Three different protocols for dental implantation: immediate (ImI), delayed (DI) and conventional... more Three different protocols for dental implantation: immediate (ImI), delayed (DI) and conventional (CI) were used. The primary stability is important for the secondary stability of implants. The purpose of the experiments was to monitor the stability of ImI, DI and CI following guided bone regeneration (GBR). A total of 18 implants were placed in the alveoli of 9 extracted premolars of the lower jaw of three mixed breed dogs. GBR was performed with a combination of Bio Oss® and Emdogain® and the Bio Gide® membrane. Control GBR was performed with coagulum and the same membrane. The stability of the implants was measured with Osstell® ISQ. The primary stability of the three types of implants was high, and differed statistically significantly (P<0.05). By the end of the first month after the placement, the stability of ImI and DI was reduced. The secondary stability of ImI and DI increased substantially (P<0.05) by the end of the third month both with regard to primary stability a...
Дисертационен труд за присъждане на образователна и научна степен "Доктор" /CD/ / Жерме... more Дисертационен труд за присъждане на образователна и научна степен "Доктор" /CD/ / Жермен Борисова Инджова . - София, 2015 . - 358 с. + Автореферат /CD/ ***** дисертация за придобиване на образователна и научна степен „Доктор“ Професионално направление 7.2. *** Докторска програма Хирургична стоматологияНаучни ръководители доц. д-р Ходор Ахмед Факих, дм доц. д-р Димитър Петков Сиврев, дм Рецензенти: Проф. д-р Христина Дянкова Михайлова, дм Проф. д-р Христо Николов Чучков, дм, дмн София, 2015
ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibu... more ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibular incisive canal (MIC) and its relation with the mental foramen (MF), by means of cone beam computed tomography (CBCT). The study material included 140 CBCT scans taken for preoperative planning of implant placement. CBCT data were examined carefully by three experienced observers for the presence and location of the initial part of the MIC and its relation with the ME. The inner diameter of the MIC at the beginning of the canal was measured three times by one observer. The interobserver agreement in identification of the MIC was excellent (mean kappa value of 0.84). A MIC was found in 92.9 % of cases. The mean inner vertical diameter of the canal was 1.44 mm +/- 0.39 mm. The diameter of the canal reached 2.5 mm at maximum. The canals in males and these on the right side of the mandibles were significantly wider The majority of the MICs-86.3 % (n = 195), began before the MF (type 1); the rest of them - 13.7 % (n = 31), began extremely close to the foramen (type 2). The MIC is an almost permanent finding on CBCT scans. In cases when the MIC begins at the level of the mental foramen (type 2) the lingual positioning of the implants could save the neurovascular bundle in the canal. All this will lead to better conditions for osteo integration and prevent eventual neurosensory disturbances.
ABSTRACT: Guided bone regeneration (GBR) is most effective when the material used has osteogenic,... more ABSTRACT: Guided bone regeneration (GBR) is most effective when the material used has osteogenic, osteoinductive and osteoconductive properties. Xenografts have limited biological properties, so a solution for diversification the properties of Bio Oss® was sought by combining with Emdogain®. The purpose of the present work was to study the process of GBR involving a combination of Bio Oss and Emdogain® compared with their independent use. An in vivo experiment was conducted with 10 New Zealand white rabbits. Artificial bone defects in the tibias and femurs of each rabbit were created. Depending of the used grafting materials, six experimental groups were formed: groups 1 and 2 (Bio Oss®); groups 3 and 4 (Emdogain®) and groups 5 and 6 (Bio Oss® + Emdogain®). In control groups (A and B), osseous coagulum was used as grafting material. Prior to apposition and soft tissue suturing, all bone defects were covered with Bio Gide® membrane. Half of the rabbits (groups 1, 3, 5 and contro...
