Sesamum indicum is considered an underutilized oil-bearing seed in the semi-arid regions of Ghana... more Sesamum indicum is considered an underutilized oil-bearing seed in the semi-arid regions of Ghana. Nonetheless, it is a promising source of food with both nutritional and therapeutic benefits. The aim of the present study was to evaluate the antioxidant properties S. indicum seeds using different extraction solvents. The seeds were obtained from the local farmers and prepared for analysis. The bioactive compounds present in the seeds were extracted using hexane, ethyl acetate, ethanol and water and their yields quantified. Total phenolic content (TPC), Condensed tannin content (TTC) and Total antioxidant capacity (TAC) , and DPPH radical scaveging assay were analyzed using standard methods. Antinutrients such as saponins, alkaloids, phytates and oxalates were also analyzed from the powdered seeds. Two chemometric methods; hierarchical cluster analysis (HCA) and Pearson correlation were employed to evaluate the interdependence of the various parameters to result in their antioxidant ...
International Journal of Chemical and Biochemical Sciences, 2021
The study focused on using locally produced palm kernel oil, palm ethanol and CaO catalyst from g... more The study focused on using locally produced palm kernel oil, palm ethanol and CaO catalyst from guinea fowl eggshells for biodiesel production. The physicochemical properties such as density (0.8936±0.00008165 g/ml), viscosity (83.32±0.193cP/P), refractive index (1.4540±0.00036), pH (5.89±0.084 mol/L H +), acid value (13.9±0.3 mgKOH/g), saponification value (283.305±23.24 mgKOH/g) and iodine value (20.7±5.77 mgI 2 /g) of the crude oil was determined. The transesterification process was carried out by optimizing reaction conditions using the One-Factor (OFAC) at a time method. The biodiesel produced from optimum conditions had density (0.877±0.001g/ml), iodine value (13.97±1.037 mgI 2 /g) and cetane index (76.215±0.531). The results also gave a kinematic viscosity (7.87±0.531 mm²/s), pour point (8.667±0.943°C), acid value (0.92±0.145 mgKOH/g) and saponification value (161.75±11.017 mgKOH/g).
Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a... more Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a wide range of diseases in West Africa. This study aimed at assessing the antioxidant and antimicrobial activities of extracts of the stem bark of F. africana and F. elastica. The dried, milled stem barks of F. africana and F. elastica were extracted with water and 70% ethanol by cold maceration. Total antioxidant capacity (TAC), total phenolic content (TPC), total flavonoids, and tannins were determined using standard methods. The extracts were tested against bacterial and fungal pathogens, namely; Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Candida albicans. The zone of inhibition, minimum inhibitory concentration (MIC), activity index, and the total antimicrobial activity of the extracts on the organisms were evaluated. Preliminary phytochemical screening revealed the presence of flavonoids, reducing sugars, anthocyanins, t...
Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a... more Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a wide range of diseases in West Africa. This study aimed at assessing the antioxidant and antimicrobial activities of extracts of the stem bark of F. africana and F. elastica. The dried, milled stem barks of F. africana and F. elastica were extracted with water and 70% ethanol by cold maceration. Total antioxidant capacity (TAC), total phenolic content (TPC), total flavonoids, and tannins were determined using standard methods. The extracts were tested against bacterial and fungal pathogens, namely; Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Candida albicans. The zone of inhibition, minimum inhibitory concentration (MIC), activity index, and the total antimicrobial activity of the extracts on the organisms were evaluated. Preliminary phytochemical screening revealed the presence of flavonoids, reducing sugars, anthocyanins, t...
This study sought to explore the medicinal properties of extracts obtained from C. edulis seeds. ... more This study sought to explore the medicinal properties of extracts obtained from C. edulis seeds. The seeds were obtained from farms in the Upper East Region of Ghana, dried and milled into coarse powder. Petroleum ether, ethyl acetate and methanol were used to extract the bioactive compounds present in the seeds by the cold maceration method. Antioxidant properties of the extracts were evaluated using the Phosphomolybdenum and DPPH free radical scavenging assays. The Folin-Ciocalteu assay was used to estimate the total phenol content and carrageenan-induced paw oedema model in chicks employed for the anti-inflammatory effects. The results showed that methanol extract had the highest antioxidant and anti-inflammatory activities while the petroleum ether extract showed the least activity. The anti-inflammatory activity of the methanol extract (31.3% oedema inhibition at 300 mg/kg body weight) was however lower than diclofenac (54.04% oedema inhibition at 100 mg/kg body weight), the re...
