Introduction: Malaria during pregnancy is a major public health concern and an important contribu... more Introduction: Malaria during pregnancy is a major public health concern and an important contributor to maternal and infant morbidity and mortality in malariaendemic countries. Pregnant women are particularly susceptible to malaria, and in low transmission settings they have a greater risk of severe Plasmodium falciparum malaria. Reviewing treatment protocol of pregnant women can put clear demarcation between safe and unsafe drugs there by prevent occurrence of abortion, still, birth, miscarriage in general avoid teratogenicity effect of drugs on fetus. Objective: The general objective of this review was to describe malaria treatment for pregnant women and to provide clinicians with up-to-date, evidence-based information on the treatment of malaria in pregnancy. Method: In this review it was examined the available information on the safety of antimalarials in pregnancy, from both animal and human studies. A literature search was performed using Medline (April 2016). Keywords used we...
Background Patient satisfaction is a widely used indicator to measure quality of pharmacy service... more Background Patient satisfaction is a widely used indicator to measure quality of pharmacy services. Currently, a transformational pharmacy service called auditable pharmaceutical transactions and services is being implemented nationally in Ethiopia. However, there is a dearth of evidence regarding the national impact of this system on patient satisfaction. Objective To assess patient satisfaction in hospital pharmacies that have implemented auditable pharmaceutical transactions and services in Ethiopia. Method This is a national study conducted based on a cross-sectional study design. Data were collected using a structured questionnaire from September 5 to October 5, 2020. The collected data was analyzed using spreadsheet excel and Statistical Package for the Social Sciences (SPSS) version 23. The proportions, ratios, and percentages were used for presenting data. A binary logistic regression test was used to determine the association of patient satisfaction with dispensary infrastr...
Advances in Pharmacoepidemiology and Drug Safety, 2018
Background: Multi-drug resistant tuberculosis is a widespread global problem. The magnitude of th... more Background: Multi-drug resistant tuberculosis is a widespread global problem. The magnitude of this disease varies significantly from country to country and the treatment outcomes are inadequately described in Ethiopia. Objective: To assess the survival status and risk factors for mortality of multidrug resistant tuberculosis patients at Adama and Bishoftu General Hospitals in Ethiopia. Methods: Retrospective cohort study design was conducted among multidrug resistant tuberculosis patients treated from May, 2013 to August, 2017 at Adama and Bishoftu General Hospitals. Data were collected using standardized data abstraction format. Data were analysed using STATA Version 13 statistical software. Risks were estimated for the entire follow-up time corresponding to each event occurrence using Kaplan-Meier method and the covariates were fitted to Cox Proportional Hazard Regression Model. Result: Among 164 patients, 74 (45.10%) were male and the mean age was 31.5 years. The participants we...
Background The use of herbal medicine is common among HIV/AIDS patients due to chronic nature of ... more Background The use of herbal medicine is common among HIV/AIDS patients due to chronic nature of the disease. However, the data are scarce on the extent of herbal medicine use and associated factors among HIV/AIDS patients while on antiretroviral therapy (ART) in Ethiopia. Purpose To assess the extent of herbal medicine use and associated factors among people living with HIV/AIDS on ART in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A cross-sectional study design was conducted from February to June 2019. Patients were interviewed face to face using a structured questionnaire. Binary analysis using a chi-square test was used to determine the independent association of herbal medicine use to demographic and clinical characteristics, and multivariate analysis using binary logistic regression was done to identify predictability of herbal medicine use adjusted for other factors. Results A total of 318 participants were included in this study of which 26.1% of patie...
Background Patient satisfaction is a widely used indicator to measure quality of pharmacy service... more Background Patient satisfaction is a widely used indicator to measure quality of pharmacy services. Currently, a transformational pharmacy service called auditable pharmaceutical transactions and services is being implemented nationally in Ethiopia. However, there is a dearth of evidence regarding the national impact of this system on patient satisfaction. Objective To assess patient satisfaction in hospital pharmacies that have implemented auditable pharmaceutical transactions and services in Ethiopia. Method This is a national study conducted based on a cross-sectional study design. Data were collected using a structured questionnaire from September 5 to October 5, 2020. The collected data was analyzed using spreadsheet excel and Statistical Package for the Social Sciences (SPSS) version 23. The proportions, ratios, and percentages were used for presenting data. A binary logistic regression test was used to determine the association of patient satisfaction with dispensary infrastr...
Background. Lipodystrophy is one of the clinical complications of insulin injection that affects ... more Background. Lipodystrophy is one of the clinical complications of insulin injection that affects insulin absorption and leads to poor glycemic control. Objective. To assess insulin-induced lipodystrophy and glycemic control. Methods. A cross sectional study was done on 176 diabetic children and adolescents who inject insulin for a minimum of one year. First, anthropometric and clinical characteristics of the patients were recorded in questionnaire, and then observation and palpation techniques were used in assessing lipodystrophy. Result. Out of the total 176 participants, 103 (58.5%) had insulin-induced lipodystrophy, of them 100 (97.1%) had lipohypertrophy and 3 (2.9%) had lipoatrophy. Being younger, failure to rotate the injection site every week and multiple reuse of insulin syringe had significant influence in development of insulin-induced lipohypertrophy. Lipohypertrophy in turn was associated with the use of higher dose of insulin and nonoptimal glycemic control. Conclusion....
