Objective: A great number of surgical techniques have been described to improve the cosmetic outc... more Objective: A great number of surgical techniques have been described to improve the cosmetic outcome and reduce the complication rates of prominent ear. Our aim is to share our experience and results of our otoplasty technique, in which the anterior cartilage is ...
KBB-Forum: Elektronik Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi, 2007
Objective: A great number of surgical techniques have been described to improve the cosmetic outc... more Objective: A great number of surgical techniques have been described to improve the cosmetic outcome and reduce the complication rates of prominent ear. Our aim is to share our experience and results of our otoplasty technique, in which the anterior cartilage is ...
Objective: To investigate the geographical distribution of soldiers with chronic otitis media (CO... more Objective: To investigate the geographical distribution of soldiers with chronic otitis media (COM) and to analyse the aetiological factors contributing to differences. Materials and Methods: The records of soldiers who had been diagnosed with COM during ...
Background: Intraoperative injury to the internal carotid artery (ICA) during endoscopic sinus su... more Background: Intraoperative injury to the internal carotid artery (ICA) during endoscopic sinus surgery (ESS) or transnasal pituitary surgery is a rare but life-threatening complication. The medical literature was reviewed to determine the optimal management of carotid artery injury during endoscopic or microscopic transnasal surgery. Methods: The English medical literature was searched for articles from 1990 to 2005 that identified ICA injury during endoscopic sinus or trans-sphenoidal surgery. Articles were reviewed for number of patients, management of ICA injury, management of complications (pseudoaneurysm and carotid cavernous fistula), morbidity and mortality, and predisposing factors for ICA injury. Results: There were 69 cases of ICA injury including 29 pseudoaneurysms and 5 carotid-cavernous fistulas. The cavernous segment of the ICA was the most common site of injury during ESS or trans-sphenoidal pituitary surgery. ICA injury occurred in 10 patients during ESS with a mortality rate of 30%. ICA injury occurred in 1 patient during endoscopic pituitary surgery and was treated successfully. ICA injury occurred in 58 patients during trans-sphenoidal pituitary surgery with a mortality rate of 9% and a major neurological deficit in 10% (40 patients [69%] were treated successfully). Conclusions: Although injury to the ICA is a rare event with transnasal surgery, it has significant morbidity and mortality. Knowledge of endoscopic anatomy and good surgical technique help prevent injury. Most injuries can be effectively treated with modern interventional radiological techniques.
This study was aimed to evaluate the efficacy of treatment modalities for minimizing salivary gla... more This study was aimed to evaluate the efficacy of treatment modalities for minimizing salivary gland damage caused by radiotherapy. Forty rats were divided into five groups. Group 1 had no irradiation or any treatment. Group 2 underwent only 15 Gy single dose radiotherapy. N-acetylcysteine, dexamethasone, hyperbaric oxygen treatment were given, respectively to the group 3, 4 and 5 for 5 days. 15 Gy single dose radiotherapy was applied to the group 3, 4 and 5 on the second day. Pyknosis, lysis, and vacuolization were examined in ductal cells and pyknosis, lysis, vacuolization, inflammation and collective duct damage in acinar cells. Dexamethasone and hyperbaric oxygen did not prove to have a positive effect on acinar and ductal cell. N-acetylcysteine-applied group had statistically significantly lower amount of damage. We determined that the decrease of ductal and acinar cell damage in parotid glands of N-acetylcysteine-applied rats was more distinct and statistically.
Lipoid proteinosis is a rare autosomal recessive disorder characterized by a diffuse deposition o... more Lipoid proteinosis is a rare autosomal recessive disorder characterized by a diffuse deposition of hyaline material and lipids in the mucosa and dermis. Classical clinical features include skin scarring, beaded eyelid papules, and laryngeal infiltration leading to hoarseness. In this report, we describe three lipoid proteinosis cases with charasteristic lesions with varying degrees. There was a single parietal lobe calcification on cranial computed tomography of one patient. Histopathological examination of oral biopsy specimens showed submucosal deposits of periodic acid Schiff-positive, diastase resistant hyaline material corroborating the clinical diagnosis of lipoid proteinosis.
Objectives 1) To investigate the role of halofuginone hydrobromide on myringotomy incision healin... more Objectives 1) To investigate the role of halofuginone hydrobromide on myringotomy incision healing time. 2) To investigate the role of halofuginone hydrobromide on formation of myringosclerosis. Methods 40 rats with normal eardrums were involved in this study to determine if topical halofuginone application had an impact on prolonging the time for healing of myringotomy incision and its histopathological consequences. The study group and control group consisted of 30 and 10 rats, respectively. A posterior incision 1 mm in diameter was made on randomly selected healty eardrums of the rats. After making incision in the study group, gelfoam soaked in halofuginone hydrobromide of 30 mg/dl was applied on the perforation, while gelfoam dipped in isotonic saline was introduced to perforation in the control group. On days 1, 3,7,10,14,18,21, 24, 27 and 30, otoendoscopic evaluation of eardrums under general anesthesia was conducted and perforations were screened. On control days, one randoml...
