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      Estrogen ReceptorPhenotypeTriple Negative Breast CancerFenotipo
Systemic therapy for triple negative breast cancer (TNBC) is mostly based upon chemotherapy. Epithelial Growth Factor Receptor (EGFR) is overexpressed in around 50% of TNBC and may play a role in its pathogenesis. Consequently, we... more
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    • Triple Negative Breast Cancer
The aim of the study was to compare dosimetric parameters of planning target volume (PTV) and organs at risk (lungs) between 3D-conformal radiation therapy (3D CRT) and intensity-modulated radiation therapy (IMRT) in breast cancer, also... more
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    •   24  
      CancerBreast CancerComputer-Aided Detection and Diagnosis (CAD) for Breast CancerCancer Biology
Triple negative breast cancer (TNBC) is a subtype of breast tumor which comprises 24% of newly diagnosed tumors that lacks hormone receptor expression and HER2 gene amplification. This study illustrated the pathological features of triple... more
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    •   3  
      Breast CancerMolecular PathologyTriple Negative Breast Cancer
Breast cancer stem cells (BCSCs) represent a heterogeneous subpopulation of rare cells within breast cancer tumors, displaying an enhanced tumor initiating capability and underlying disease progression and therapy resistance. Unraveling... more
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    •   16  
      Health SciencesOncologyStem CellsCancer
The search for cytotoxic agents from marine natural products ultimately led to the production of eribulin, which is a synthetic macrocyclic ketone analog of halichondrin B. Eribulin binds to tubulin to induce mitotic arrest and gained... more
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    •   8  
      Breast CancerChemotherapyMedical OncologyBreast Cancer Research
Triple-negative breast cancer is a type of aggressive breast cancer without the immunohistochemical expression of estrogen receptors, progesterone receptors and human epidermal growth factor receptor-2; with poor prognosis, greater... more
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    • Triple Negative Breast Cancer
Citation: Hong Xiao, et al. (2016) Survival Analysis of Women with Triple Negative Breast Cancer Using EMR-Linked Cancer Registry Data in Florida. J Womens Health Gyn 1: 1-10. Abstract Background: Triple negative breast cancer (TNBC) is... more
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    •   4  
      Breast CancerElectronic Medical RecordsSurvivalTriple Negative Breast Cancer
Matrix-producing carcinoma (MPC) is an uncommon variant of metaplas-tic carcinoma. It was first described by Wargotz and Norris in 1989 as inva-sive breast carcinoma with direct transition to cartilaginous stroma without intervening... more
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    •   3  
      PathologyBreast CancerTriple Negative Breast Cancer
Context: Piper cubeba L. (family Piperaceae) is used traditionally for the treatment of many diseases, including cancer. Aims: To determine the anticancer activity of P. cubeba crude extracts on cancer cells and identify chemical... more
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    •   15  
      Traditional MedicineMedicinal PlantsApoptosisHerbal Medicine
Metabolic syndrome and type 2 diabetes are associated with increased risk of breast cancer development and progression. Methylglyoxal (MG), a glycolysis by-product, is generated through a non-enzymatic reaction from triose-phosphate... more
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    •   4  
      Breast Cancer ResearchTriple Negative Breast CancerMethylglyoxalcarbonyl stress
Observations on the role of ovarian hormones in breast cancer growth, as well as interest in contraception, stimulated research into the biology of estrogens. The identification of the classical receptors ERα and ERβ and the... more
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    •   15  
      Breast CancerComputer-Aided Detection and Diagnosis (CAD) for Breast CancerMolecular and Expression Analysis on Breast Cancer ResearchBreast, prostate, lung cancers
"A breast cancer is a malignant tumor that starts from cells of the breast. A malignant tumor is a group of cancer cells that may grow into (invade) surrounding tissues or spread (metastasize) to distant areas of the body. Breast... more
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    •   38  
      Breast CancerComputer-Aided Detection and Diagnosis (CAD) for Breast CancerEstrogen responsive breast cancerAndrogenesis
Objective: The fermented wheat germ extract, which is the active ingredient of nutraceuticals widely used by cancer patients in Europe, Korea and the United States, possesses cytotoxic and anti-metastatic effects in various human... more
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    •   13  
      OncologyNatural ProductsComplementary and Alternative MedicineCancer
Dear Sir/Madam We are currently hosting the Oncologist & Diagnostics Conference which is going to be organized during August 28-30, 2017 Brussels, Belgium. With great pride and honour, we would like to invite you to participate in... more
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    •   167  
      OncologyRadiologyCancer survivorship (Health Sciences)Oncology Informatics
Neural stem cells maintain their tumor tropism after internalizing gold nanorods. When exposed to a laser, the loaded cells heat up, destroying surrounding tumor cells.
