In Ethiopia, Calpurnia aurea (digita), a traditional medicinal plant is used for the treatment of... more In Ethiopia, Calpurnia aurea (digita), a traditional medicinal plant is used for the treatment of syphilis, malaria, rabies, diabetes, hypertension, diarrhoea, leishmaniasis, trachoma, elephantiasis, fungal diseases and different other ailment of human and animals. It is important to find a scientific evidence for the traditional use and standardization of the medicinal plant to ensure safety, efficacy and quality through preliminary phytochemical screening, analysis, safety and efficacy studies. Based on this review, scientific studies conducted on Calpurnia aurea-a traditional medicinal plant found in Ethiopia-revealed that the leaves, bark, seed and root of the plant have potential medicinal values for various diseases and validate its traditional uses. Further studies of detailed phytochemical screening, further isolations and characterizations of each active ingredients is required to identify the exact chemical compound (s) responsible for the activities observed from the present studies for development of potential new drugs and applications in pharmaceutical industry. It is also important to conduct clinical trial in human subject to incorporate the medicinal plant to modern healthcare system and for standardization.
The demand for herbal medicine is increasing as herbs are less toxic, affordable, and culturally ... more The demand for herbal medicine is increasing as herbs are less toxic, affordable, and culturally acceptable than the conventional drugs in developing countries. Thus, the increase in demand for standardization to ensure safety, purity and quality of medicinal plant. Standardization is a process of confirming herbal medicine identity and determination of its quality and purity. It involves botanical, physical, chemical and biological evaluations. These require application of different analytical methods and tools for standardization and phytochemical investigation of medicinal plants. The aim of this review is to explore analytical methods used for standardization of medicinal plants. A comprehensive web based literature review is employed in order to retrieve relevant information using international scientific databases including PubMed, Science direct, Web of Science, Google scholar. The review of selected 34 original published research articles were evaluated and summarized. The result this review showed that several analytical methods are employed and developed for standardization including chromatographic, TLC, GC, HPTLC and HPLC fingerprints, spectroscopic; UV, Fluorescence, MS, FT-IR, AAS and NMR are commonly applied techniques for different analytical purposes which are mainly used in physicochemical and phytochemical characterization of medicinal plants. Gel electrophoresis and DNA fingerprint are also applicable for botanical identification. The choice of analytical methods may depend on phytochemical, physicochemical nature of medicinal plant, selectivity and accuracy of analytical method. Development of selective analytical method is recommended for pesticide and Alfa toxin analysis to further ensure safety, quality and for complete standardization of medicinal plants.
In Ethiopia, Calpurnia aurea (digita), a traditional medicinal plant is used for the treatment of... more In Ethiopia, Calpurnia aurea (digita), a traditional medicinal plant is used for the treatment of syphilis, malaria, rabies, diabetes, hypertension, diarrhoea, leishmaniasis, trachoma, elephantiasis, fungal diseases and different other ailment of human and animals. It is important to find a scientific evidence for the traditional use and standardization of the medicinal plant to ensure safety, efficacy and quality through preliminary phytochemical screening, analysis, safety and efficacy studies. Based on this review, scientific studies conducted on Calpurnia aurea-a traditional medicinal plant found in Ethiopia-revealed that the leaves, bark, seed and root of the plant have potential medicinal values for various diseases and validate its traditional uses. Further studies of detailed phytochemical screening, further isolations and characterizations of each active ingredients is required to identify the exact chemical compound (s) responsible for the activities observed from the present studies for development of potential new drugs and applications in pharmaceutical industry. It is also important to conduct clinical trial in human subject to incorporate the medicinal plant to modern healthcare system and for standardization.
The demand for herbal medicine is increasing as herbs are less toxic, affordable, and culturally ... more The demand for herbal medicine is increasing as herbs are less toxic, affordable, and culturally acceptable than the conventional drugs in developing countries. Thus, the increase in demand for standardization to ensure safety, purity and quality of medicinal plant. Standardization is a process of confirming herbal medicine identity and determination of its quality and purity. It involves botanical, physical, chemical and biological evaluations. These require application of different analytical methods and tools for standardization and phytochemical investigation of medicinal plants. The aim of this review is to explore analytical methods used for standardization of medicinal plants. A comprehensive web based literature review is employed in order to retrieve relevant information using international scientific databases including PubMed, Science direct, Web of Science, Google scholar. The review of selected 34 original published research articles were evaluated and summarized. The result this review showed that several analytical methods are employed and developed for standardization including chromatographic, TLC, GC, HPTLC and HPLC fingerprints, spectroscopic; UV, Fluorescence, MS, FT-IR, AAS and NMR are commonly applied techniques for different analytical purposes which are mainly used in physicochemical and phytochemical characterization of medicinal plants. Gel electrophoresis and DNA fingerprint are also applicable for botanical identification. The choice of analytical methods may depend on phytochemical, physicochemical nature of medicinal plant, selectivity and accuracy of analytical method. Development of selective analytical method is recommended for pesticide and Alfa toxin analysis to further ensure safety, quality and for complete standardization of medicinal plants.
Uploads
Papers by Baresa Ayana