Indjova, J., D. Sivrev, Kh. Fakih, M. Paskalev & Ts. Chaprazov, 2014. Repair of artificial bone d... more Indjova, J., D. Sivrev, Kh. Fakih, M. Paskalev & Ts. Chaprazov, 2014. Repair of artificial bone defects using guided bone regeneration with Bio Oss and enamel matrix derivative. I. Light microscopic study on long bones in rabbits. Bulg. J. Vet. Med., 17, No. 2, 134–146. Guided bone regeneration (GBR) is most effective when the material used has osteogenic, osteoinductive and osteoconductive properties. Xenografts have limited biological properties, so a solution for diversification the properties of Bio Oss® was sought by combining with Emdogain®. The purpose of the present work was to study the process of GBR involving a combination of Bio Oss and Emdogain® compared with their independent use. An in vivo experiment was conducted with 10 New Zealand white rabbits. Artificial bone defects in the tibias and femurs of each rabbit were created. Depending of the used grafting materials, six experimental groups were formed: groups 1 and 2 (Bio Oss®); groups 3 and 4 (Emdogain®) and groups 5 and 6 (Bio Oss® + Emdogain®). In control groups (A and B), osseous coagulum was used as grafting material. Prior to apposition and soft tissue suturing, all bone defects were covered with Bio Gide® membrane. Half of the rabbits (groups 1, 3, 5 and control group A) were euthanised at the end of the third, and groups 2, 4, 6 and control B – of the fourth month. There were no significant quality differences between experimental and control groups by the end of month 3 or 4. Osteoblasts, osteoclasts, osteoid and woven bone were found in all the samples studied. Maturing woven and lamellar bone were found in samples treated with Bio Oss® + Emdogain®. Newly formed bone was in close contact with Bio Oss® particles. Connective tissue around the Bio Oss® particles was found only in the groups in which it was the sole material used. There was neither evidence for degradation of Bio Oss® particles, nor for inflammation. The combination of osteoconductive properties of Bio Oss® with osteoinductive potential of Emdogain® benefited the formation of new woven bone, its transformation into lamellar and the osteointegration of Bio Oss® particles.
ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibu... more ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibular incisive canal (MIC) and its relation with the mental foramen (MF), by means of cone beam computed tomography (CBCT). The study material included 140 CBCT scans taken for preoperative planning of implant placement. CBCT data were examined carefully by three experienced observers for the presence and location of the initial part of the MIC and its relation with the ME. The inner diameter of the MIC at the beginning of the canal was measured three times by one observer. The interobserver agreement in identification of the MIC was excellent (mean kappa value of 0.84). A MIC was found in 92.9 % of cases. The mean inner vertical diameter of the canal was 1.44 mm +/- 0.39 mm. The diameter of the canal reached 2.5 mm at maximum. The canals in males and these on the right side of the mandibles were significantly wider The majority of the MICs-86.3 % (n = 195), began before the MF (type 1); the rest of them - 13.7 % (n = 31), began extremely close to the foramen (type 2). The MIC is an almost permanent finding on CBCT scans. In cases when the MIC begins at the level of the mental foramen (type 2) the lingual positioning of the implants could save the neurovascular bundle in the canal. All this will lead to better conditions for osteo integration and prevent eventual neurosensory disturbances.
Indjova, J., Kh. Fakih, D. Sivrev, D. Yovchev & Ts. Chaprazov, 2014. Stability of intraosse-ous d... more Indjova, J., Kh. Fakih, D. Sivrev, D. Yovchev & Ts. Chaprazov, 2014. Stability of intraosse-ous dental implants with guided bone regeneration (in vivo experiment in dogs). Bulg. J. Vet. Med., 17, No 1, 5060. Three different protocols for dental implantation: immediate (ImI), delayed (DI) and conventional (CI) were used. The primary stability is important for the secondary stability of implants. The purpose of the experiments was to monitor the stability of ImI, DI and CI following guided bone regeneration (GBR). A total of 18 implants were placed in the alveoli of 9 extracted premolars of the lower jaw of three mixed breed dogs. GBR was performed with a combination of Bio Oss ® and Emdogain ® and the Bio Gide ® membrane. Control GBR was performed with coagulum and the same membrane. The stability of the implants was measured with Osstell ® ISQ. The primary stability of the three types of implants was high, and differed statistically significantly (P<0.05). By the end of the first month after the placement, the stability of ImI and DI was reduced. The secondary stability of ImI and DI increased substantially (P<0.05) by the end of the third month both with regard to primary stability and stability by the end of the first month. The primary stability of intraosseous implants was a prerequisite for a high secondary stability. The decline in stability by the end of the first month after implantation was not an obstacle to achieve a high secondary stability.
