (BAEPs) were recorded from 33 patients with mild-to-moderate dementia of the Alzheimer type (DAT) and 16 age-matched normal controls. There were no significant differences between the two groups on any latency measure (wave V latency, I-V and III-V interpeak latencies). Within the DAT group, there was no association between BAEP latency measures and cognitive status, indexed by scores on the Mini-Mental Status Exam (MMSE). Eight of the DAT subjects were retested 6 months and one year later. Despite significant evidence of continued cognitive decline, there were no changes in BAEP latency measures over time. Furthermore, BAEP latency measures at initial testing did not predict the degree of cognitive decline over the one year time interval. The results show that BAEP latency is unaffected in patients with mild-to-moderate DAT.
Journal of Geriatric Psychiatry and Neurology, 1990
Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential w... more Changes in smooth pursuit eye movements and the P300 component of the auditory evoked potential were studied in patients with primary degenerative dementia during a double-blind, placebo-controlled study of ergoloid mesylates (Hydergine). After 18 weeks of treatment, P300 latency and amplitude, recorded at three scalp electrode sites, had not changed significantly. Smooth pursuit gain was elevated for the drug group under some stimulus conditions, suggesting a normalization of pursuit eye movement functioning. However, the results of several other measures of the quality of pursuit eye movements failed to corroborate this finding. ( J Geriatr Psychiatry Neurol 1990; 3:41-47).
Focus groups were conducted to explore health-related beliefs and experiences of African American... more Focus groups were conducted to explore health-related beliefs and experiences of African American, Hispanic/Latino, American Indian, and Hmong people with diabetes and engage community members in improving diabetes care and education for these populations. Eighty participants attended 12 focus groups, 3 per population. Major themes were loss of health attributed to modern American lifestyles, lack of confidence in the medical system, and the importance of spirituality. Participants recommended improvements in the areas of health care, diabetes education, social support, and community action. Their recommendations emphasize the importance of respectful, knowledgeable health care providers; culturally responsive diabetes education for people with diabetes and their families; and broad-based community action. These recommendations align with current public health priorities and medical knowledge. It is proposed that healthy traditions from diverse populations can be leveraged to improv...
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