Open Access by Domenico Bonamonte
Nickel is the major cause of allergic contact dermatitis. It is a widely spread metal, being ther... more Nickel is the major cause of allergic contact dermatitis. It is a widely spread metal, being therefore very difficult to avoid. Nickel cutaneous allergy can occur in occupational and non-occupational contexts and can result from direct cutaneous contact, systemic as well as airborne exposure. Such allergy can manifest with typical lesions of allergic contact dermatitis or with peculiar features such as follicular erythemato-micropapularvescicular lesions. Diagnosis of allergic contact dermatitis to nickel is based on patch testing, employing nickel sulfate 5% in petroleum jelly. Reactions to patch test have to be assessed at 48-72 hours, and up to 6 days. Nickel contact dermatitis can be managed with the traditional therapeutic approach used in allergic contact dermatitis. As of today, hyposensitization therapy with oral nickel represents to be the only treatment acting on the pathogenetic mechanisms of nickel allergy.
Papers by Domenico Bonamonte
Rapidly growing mycobacteria (RGM) are among the most common nontuberculous mycobacteria (NTM) as... more Rapidly growing mycobacteria (RGM) are among the most common nontuberculous mycobacteria (NTM) associated with cutaneous infections in industrialized countries [1–8].
The bovine tubercle bacillus must firstly be placed in context among the other agents of tubercul... more The bovine tubercle bacillus must firstly be placed in context among the other agents of tuberculosis [1–5]. In the early decades of the twentieth century, bacteriologists recognized four varieties of tubercle bacilli (human, bovine, avian and cold-blooded), depending on the life forms from which they were isolated. By the middle of the century, only two varieties were still recognized as agents of human and bovine tuberculosis (TB), namely Mycobacterium tuberculosis and M. bovis [6], respectively.
Mycobacterium scrofulaceum is a member of the Runyon class II scotochromogen acid-fast bacilli [1... more Mycobacterium scrofulaceum is a member of the Runyon class II scotochromogen acid-fast bacilli [1–3]. It is widely present in nature, but is now an infrequent human pathogen. It was first described in the 1950s [4–6] and the name likely derives from its isolation from cervical lymph nodes.
Cancers
Melanoma is reported as the 19th most common cancer worldwide, with estimated age-standardized in... more Melanoma is reported as the 19th most common cancer worldwide, with estimated age-standardized incidence rates of 2.8–3.1 per 100,000. Although the origin is most frequently cutaneous, mucosal melanoma has been described several times in literature, and despite its rarity (only 1% of all melanomas), increasing attention is being paid to this disease form. Within this subgroup, melanomas of the uropoetic apparatus are a rarity among rarities. Indeed, less than 50 cases of primary melanoma originating from the urinary bladder have been described, and even less originating from the kidney, renal pelvis and urethra. In this work, we present a detailed review of the literature related to this subclass of mucosal melanoma, delve into the biological landscape of this neoplasm and discuss current approaches, future perspectives and potential therapeutic approaches.
Plastic and Reconstructive Surgery - Global Open, Sep 1, 2017
Journal of Burn Care & Research
We present a case of symmetrical thermal intermediate-deep burns treated in a case-control fashio... more We present a case of symmetrical thermal intermediate-deep burns treated in a case-control fashion with the stromal vascular fraction (SVF) obtained with the MyStem™ device and a scaffold of hyaluronic acid. After enzymatic debridement and SVF harvesting and application, we observed quicker healing (as assessed by wound area histogram planimetry) in the case area as opposed to the control one, which eventually underwent skin grafting. At the 3 months follow-up, the Vancouver Scar Scale was 9 for the case side and 10 for the control side, with a tendency to hypertrophic scarring in both areas, while patient satisfaction Visual Analogue Scale was 7 for the case side and 2 for the control side. CD31 expression, a marker of neoangiogenesis, was significantly higher in the case area as compared to the control one. SVF could potentially represent a valid alternative to the current standard of care, with a decreased need of invasive surgery and consequent improved patients' quality of life.
Plastic and Reconstructive Surgery - Global Open
Plastic and Reconstructive Surgery - Global Open
Mycobacterial Skin Infections
Anais Brasileiros de Dermatologia, 2016
Contact Dermatitis
It is also possible that your web browser is not configured or not able to display style sheets. ... more It is also possible that your web browser is not configured or not able to display style sheets. In this case, although the visual presentation will be degraded, the site should continue to be functional. We recommend using the ...
Mycobacterium marinum lives in aquatic environments, where it causes disease in many poikilodermi... more Mycobacterium marinum lives in aquatic environments, where it causes disease in many poikilodermic fish species living in fresh or saltwater; the organism has a wide geographic distribution in the water world [1]. The first report of a mycobacterium isolated in fish (very likely M. marinum) is attributed to Bataillon and Coll., who isolated acid-fast bacilli, named M. piscium, in 1897, from a tuberculous lesion of a common carp (Cyprinus carpio) [2, 3]. Then in 1926 it was isolated and identified by Aronson from tubercles in various organs of marine fish found dead in the Philadelphia Aquarium [4]. Initially M. marinum was thought to infect fishes only and was named accordingly, but it is now known to be a ubiquitous species. The original freshwater isolate of M. piscium was quite possibly a variant of M. marinum. Other marine Mycobacterium species have been described in the literature, such as M. platypoecilus, M. anabanti, and M. balnei; however, comparative cultural, morphologica...
Clinical Contact Dermatitis
The Open Dermatology Journal
Airborne dermatoses are complaints linked to external environmental, chemical, and biotic agents ... more Airborne dermatoses are complaints linked to external environmental, chemical, and biotic agents carried through the air. In general, airborne dermatoses that are most common in the work environment, tend to cause diagnostic problems that are challenging for both the patient and the doctor. It should also be borne in mind that since the external culprit agents are present in the environment, they do not only come in contact with the skin and mucosa, but can also be inhaled or ingested, thus also causing respiratory and systemic symptoms. Among the various clinical forms, airborne contact dermatitis interests the parts of the body exposed to the air: face, neck, upper aspect of the chest, hands, wrists. These cases must be differentiated from photocontact dermatitis; in the latter case, however, shadowed anatomic areas, such as the upper eyelids, behind the ears, the submandibular region, and under the hair, are not affected.
The Open Dermatology Journal
The etiopathogenesis of the nummular eczema is not fully known. Various causative factors have be... more The etiopathogenesis of the nummular eczema is not fully known. Various causative factors have been proposed, and among these only a few studies investigate the relevance of contact allergy. Here, we present a case of nummular contact eczema in an 8-year-old allergic to perfumes. Since atopic dermatitis may also present with different clinical phenotypes, among which nummular eczema is quite frequent, the possible significant differences between non-atopic and atopic nummular diseases are considered. Based on the high incidence of contact sensitization in all cases of nummular eczema, it is recommended to perform patch tests for diagnostic-preventive purposes.
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Open Access by Domenico Bonamonte
Papers by Domenico Bonamonte