Three different protocols for dental implantation: immediate (ImI), delayed (DI) and conventional... more Three different protocols for dental implantation: immediate (ImI), delayed (DI) and conventional (CI) were used. The primary stability is important for the secondary stability of implants. The purpose of the experiments was to monitor the stability of ImI, DI and CI following guided bone regeneration (GBR). A total of 18 implants were placed in the alveoli of 9 extracted premolars of the lower jaw of three mixed breed dogs. GBR was performed with a combination of Bio Oss® and Emdogain® and the Bio Gide® membrane. Control GBR was performed with coagulum and the same membrane. The stability of the implants was measured with Osstell® ISQ. The primary stability of the three types of implants was high, and differed statistically significantly (P<0.05). By the end of the first month after the placement, the stability of ImI and DI was reduced. The secondary stability of ImI and DI increased substantially (P<0.05) by the end of the third month both with regard to primary stability a...
Дисертационен труд за присъждане на образователна и научна степен "Доктор" /CD/ / Жерме... more Дисертационен труд за присъждане на образователна и научна степен "Доктор" /CD/ / Жермен Борисова Инджова . - София, 2015 . - 358 с. + Автореферат /CD/ ***** дисертация за придобиване на образователна и научна степен „Доктор“ Професионално направление 7.2. *** Докторска програма Хирургична стоматологияНаучни ръководители доц. д-р Ходор Ахмед Факих, дм доц. д-р Димитър Петков Сиврев, дм Рецензенти: Проф. д-р Христина Дянкова Михайлова, дм Проф. д-р Христо Николов Чучков, дм, дмн София, 2015
ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibu... more ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibular incisive canal (MIC) and its relation with the mental foramen (MF), by means of cone beam computed tomography (CBCT). The study material included 140 CBCT scans taken for preoperative planning of implant placement. CBCT data were examined carefully by three experienced observers for the presence and location of the initial part of the MIC and its relation with the ME. The inner diameter of the MIC at the beginning of the canal was measured three times by one observer. The interobserver agreement in identification of the MIC was excellent (mean kappa value of 0.84). A MIC was found in 92.9 % of cases. The mean inner vertical diameter of the canal was 1.44 mm +/- 0.39 mm. The diameter of the canal reached 2.5 mm at maximum. The canals in males and these on the right side of the mandibles were significantly wider The majority of the MICs-86.3 % (n = 195), began before the MF (type 1); the rest of them - 13.7 % (n = 31), began extremely close to the foramen (type 2). The MIC is an almost permanent finding on CBCT scans. In cases when the MIC begins at the level of the mental foramen (type 2) the lingual positioning of the implants could save the neurovascular bundle in the canal. All this will lead to better conditions for osteo integration and prevent eventual neurosensory disturbances.
ABSTRACT: Guided bone regeneration (GBR) is most effective when the material used has osteogenic,... more ABSTRACT: Guided bone regeneration (GBR) is most effective when the material used has osteogenic, osteoinductive and osteoconductive properties. Xenografts have limited biological properties, so a solution for diversification the properties of Bio Oss® was sought by combining with Emdogain®. The purpose of the present work was to study the process of GBR involving a combination of Bio Oss and Emdogain® compared with their independent use. An in vivo experiment was conducted with 10 New Zealand white rabbits. Artificial bone defects in the tibias and femurs of each rabbit were created. Depending of the used grafting materials, six experimental groups were formed: groups 1 and 2 (Bio Oss®); groups 3 and 4 (Emdogain®) and groups 5 and 6 (Bio Oss® + Emdogain®). In control groups (A and B), osseous coagulum was used as grafting material. Prior to apposition and soft tissue suturing, all bone defects were covered with Bio Gide® membrane. Half of the rabbits (groups 1, 3, 5 and contro...
