This study investigated the acute responses to volume-load-matched heavy-load (80% 1RM) versus li... more This study investigated the acute responses to volume-load-matched heavy-load (80% 1RM) versus light-load (40% 1RM) power-oriented resistance training sessions in well-functioning older adults. Using a randomized cross-over design, 15 volunteers completed each condition on a leg press. Neuromuscular (maximal isometric force and rate of force development) and functional performance (power during sit-to-stand test), lactate, and muscle damage biochemistry (creatine kinase, lactate dehydrogenase and C-reactive protein serum concentration) were assessed pre- and post-exercise. Performance declines were found after heavy-load (Cohen’s d effect size (d); maximal isometric force=0.95 d; rate of force development=1.17 d; sit-to-stand power =0.38 d, all p<0.05) and light-load (maximal isometric force=0.45 d; rate of force development=0.9 d; sit-to-stand power=1.17 d, all p<0.05), while lactate concentration increased only after light-load (1.7 d, p=0.001). However, no differences were ...
BackgroundPower-oriented resistance training (PRT) is one of the most effective exercise programs... more BackgroundPower-oriented resistance training (PRT) is one of the most effective exercise programs to counteract neuromuscular and physical function age-related declines. However, the optimal load that maximizes these outcomes or the load-specific adaptations induced on muscle power determinants remain to be better understood. Furthermore, to investigate whether these adaptations are potentially transferred to an untrained limb (i.e., cross-education phenomenon) could be especially relevant during limb-immobilization frequently observed in older people (e.g., after hip fracture).MethodsAt least 30 well-functioning older participants (>65 years) will participate in a within-person randomized controlled trial. After an 8-week control period, the effects of two 12-week PRT programs using light vs. heavy loads will be compared using an unilateral exercise model through three study arms (light-load PRT vs. non-exercise; heavy-load PRT vs. non-exercise; and light- vs. heavy- load PRT). ...
The actual mechanisms leading to a reduced muscle power and functional ability in older adults ar... more The actual mechanisms leading to a reduced muscle power and functional ability in older adults are poorly understood. We investigated the association between different force-velocity (F-V) profiles and impaired muscle power, physical and cognitive function, frailty, and health-related quality of life (HRQoL) in older people. Physical function (habitual gait speed, timed up-and-go test, sit-to-stand and stair-climbing ability), cognitive function, HRQoL and frailty were evaluated in 31 older subjects (70-85 years). The F-V relationship and maximal muscle power (P) were assessed in the leg press exercise. The skeletal muscle index (SMI) and fat index, moderate-to-vigorous physical activity (MVPA) and sedentary time were obtained from DXA scans and accelerometry, respectively. While some subjects showed a force deficit (F), others presented a velocity deficit (V), both leading to an impaired muscle power [Effect size (ES) = 1.30-1.44], and to a likely-very likely moderate harmful effec...
Journal of the American Medical Directors Association, Jan 13, 2017
Frailty is a strong predictor of adverse health events, but its impact on cognitive function is p... more Frailty is a strong predictor of adverse health events, but its impact on cognitive function is poorly understood. To assess cognitive performance in frailty and to identify the frailty stage where cognitive impairment begins. Data were taken from 2044 people aged ≥65 years without cognitive impairment selected from the Toledo Study for Healthy Aging, a population-based cohort of older adults. Frailty status was assessed by 3 different scales: Frailty Phenotype (FP), Frailty Trait Scale (FTS), and Frailty Index (FI). Neuropsychological assessments of different cognitive domains included the Mini-Mental State Examination, Short and Long-Term Memory Recalling Test, the Boston Naming Test, Verbal Fluency Test, Digit Span Forward, Go/No-go Test, Luria Orders Test, Clock Drawing Test, and Serial Word Learning Test. The relationships between the score of the scales and frailty status (robust, prefrail, and frail for FP and quartiles for FTS and FI) were analyzed using multivariate linear ...
L’objectif de cette thèse est de comprendre comment Luc Ferrari construit l'hétérogénéité de ... more L’objectif de cette thèse est de comprendre comment Luc Ferrari construit l'hétérogénéité de sa musique. Le compositeur conçoit la création comme un espace dans lequel, d'après ses mots, des idées qui n’ont pas « fatalement de liens entre elles » se rencontrent. L’œuvre devient alors un espace de cohabitation, de frottement, dans lequel d’autres composantes partagent l’espace avec « la musique », au sens étroit du terme. Avec les propositions lieu, récit et expériences, il sera question de tentatives pour caractériser ces composantes autres qui constituent l’hétérogène ferrarien. Dans la première partie, « musique et lieu », nous voyons comment les œuvres deviennent, par moments, des lieux. Des espaces réels, extérieurs, en rapport à un vécu. Á ce propos nous analyserons Hétérozygote. Dans la deuxième partie, « musique et récit », nous étudions l’importance que le compositeur donne à la narration dans ses œuvres, partant de sons anecdotiques jusqu’à l’évolution générale de s...
