Objective: To evaluate metabolic parameters such as serum albumin levels and serum total protein ... more Objective: To evaluate metabolic parameters such as serum albumin levels and serum total protein and their correlation with hematologic index such as lymphopenia in hospitalized patients with laboratory confirmed COVID-19 infection. Material and Methods: This retrospective study was conducted in Department of Pathology, Pakistan Institute of Medical Sciences, from April 2020 to June 2020. Total 65 patients with confirmed RT-PCR for COVID-19 infection were tested for alterations in serum albumin and total protein levels, and association between these two parameters and the presence of lymphopenia was studied. Pearson chi-square test was applied to analyze statistical significance and a p value less than 0.05 was taken as significant. Results: Age range was from 18 to 90 years of age, with a mean age of 50.6 ± 16.3 years. The male patients were in majority as compared to females. Hypoalbuminemia (serum albumin < 3.5 g/dl) was observed in 77% patients and hypoproteinemia (serum tota...
Journal of Islamabad Medical & Dental College, 2019
Background: Meningiomas are slow growing intracranial and intraspinal neoplasms with a tendency t... more Background: Meningiomas are slow growing intracranial and intraspinal neoplasms with a tendency to recur locally. WHO grades them as I (benign), II (atypical) and III (anaplastic) in order of their increasing aggressiveness, based on histological parameters and brain parenchymal invasion. Progesterone receptors (PR) are more prevalent amongst the lower grade meningiomas. The objective of this study was to determine the immunohistochemical expression of progesterone receptors in meningiomas of different grades.Material and Methods: A total of 100 cases were selected over a period of 2.5 years. Three to five microns’ thick sections stained with Hematoxylin and Eosin were examined microscopically by a team of two Histopathologists and graded into grades I, II and III, according to 2016 WHO classification criteria. Another section of the original tumor was stained with progesterone receptor antibody using the conventional immunoperoxidase method. Stained slides were than examined by the...
Objective: To evaluate metabolic parameters such as serum albumin levels and serum total protein ... more Objective: To evaluate metabolic parameters such as serum albumin levels and serum total protein and their correlation with hematologic index such as lymphopenia in hospitalized patients with laboratory confirmed COVID-19 infection. Material and Methods: This retrospective study was conducted in Department of Pathology, Pakistan Institute of Medical Sciences, from April 2020 to June 2020. Total 65 patients with confirmed RT-PCR for COVID-19 infection were tested for alterations in serum albumin and total protein levels, and association between these two parameters and the presence of lymphopenia was studied. Pearson chi-square test was applied to analyze statistical significance and a p value less than 0.05 was taken as significant. Results: Age range was from 18 to 90 years of age, with a mean age of 50.6 ± 16.3 years. The male patients were in majority as compared to females. Hypoalbuminemia (serum albumin < 3.5 g/dl) was observed in 77% patients and hypoproteinemia (serum tota...
Journal of Islamabad Medical & Dental College, 2019
Background: Meningiomas are slow growing intracranial and intraspinal neoplasms with a tendency t... more Background: Meningiomas are slow growing intracranial and intraspinal neoplasms with a tendency to recur locally. WHO grades them as I (benign), II (atypical) and III (anaplastic) in order of their increasing aggressiveness, based on histological parameters and brain parenchymal invasion. Progesterone receptors (PR) are more prevalent amongst the lower grade meningiomas. The objective of this study was to determine the immunohistochemical expression of progesterone receptors in meningiomas of different grades.Material and Methods: A total of 100 cases were selected over a period of 2.5 years. Three to five microns’ thick sections stained with Hematoxylin and Eosin were examined microscopically by a team of two Histopathologists and graded into grades I, II and III, according to 2016 WHO classification criteria. Another section of the original tumor was stained with progesterone receptor antibody using the conventional immunoperoxidase method. Stained slides were than examined by the...
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Papers by Dr.Summaya Sohail