Indjova, J., D. Sivrev, Kh. Fakih, M. Paskalev & Ts. Chaprazov, 2014. Repair of artificial bone d... more Indjova, J., D. Sivrev, Kh. Fakih, M. Paskalev & Ts. Chaprazov, 2014. Repair of artificial bone defects using guided bone regeneration with Bio Oss and enamel matrix derivative. I. Light microscopic study on long bones in rabbits. Bulg. J. Vet. Med., 17, No. 2, 134–146. Guided bone regeneration (GBR) is most effective when the material used has osteogenic, osteoinductive and osteoconductive properties. Xenografts have limited biological properties, so a solution for diversification the properties of Bio Oss® was sought by combining with Emdogain®. The purpose of the present work was to study the process of GBR involving a combination of Bio Oss and Emdogain® compared with their independent use. An in vivo experiment was conducted with 10 New Zealand white rabbits. Artificial bone defects in the tibias and femurs of each rabbit were created. Depending of the used grafting materials, six experimental groups were formed: groups 1 and 2 (Bio Oss®); groups 3 and 4 (Emdogain®) and groups 5 and 6 (Bio Oss® + Emdogain®). In control groups (A and B), osseous coagulum was used as grafting material. Prior to apposition and soft tissue suturing, all bone defects were covered with Bio Gide® membrane. Half of the rabbits (groups 1, 3, 5 and control group A) were euthanised at the end of the third, and groups 2, 4, 6 and control B – of the fourth month. There were no significant quality differences between experimental and control groups by the end of month 3 or 4. Osteoblasts, osteoclasts, osteoid and woven bone were found in all the samples studied. Maturing woven and lamellar bone were found in samples treated with Bio Oss® + Emdogain®. Newly formed bone was in close contact with Bio Oss® particles. Connective tissue around the Bio Oss® particles was found only in the groups in which it was the sole material used. There was neither evidence for degradation of Bio Oss® particles, nor for inflammation. The combination of osteoconductive properties of Bio Oss® with osteoinductive potential of Emdogain® benefited the formation of new woven bone, its transformation into lamellar and the osteointegration of Bio Oss® particles.
ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibu... more ABSTRACT The aim of this study was to assess the presence, width, and initial part of the mandibular incisive canal (MIC) and its relation with the mental foramen (MF), by means of cone beam computed tomography (CBCT). The study material included 140 CBCT scans taken for preoperative planning of implant placement. CBCT data were examined carefully by three experienced observers for the presence and location of the initial part of the MIC and its relation with the ME. The inner diameter of the MIC at the beginning of the canal was measured three times by one observer. The interobserver agreement in identification of the MIC was excellent (mean kappa value of 0.84). A MIC was found in 92.9 % of cases. The mean inner vertical diameter of the canal was 1.44 mm +/- 0.39 mm. The diameter of the canal reached 2.5 mm at maximum. The canals in males and these on the right side of the mandibles were significantly wider The majority of the MICs-86.3 % (n = 195), began before the MF (type 1); the rest of them - 13.7 % (n = 31), began extremely close to the foramen (type 2). The MIC is an almost permanent finding on CBCT scans. In cases when the MIC begins at the level of the mental foramen (type 2) the lingual positioning of the implants could save the neurovascular bundle in the canal. All this will lead to better conditions for osteo integration and prevent eventual neurosensory disturbances.
Indjova, J., Kh. Fakih, D. Sivrev, D. Yovchev & Ts. Chaprazov, 2014. Stability of intraosse-ous d... more Indjova, J., Kh. Fakih, D. Sivrev, D. Yovchev & Ts. Chaprazov, 2014. Stability of intraosse-ous dental implants with guided bone regeneration (in vivo experiment in dogs). Bulg. J. Vet. Med., 17, No 1, 5060. Three different protocols for dental implantation: immediate (ImI), delayed (DI) and conventional (CI) were used. The primary stability is important for the secondary stability of implants. The purpose of the experiments was to monitor the stability of ImI, DI and CI following guided bone regeneration (GBR). A total of 18 implants were placed in the alveoli of 9 extracted premolars of the lower jaw of three mixed breed dogs. GBR was performed with a combination of Bio Oss ® and Emdogain ® and the Bio Gide ® membrane. Control GBR was performed with coagulum and the same membrane. The stability of the implants was measured with Osstell ® ISQ. The primary stability of the three types of implants was high, and differed statistically significantly (P<0.05). By the end of the first month after the placement, the stability of ImI and DI was reduced. The secondary stability of ImI and DI increased substantially (P<0.05) by the end of the third month both with regard to primary stability and stability by the end of the first month. The primary stability of intraosseous implants was a prerequisite for a high secondary stability. The decline in stability by the end of the first month after implantation was not an obstacle to achieve a high secondary stability.
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