Outrigger Project Author: Jose Reyna (jose.reyna@cwu.edu) Co-Author: Tyler Hoffman (tyler.hoffman... more Outrigger Project Author: Jose Reyna (jose.reyna@cwu.edu) Co-Author: Tyler Hoffman (tyler.hoffman@cwu.edu) Mentors: Neil Hauff (hfhauff@gmail.com), Dr. Choi (Jeunghwan.choi@cwu.edu), Professor Pringle (Charles.pringle@cwu.edu), Professor Bramble (Tedman.bramble@cwu.edu), Dr. J (Craig.johnson@cwu.edu) Abstract Agricultural areas sometimes experience cold weather in early spring and risk damage to crops due to freezing. To combat this issue, farms can employ temporary fans to keep the blossoms from freezing. The design of a 17-foot-tall wind turbine mounted on 7-foot-wide trailer can help mix the warm air that’s above the wind turbine with the colder air that’s below to keep the crop from freezing. These wind turbines can produce up to 2000 lbs of thrust force. At a height of 17 feet, this force then becomes a moment of 34,000 lb-ft. This moment will tip the trailers over as they don’t cover a wide enough area to counter the moment. To counter this moment, telescoping outriggers were ...
L’objectif de cette these est de comprendre comment Luc Ferrari construit l'heterogeneite de ... more L’objectif de cette these est de comprendre comment Luc Ferrari construit l'heterogeneite de sa musique. Le compositeur concoit la creation comme un espace dans lequel, d'apres ses mots, des idees qui n’ont pas « fatalement de liens entre elles » se rencontrent. L’œuvre devient alors un espace de cohabitation, de frottement, dans lequel d’autres composantes partagent l’espace avec « la musique », au sens etroit du terme. Avec les propositions lieu, recit et experiences, il sera question de tentatives pour caracteriser ces composantes autres qui constituent l’heterogene ferrarien. Dans la premiere partie, « musique et lieu », nous voyons comment les œuvres deviennent, par moments, des lieux. Des espaces reels, exterieurs, en rapport a un vecu. A ce propos nous analyserons Heterozygote. Dans la deuxieme partie, « musique et recit », nous etudions l’importance que le compositeur donne a la narration dans ses œuvres, partant de sons anecdotiques jusqu’a l’evolution generale de s...
In Perspectives in Mexican American Studies, Vol. 1, 1988, "Readings in Southwestern Folklor... more In Perspectives in Mexican American Studies, Vol. 1, 1988, "Readings in Southwestern Folklore".
EL PSICOLOGO JOSE ANTONIO REYNA DICTO LA CONFERENCIA "ORIENTACION EN EDUCACION SEXUAL" ... more EL PSICOLOGO JOSE ANTONIO REYNA DICTO LA CONFERENCIA "ORIENTACION EN EDUCACION SEXUAL" EN LA ESCUELA NACIONAL DE ENFERMERIA Y OBSTETRICIA, EN LA QUE SE REFIRIO AL SIGNIFICADO DE LAS TEORIAS Y LAS CARACTERISTICAS QUE DEBEN REUNIR. ASIMISMO RECALCO QUE CUALQUIER TEORIA POR EL HECHO DE PERTENECER AL PLANO MENTAL NO ES TOTALMENTE EQUIPARABLE A LA PERSONA.
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve aro... more ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system, facilitator of amino acid transport, and the severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-CoV-2 receptor. ACE2 is widely expressed, including, in the lungs, cardiovascular system, gut, kidneys, central nervous system, and adipose tissue. ACE2 has recently been identified as the SARS-CoV-2 receptor, the infective agent responsible for coronavirus disease 2019, providing a critical link between immunity, inflammation, ACE2, and cardiovascular disease. Although sharing a close evolutionary relationship with SARS-CoV, the receptor-binding domain of SARS-CoV-2 differs in several key amino acid residues, allowing for stronger binding affinity with the human ACE2 receptor, which may account for the greater pathogenicity of SARS-CoV-2. The loss of ACE2 function following binding by SARS-CoV-2 i...