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    •   6  
      Targeted Drug DeliveryNanomaterialsNanoparticlesTriple Negative Breast Cancer
Breast cancer (BC) is the most frequent cancer among women in the world and it remains a leading cause of cancer death in women globally. Among BCs, triple negative breast cancer (TNBC) is the most aggressive, and for its histochemical... more
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    •   5  
      Breast CancerTriple Negative Breast CancerRepositioningDrug Repurposing
Triple negative breast cancer TNBC is the type of breast cancer that does not have Estrogen receptor, Progesterone receptor and human epidermal growth factor receptors 2 (HER2) when stained with the Immunohistochemistry stains. As it's... more
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    •   8  
      IpilimumabTriple Negative Breast CancerCTLA-4TNBC
The purpose of this review article is to discuss the potential of T-type voltage gated calcium channels (VGCCs) as drug targets in breast cancer. Breast cancer, attributable to the different molecular subtypes, has a crucial need for... more
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    •   5  
      CancerBreast CancerTriple Negative Breast CancerVoltage-Gated Calcium Channels
Activating protein-1 (AP-1) family members, especially Fra-1 and c-Jun, are highly expressed in invasive cancers and can mediate enhanced migration and proliferation. The aim of this study was to explore the significance of elevated... more
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    •   10  
      CancerBiologyMetastasisMedicine
receptor-2 (HER2), which is suggested to be a reflection of absence of extensive glandular component. This cancer is considered as a subgroup of basal like breast cancers when classified by gene expression and carry a poor prognosis due... more
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    •   3  
      Breast CancerTriple Negative Breast CancerMetaplasticity
Training health workers in clinical breast examination for early detection of breast cancer in low-and middle-income countries. Training health workers in clinical breast examination for early detection of breast cancer in low-and... more
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    •   2  
      Breast Cancer ResearchTriple Negative Breast Cancer
Invitation Conference Series LLC welcomes you to attend the 2nd Cancer Diagnostics Conference & Expo during May 08-10, 2017 Barcelona, Spain. We cordially invite all the participants who are interested in sharing their knowledge and... more
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    •   118  
      Emergency MedicineInternal Medicine (General Medicine)OncologySports Medicine
To explain a bimodal pattern of hazard of relapse among early stage breast cancer patients identified in multiple databases, we proposed that late relapses result from steady stochastic progressions from single dormant malignant cells to... more
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    •   14  
      Breast CancerInflammationAngiogenesisComputer Simulation
Wnt/beta-catenin signaling has been suggested to be active in basal-like breast cancer. However, in highly aggressive metastatic triple-negative breast cancers (TNBC) the role of beta-catenin and the underlying mechanism(s) for the... more
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    •   3  
      Breast CancerWnt SignalingTriple Negative Breast Cancer
Recent advances in the development of cancer immunotherapy using immune checkpoint inhibitors against either programmed death receptor-1 (PD-1) or its ligand PD-L1 have revolutionized treatment of several solid tumors [1-4]. The... more
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    •   5  
      Breast CancerCancer ImmunotherapyImmunotherapyBreast Cancer Research
Cancer immunotherapy has evolved enormously in the recent years with better understanding of immune reactions, immune mi-croenvironment and immunosurveillance. Breast cancer is characterized by large heterogeneity, a fact which rather... more
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    •   5  
      Clinical TrialCancerBreast CancerImmunotherapy
Calculation of breast cancer area by an image analysis on mammography using thresholding method has been done.The mammography images ware taken from three sides of projection which include oblique (mlo), lateral (ml) and cranial caudal... more
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    •   22  
      Breast CancerComputer-Aided Detection and Diagnosis (CAD) for Breast CancerEstrogen responsive breast cancerMolecular and Expression Analysis on Breast Cancer Research
Dear Sir/Madam We are currently hosting the Oncologist & Diagnostics Conference which is going to be organized during August 28-30, 2017 Brussels, Belgium. With great pride and honour, we would like to invite you to participate in... more
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    •   104  
      OncologyRadiologyOncology InformaticsRadiation Oncology
Background: Breast cancer (BC) among Nigerians is characterised by high grade, triple negative, basal-like phenotype tumours with high proliferation indices and poor prognosis. The loss of Dicer expression has been speculated to play a... more
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    •   2  
      Triple Negative Breast CancerCancer Biomarkers
Introduction: In locally and locally advanced triple-negative breast cancer (TNBC), neoadjuvant chemotherapy (NAC) only induces a pCR in 30-35% of patients. Clinical and pathological factors are not enough to distinguish the patients who... more
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    •   6  
      OncologyBreast CancerChemotherapyMedicine
Triple negative breast cancer (TNBC) is a heterogeneous group of clinically aggressive breast cancers. TNBC patients have a high risk of recurrence and metastasis, and current treatment options remain limited. There is strong evidence... more
