A quasi-adiabatic calorimeter is described by which the principal electron beam parameters, viz. ... more A quasi-adiabatic calorimeter is described by which the principal electron beam parameters, viz. electron energy, beam current and (separately) beam power, were determined. The nominal beam power at which these measurements were made was 3 kW (2 mA and 1500 kV). The electron energy was also determined from their range in polyethylene by using the same calorimeter as detector. Considerably lower values than nominal were found both for current (1.56 mA instead of 2. mA) and for energy (1260 keV instead of 1500 keV), which brought down the beam power by one third. The reliability and confidence of results was cross-checked and a good mutual agreement was found.
Modified combustion procedure, named as polymer complex solution method (PCS), was used for synth... more Modified combustion procedure, named as polymer complex solution method (PCS), was used for synthesis of CeO 2 nanopowder. As fuel was employed polyethylene glycol (PEG) with average molecular weight 200. Post-synthesis thermal treatments were done at 800°C for 2 hours. X-ray powder diffraction, electron microscopy (SEM and TEM), laser light scattering, infrared spectroscopy, UV-VIS diffuse reflectance spectroscopy and luminescence spectroscopy were used as characterization methods. The objectives were to investigate the structure and morphology of the synthesized powder, in particular the aggregation and particle size distribution, and its luminescence properties. Photoluminescent properties of CeO 2 nanopowder were determined from its emission and excitation spectra. In the excitation spectra two lines were present: one at 322 nm and other at 356 nm. Two lines were also visible in the emission spectra, one at 427 nm and other at 492 nm. Violet emission placed at 427 nm and excitat...
Glucocorticoids, essential for normal hypothalamic-pituitary-adrenal (HPA) axis activity, exert t... more Glucocorticoids, essential for normal hypothalamic-pituitary-adrenal (HPA) axis activity, exert their action on the hippocampus through two types of corticosteroid receptors: the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR). Recent studies report that exposure of juvenile rats to cranial irradiation adversely affects HPA axis stability leading to its activation along with radiation- induced inflammation. This study was aimed to examine the acute effects of radiation on HPA axis activity and hippocampal corticosteroid receptor expression in 18-day-old rats. Since immobilization was part of irradiation procedure, both irradiated and sham-irradiated animals were exposed to this unavoidable stress. Our results demonstrate that the irradiated rats exhibited different pattern of corticosteroid receptor expression and hormone levels compared to respective controls. These differences included upregulation of GR protein in the hippocampus with a concomitant elevation ...
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2008
The choice of the spin-trap that is to be applied in any EPR study represents the crossroad betwe... more The choice of the spin-trap that is to be applied in any EPR study represents the crossroad between a comprehensive investigation and an "ordinary" quantification of production of radicals. So, the scope of our study was to compare the performance of different spin-traps for qualitative analysis of radical-generating systems, and their ability to recognize previously unnoticed radicals. In addition, we present a brief account of the difficulties involved in the detection of oxygen-centered radicals in chemical and biological systems accompanied by the rationale for using the EPR spin-trapping technique in quantitative studies of such reactive species. Certain technical aspects of EPR experiments related to efficient trapping of free radicals in biochemical systems are also discussed. As an example we present here results obtained using EPR spectroscopy and the spin-trap DEPMPO, which show that the Fenton reaction, as well as various biological systems generate a previously unappreciated hydrogen (*H) atom.
A quasi-adiabatic calorimeter is described by which the principal electron beam parameters, viz. ... more A quasi-adiabatic calorimeter is described by which the principal electron beam parameters, viz. electron energy, beam current and (separately) beam power, were determined. The nominal beam power at which these measurements were made was 3 kW (2 mA and 1500 kV). The electron energy was also determined from their range in polyethylene by using the same calorimeter as detector. Considerably lower values than nominal were found both for current (1.56 mA instead of 2. mA) and for energy (1260 keV instead of 1500 keV), which brought down the beam power by one third. The reliability and confidence of results was cross-checked and a good mutual agreement was found.
Modified combustion procedure, named as polymer complex solution method (PCS), was used for synth... more Modified combustion procedure, named as polymer complex solution method (PCS), was used for synthesis of CeO 2 nanopowder. As fuel was employed polyethylene glycol (PEG) with average molecular weight 200. Post-synthesis thermal treatments were done at 800°C for 2 hours. X-ray powder diffraction, electron microscopy (SEM and TEM), laser light scattering, infrared spectroscopy, UV-VIS diffuse reflectance spectroscopy and luminescence spectroscopy were used as characterization methods. The objectives were to investigate the structure and morphology of the synthesized powder, in particular the aggregation and particle size distribution, and its luminescence properties. Photoluminescent properties of CeO 2 nanopowder were determined from its emission and excitation spectra. In the excitation spectra two lines were present: one at 322 nm and other at 356 nm. Two lines were also visible in the emission spectra, one at 427 nm and other at 492 nm. Violet emission placed at 427 nm and excitat...
Glucocorticoids, essential for normal hypothalamic-pituitary-adrenal (HPA) axis activity, exert t... more Glucocorticoids, essential for normal hypothalamic-pituitary-adrenal (HPA) axis activity, exert their action on the hippocampus through two types of corticosteroid receptors: the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR). Recent studies report that exposure of juvenile rats to cranial irradiation adversely affects HPA axis stability leading to its activation along with radiation- induced inflammation. This study was aimed to examine the acute effects of radiation on HPA axis activity and hippocampal corticosteroid receptor expression in 18-day-old rats. Since immobilization was part of irradiation procedure, both irradiated and sham-irradiated animals were exposed to this unavoidable stress. Our results demonstrate that the irradiated rats exhibited different pattern of corticosteroid receptor expression and hormone levels compared to respective controls. These differences included upregulation of GR protein in the hippocampus with a concomitant elevation ...
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2008
The choice of the spin-trap that is to be applied in any EPR study represents the crossroad betwe... more The choice of the spin-trap that is to be applied in any EPR study represents the crossroad between a comprehensive investigation and an "ordinary" quantification of production of radicals. So, the scope of our study was to compare the performance of different spin-traps for qualitative analysis of radical-generating systems, and their ability to recognize previously unnoticed radicals. In addition, we present a brief account of the difficulties involved in the detection of oxygen-centered radicals in chemical and biological systems accompanied by the rationale for using the EPR spin-trapping technique in quantitative studies of such reactive species. Certain technical aspects of EPR experiments related to efficient trapping of free radicals in biochemical systems are also discussed. As an example we present here results obtained using EPR spectroscopy and the spin-trap DEPMPO, which show that the Fenton reaction, as well as various biological systems generate a previously unappreciated hydrogen (*H) atom.
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Papers by Bojana Lj. Secerov