Sesamum indicum is considered an underutilized oil-bearing seed in the semi-arid regions of Ghana... more Sesamum indicum is considered an underutilized oil-bearing seed in the semi-arid regions of Ghana. Nonetheless, it is a promising source of food with both nutritional and therapeutic benefits. The aim of the present study was to evaluate the antioxidant properties S. indicum seeds using different extraction solvents. The seeds were obtained from the local farmers and prepared for analysis. The bioactive compounds present in the seeds were extracted using hexane, ethyl acetate, ethanol and water and their yields quantified. Total phenolic content (TPC), Condensed tannin content (TTC) and Total antioxidant capacity (TAC) , and DPPH radical scaveging assay were analyzed using standard methods. Antinutrients such as saponins, alkaloids, phytates and oxalates were also analyzed from the powdered seeds. Two chemometric methods; hierarchical cluster analysis (HCA) and Pearson correlation were employed to evaluate the interdependence of the various parameters to result in their antioxidant ...
International Journal of Chemical and Biochemical Sciences, 2021
The study focused on using locally produced palm kernel oil, palm ethanol and CaO catalyst from g... more The study focused on using locally produced palm kernel oil, palm ethanol and CaO catalyst from guinea fowl eggshells for biodiesel production. The physicochemical properties such as density (0.8936±0.00008165 g/ml), viscosity (83.32±0.193cP/P), refractive index (1.4540±0.00036), pH (5.89±0.084 mol/L H +), acid value (13.9±0.3 mgKOH/g), saponification value (283.305±23.24 mgKOH/g) and iodine value (20.7±5.77 mgI 2 /g) of the crude oil was determined. The transesterification process was carried out by optimizing reaction conditions using the One-Factor (OFAC) at a time method. The biodiesel produced from optimum conditions had density (0.877±0.001g/ml), iodine value (13.97±1.037 mgI 2 /g) and cetane index (76.215±0.531). The results also gave a kinematic viscosity (7.87±0.531 mm²/s), pour point (8.667±0.943°C), acid value (0.92±0.145 mgKOH/g) and saponification value (161.75±11.017 mgKOH/g).
Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a... more Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a wide range of diseases in West Africa. This study aimed at assessing the antioxidant and antimicrobial activities of extracts of the stem bark of F. africana and F. elastica. The dried, milled stem barks of F. africana and F. elastica were extracted with water and 70% ethanol by cold maceration. Total antioxidant capacity (TAC), total phenolic content (TPC), total flavonoids, and tannins were determined using standard methods. The extracts were tested against bacterial and fungal pathogens, namely; Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Candida albicans. The zone of inhibition, minimum inhibitory concentration (MIC), activity index, and the total antimicrobial activity of the extracts on the organisms were evaluated. Preliminary phytochemical screening revealed the presence of flavonoids, reducing sugars, anthocyanins, t...
Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a... more Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a wide range of diseases in West Africa. This study aimed at assessing the antioxidant and antimicrobial activities of extracts of the stem bark of F. africana and F. elastica. The dried, milled stem barks of F. africana and F. elastica were extracted with water and 70% ethanol by cold maceration. Total antioxidant capacity (TAC), total phenolic content (TPC), total flavonoids, and tannins were determined using standard methods. The extracts were tested against bacterial and fungal pathogens, namely; Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Candida albicans. The zone of inhibition, minimum inhibitory concentration (MIC), activity index, and the total antimicrobial activity of the extracts on the organisms were evaluated. Preliminary phytochemical screening revealed the presence of flavonoids, reducing sugars, anthocyanins, t...
This study sought to explore the medicinal properties of extracts obtained from C. edulis seeds. ... more This study sought to explore the medicinal properties of extracts obtained from C. edulis seeds. The seeds were obtained from farms in the Upper East Region of Ghana, dried and milled into coarse powder. Petroleum ether, ethyl acetate and methanol were used to extract the bioactive compounds present in the seeds by the cold maceration method. Antioxidant properties of the extracts were evaluated using the Phosphomolybdenum and DPPH free radical scavenging assays. The Folin-Ciocalteu assay was used to estimate the total phenol content and carrageenan-induced paw oedema model in chicks employed for the anti-inflammatory effects. The results showed that methanol extract had the highest antioxidant and anti-inflammatory activities while the petroleum ether extract showed the least activity. The anti-inflammatory activity of the methanol extract (31.3% oedema inhibition at 300 mg/kg body weight) was however lower than diclofenac (54.04% oedema inhibition at 100 mg/kg body weight), the re...
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