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    •   5  
      CancerBreast CancerCancer ResearchMedicine
Triple-negative breast cancer (TNBC) is a highly heterogeneous disease with multiple, distinct molecular subtypes that exhibit unique transcriptional programs and clinical progression trajectories. Despite knowledge of the molecular... more
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    •   6  
      AutophagyBiological SciencesMolecular and cellular biologyTriple Negative Breast Cancer
Triple-negative breast cancer (TNBC) is unresponsive to antiestrogen and anti-HER2 therapies, requiring the use of cytotoxic drug combinations of anthracyclines, taxanes, cyclophosphamide, and platinum compounds. Multidrug therapies... more
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    •   3  
      Cancer ChemotherapyTriple Negative Breast CancerAnthracyclines
TP53 gene is an effective predictor of all cancer types, including breast cancer. The use of neural network algorithms facilitates the detection and diagnosis of cancer through its training on mutations that occur in genes, such as the... more
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    •   9  
      Breast CancerComputer-Aided Detection and Diagnosis (CAD) for Breast CancerBreast Cancer Recurrence PreventiionFace Recognition System Based on Principal Component Analysis (PCA) with Back Propagation Neural Networks (BPNN)
INTRODUCTION : The breast cancer markers that are most important in determining therapy are estrogen receptor, progesterone receptor, and HER-2/neu. Clinicians evaluate clinical and pathologic staging and the expression of estrogen... more
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    •   2  
      Breast Cancer ResearchTriple Negative Breast Cancer
Triple negative breast carcinomas (TNBCs) are a group of primary breast tumors with aggressive clinical behavior that have no targeted therapy at present. Comparative studies for subtypes of triple negative group of invasive breast... more
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    •   6  
      PathologyOncologyBreast CancerMedical Oncology
Nowadays internet is becoming a platform where different user can post there ideas and opinions. The social networking sites and blogs offer a wide variety of such informative text which can be used to establish or determine a mindset for... more
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    •   3  
      Machine LearningData MiningTriple Negative Breast Cancer
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    •   2  
      Triple Negative Breast CancerBasal Like Breast Cancer
586Background: The goal of this Phase I/II trial is to assess the safety and efficacy of concurrent administration of durvalumab with weekly nab-paclitaxel (100 mg/m2) x 12 followed by dd AC x 4 as...
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    •   5  
      OncologyMedicineInternal MedicineClinical oncology
Purpose: As monotherapies, eribulin (chemotherapy) and pembrolizumab (immunotherapy) have shown promise for patients with metastatic triple-negative breast cancer (mTNBC). This phase Ib/II study examined eribulin plus pembrolizumab as a... more
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    •   7  
      OncologyMedicineInternal MedicineTriple Negative Breast Cancer
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    •   6  
      Breast CancerCancer ResearchMedicineTriple Negative Breast Cancer
Fcγ RIIA (CD32A) and their ligands, including the immunoglobulin Fc fragment and pentraxins, are key players in a variety of innate immune responses. Still unclear is whether additional ligands of CD32A do exist. The objective of this... more
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    •   18  
      BiosensorsBreast CancerCytotoxicityCancer Immunotherapy
Triple negative breast cancer (TNBC) is one of the most aggressive form of breast cancer (BC) with the highest mortality due to high rate of relapse, resistance, and lack of an effective treatment. Various molecular approaches have been... more
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    •   11  
      Machine LearningCancerBreast CancerCancer Biology
Trastuzumab emtansine (T-DM1) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugated to the microtubule-targeting agent emtansine (DM1). T-DM1 is an effective agent in the treatment of patients with... more
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    •   17  
      CancerBreast CancerCancer ResearchMitosis
Although greater than 90% of breast cancer-related mortality can be attributed to metastases, the molecular mechanisms underpinning the dissemination of primary breast tumor cells and their ability to establish malignant lesions in... more
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    •   7  
      Long Noncoding RnaMetastasisTriple Negative Breast CancerBorges
Wnt/b-catenin signalling has been suggested to be active in basal-like breast cancer. However, in highly aggressive metastatic triple-negative breast cancers (TNBC) the role of b-catenin and the underlying mechanism(s) for the... more
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    •   6  
      Breast CancerWnt SignalingBreast Cancer ResearchTriple Negative Breast Cancer
Cyclin E and its co-activator, phosphoecyclin-dependent kinase 2 (p-CDK2), regulate G 1 to S phase transition and their deregulation induces oncogenesis. Immunohistochemical assessments of these proteins in cancer have been reported but... more
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    •   3  
      Breast CancerBiomarkersTriple Negative Breast Cancer
To explain a bimodal pattern of hazard of relapse among early stage breast cancer patients identified in multiple databases, we proposed that late relapses result from steady stochastic progressions from single dormant malignant cells to... more
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    •   14  
      Breast CancerInflammationAngiogenesisComputer Simulation