Objective: A great number of surgical techniques have been described to improve the cosmetic outc... more Objective: A great number of surgical techniques have been described to improve the cosmetic outcome and reduce the complication rates of prominent ear. Our aim is to share our experience and results of our otoplasty technique, in which the anterior cartilage is ...
KBB-Forum: Elektronik Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi, 2007
Objective: A great number of surgical techniques have been described to improve the cosmetic outc... more Objective: A great number of surgical techniques have been described to improve the cosmetic outcome and reduce the complication rates of prominent ear. Our aim is to share our experience and results of our otoplasty technique, in which the anterior cartilage is ...
Objective: To investigate the geographical distribution of soldiers with chronic otitis media (CO... more Objective: To investigate the geographical distribution of soldiers with chronic otitis media (COM) and to analyse the aetiological factors contributing to differences. Materials and Methods: The records of soldiers who had been diagnosed with COM during ...
Background: Intraoperative injury to the internal carotid artery (ICA) during endoscopic sinus su... more Background: Intraoperative injury to the internal carotid artery (ICA) during endoscopic sinus surgery (ESS) or transnasal pituitary surgery is a rare but life-threatening complication. The medical literature was reviewed to determine the optimal management of carotid artery injury during endoscopic or microscopic transnasal surgery. Methods: The English medical literature was searched for articles from 1990 to 2005 that identified ICA injury during endoscopic sinus or trans-sphenoidal surgery. Articles were reviewed for number of patients, management of ICA injury, management of complications (pseudoaneurysm and carotid cavernous fistula), morbidity and mortality, and predisposing factors for ICA injury. Results: There were 69 cases of ICA injury including 29 pseudoaneurysms and 5 carotid-cavernous fistulas. The cavernous segment of the ICA was the most common site of injury during ESS or trans-sphenoidal pituitary surgery. ICA injury occurred in 10 patients during ESS with a mortality rate of 30%. ICA injury occurred in 1 patient during endoscopic pituitary surgery and was treated successfully. ICA injury occurred in 58 patients during trans-sphenoidal pituitary surgery with a mortality rate of 9% and a major neurological deficit in 10% (40 patients [69%] were treated successfully). Conclusions: Although injury to the ICA is a rare event with transnasal surgery, it has significant morbidity and mortality. Knowledge of endoscopic anatomy and good surgical technique help prevent injury. Most injuries can be effectively treated with modern interventional radiological techniques.
This study was aimed to evaluate the efficacy of treatment modalities for minimizing salivary gla... more This study was aimed to evaluate the efficacy of treatment modalities for minimizing salivary gland damage caused by radiotherapy. Forty rats were divided into five groups. Group 1 had no irradiation or any treatment. Group 2 underwent only 15 Gy single dose radiotherapy. N-acetylcysteine, dexamethasone, hyperbaric oxygen treatment were given, respectively to the group 3, 4 and 5 for 5 days. 15 Gy single dose radiotherapy was applied to the group 3, 4 and 5 on the second day. Pyknosis, lysis, and vacuolization were examined in ductal cells and pyknosis, lysis, vacuolization, inflammation and collective duct damage in acinar cells. Dexamethasone and hyperbaric oxygen did not prove to have a positive effect on acinar and ductal cell. N-acetylcysteine-applied group had statistically significantly lower amount of damage. We determined that the decrease of ductal and acinar cell damage in parotid glands of N-acetylcysteine-applied rats was more distinct and statistically.
Lipoid proteinosis is a rare autosomal recessive disorder characterized by a diffuse deposition o... more Lipoid proteinosis is a rare autosomal recessive disorder characterized by a diffuse deposition of hyaline material and lipids in the mucosa and dermis. Classical clinical features include skin scarring, beaded eyelid papules, and laryngeal infiltration leading to hoarseness. In this report, we describe three lipoid proteinosis cases with charasteristic lesions with varying degrees. There was a single parietal lobe calcification on cranial computed tomography of one patient. Histopathological examination of oral biopsy specimens showed submucosal deposits of periodic acid Schiff-positive, diastase resistant hyaline material corroborating the clinical diagnosis of lipoid proteinosis.
Objectives 1) To investigate the role of halofuginone hydrobromide on myringotomy incision healin... more Objectives 1) To investigate the role of halofuginone hydrobromide on myringotomy incision healing time. 2) To investigate the role of halofuginone hydrobromide on formation of myringosclerosis. Methods 40 rats with normal eardrums were involved in this study to determine if topical halofuginone application had an impact on prolonging the time for healing of myringotomy incision and its histopathological consequences. The study group and control group consisted of 30 and 10 rats, respectively. A posterior incision 1 mm in diameter was made on randomly selected healty eardrums of the rats. After making incision in the study group, gelfoam soaked in halofuginone hydrobromide of 30 mg/dl was applied on the perforation, while gelfoam dipped in isotonic saline was introduced to perforation in the control group. On days 1, 3,7,10,14,18,21, 24, 27 and 30, otoendoscopic evaluation of eardrums under general anesthesia was conducted and perforations were screened. On control days, one randoml...
Uploads
Papers by Hakan Cincik