Introduction: Malaria during pregnancy is a major public health concern and an important contribu... more Introduction: Malaria during pregnancy is a major public health concern and an important contributor to maternal and infant morbidity and mortality in malariaendemic countries. Pregnant women are particularly susceptible to malaria, and in low transmission settings they have a greater risk of severe Plasmodium falciparum malaria. Reviewing treatment protocol of pregnant women can put clear demarcation between safe and unsafe drugs there by prevent occurrence of abortion, still, birth, miscarriage in general avoid teratogenicity effect of drugs on fetus. Objective: The general objective of this review was to describe malaria treatment for pregnant women and to provide clinicians with up-to-date, evidence-based information on the treatment of malaria in pregnancy. Method: In this review it was examined the available information on the safety of antimalarials in pregnancy, from both animal and human studies. A literature search was performed using Medline (April 2016). Keywords used we...
Background Patient satisfaction is a widely used indicator to measure quality of pharmacy service... more Background Patient satisfaction is a widely used indicator to measure quality of pharmacy services. Currently, a transformational pharmacy service called auditable pharmaceutical transactions and services is being implemented nationally in Ethiopia. However, there is a dearth of evidence regarding the national impact of this system on patient satisfaction. Objective To assess patient satisfaction in hospital pharmacies that have implemented auditable pharmaceutical transactions and services in Ethiopia. Method This is a national study conducted based on a cross-sectional study design. Data were collected using a structured questionnaire from September 5 to October 5, 2020. The collected data was analyzed using spreadsheet excel and Statistical Package for the Social Sciences (SPSS) version 23. The proportions, ratios, and percentages were used for presenting data. A binary logistic regression test was used to determine the association of patient satisfaction with dispensary infrastr...
Advances in Pharmacoepidemiology and Drug Safety, 2018
Background: Multi-drug resistant tuberculosis is a widespread global problem. The magnitude of th... more Background: Multi-drug resistant tuberculosis is a widespread global problem. The magnitude of this disease varies significantly from country to country and the treatment outcomes are inadequately described in Ethiopia. Objective: To assess the survival status and risk factors for mortality of multidrug resistant tuberculosis patients at Adama and Bishoftu General Hospitals in Ethiopia. Methods: Retrospective cohort study design was conducted among multidrug resistant tuberculosis patients treated from May, 2013 to August, 2017 at Adama and Bishoftu General Hospitals. Data were collected using standardized data abstraction format. Data were analysed using STATA Version 13 statistical software. Risks were estimated for the entire follow-up time corresponding to each event occurrence using Kaplan-Meier method and the covariates were fitted to Cox Proportional Hazard Regression Model. Result: Among 164 patients, 74 (45.10%) were male and the mean age was 31.5 years. The participants we...
Background The use of herbal medicine is common among HIV/AIDS patients due to chronic nature of ... more Background The use of herbal medicine is common among HIV/AIDS patients due to chronic nature of the disease. However, the data are scarce on the extent of herbal medicine use and associated factors among HIV/AIDS patients while on antiretroviral therapy (ART) in Ethiopia. Purpose To assess the extent of herbal medicine use and associated factors among people living with HIV/AIDS on ART in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A cross-sectional study design was conducted from February to June 2019. Patients were interviewed face to face using a structured questionnaire. Binary analysis using a chi-square test was used to determine the independent association of herbal medicine use to demographic and clinical characteristics, and multivariate analysis using binary logistic regression was done to identify predictability of herbal medicine use adjusted for other factors. Results A total of 318 participants were included in this study of which 26.1% of patie...
Background Patient satisfaction is a widely used indicator to measure quality of pharmacy service... more Background Patient satisfaction is a widely used indicator to measure quality of pharmacy services. Currently, a transformational pharmacy service called auditable pharmaceutical transactions and services is being implemented nationally in Ethiopia. However, there is a dearth of evidence regarding the national impact of this system on patient satisfaction. Objective To assess patient satisfaction in hospital pharmacies that have implemented auditable pharmaceutical transactions and services in Ethiopia. Method This is a national study conducted based on a cross-sectional study design. Data were collected using a structured questionnaire from September 5 to October 5, 2020. The collected data was analyzed using spreadsheet excel and Statistical Package for the Social Sciences (SPSS) version 23. The proportions, ratios, and percentages were used for presenting data. A binary logistic regression test was used to determine the association of patient satisfaction with dispensary infrastr...
Background. Lipodystrophy is one of the clinical complications of insulin injection that affects ... more Background. Lipodystrophy is one of the clinical complications of insulin injection that affects insulin absorption and leads to poor glycemic control. Objective. To assess insulin-induced lipodystrophy and glycemic control. Methods. A cross sectional study was done on 176 diabetic children and adolescents who inject insulin for a minimum of one year. First, anthropometric and clinical characteristics of the patients were recorded in questionnaire, and then observation and palpation techniques were used in assessing lipodystrophy. Result. Out of the total 176 participants, 103 (58.5%) had insulin-induced lipodystrophy, of them 100 (97.1%) had lipohypertrophy and 3 (2.9%) had lipoatrophy. Being younger, failure to rotate the injection site every week and multiple reuse of insulin syringe had significant influence in development of insulin-induced lipohypertrophy. Lipohypertrophy in turn was associated with the use of higher dose of insulin and nonoptimal glycemic control. Conclusion....
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