In this chapter, we introduce the concepts of digital forensics and experiential learning, and de... more In this chapter, we introduce the concepts of digital forensics and experiential learning, and describe how we implement experiential learning in an undergraduate level digital forensic course and a graduate level digital forensic course. The students were given the option of working on either a digital forensic research topic or the Digital Forensic Research Workshop (DFRWS) IoT Forensic Challenge (2018–2019). We also report on the artifacts generated by the students working on both types of final projects.
Skeletal muscle power has been demonstrated to be a stronger predictor of functional limitations ... more Skeletal muscle power has been demonstrated to be a stronger predictor of functional limitations than any other physical capability. However, no validated alternatives exist to the usually expensive instruments and/or time-consuming methods to evaluate muscle power in older populations. Our aim was to validate an easily applicable procedure to assess muscle power in large cohort studies and the clinical setting and to assess its association with other age-related outcomes. Forty community dwelling older adults (70-87 years) and 1804 older subjects (67-101 years) participating in the Toledo Study for Healthy Aging were included in this investigation. Sit-to-stand (STS) velocity and muscle power were calculated using the subject's body mass and height, chair height and the time needed to complete five STS repetitions, and compared with those obtained in the leg press exercise using a linear position transducer. In addition, STS performance, physical (gait speed) and cognitive func...
This study investigated the acute responses to volume-load-matched heavy-load (80% 1RM) versus li... more This study investigated the acute responses to volume-load-matched heavy-load (80% 1RM) versus light-load (40% 1RM) power-oriented resistance training sessions in well-functioning older adults. Using a randomized cross-over design, 15 volunteers completed each condition on a leg press. Neuromuscular (maximal isometric force and rate of force development) and functional performance (power during sit-to-stand test), lactate, and muscle damage biochemistry (creatine kinase, lactate dehydrogenase and C-reactive protein serum concentration) were assessed pre- and post-exercise. Performance declines were found after heavy-load (Cohen’s d effect size (d); maximal isometric force=0.95 d; rate of force development=1.17 d; sit-to-stand power =0.38 d, all p<0.05) and light-load (maximal isometric force=0.45 d; rate of force development=0.9 d; sit-to-stand power=1.17 d, all p<0.05), while lactate concentration increased only after light-load (1.7 d, p=0.001). However, no differences were ...
BackgroundPower-oriented resistance training (PRT) is one of the most effective exercise programs... more BackgroundPower-oriented resistance training (PRT) is one of the most effective exercise programs to counteract neuromuscular and physical function age-related declines. However, the optimal load that maximizes these outcomes or the load-specific adaptations induced on muscle power determinants remain to be better understood. Furthermore, to investigate whether these adaptations are potentially transferred to an untrained limb (i.e., cross-education phenomenon) could be especially relevant during limb-immobilization frequently observed in older people (e.g., after hip fracture).MethodsAt least 30 well-functioning older participants (>65 years) will participate in a within-person randomized controlled trial. After an 8-week control period, the effects of two 12-week PRT programs using light vs. heavy loads will be compared using an unilateral exercise model through three study arms (light-load PRT vs. non-exercise; heavy-load PRT vs. non-exercise; and light- vs. heavy- load PRT). ...
The actual mechanisms leading to a reduced muscle power and functional ability in older adults ar... more The actual mechanisms leading to a reduced muscle power and functional ability in older adults are poorly understood. We investigated the association between different force-velocity (F-V) profiles and impaired muscle power, physical and cognitive function, frailty, and health-related quality of life (HRQoL) in older people. Physical function (habitual gait speed, timed up-and-go test, sit-to-stand and stair-climbing ability), cognitive function, HRQoL and frailty were evaluated in 31 older subjects (70-85 years). The F-V relationship and maximal muscle power (P) were assessed in the leg press exercise. The skeletal muscle index (SMI) and fat index, moderate-to-vigorous physical activity (MVPA) and sedentary time were obtained from DXA scans and accelerometry, respectively. While some subjects showed a force deficit (F), others presented a velocity deficit (V), both leading to an impaired muscle power [Effect size (ES) = 1.30-1.44], and to a likely-very likely moderate harmful effec...
Journal of the American Medical Directors Association, Jan 13, 2017
Frailty is a strong predictor of adverse health events, but its impact on cognitive function is p... more Frailty is a strong predictor of adverse health events, but its impact on cognitive function is poorly understood. To assess cognitive performance in frailty and to identify the frailty stage where cognitive impairment begins. Data were taken from 2044 people aged ≥65 years without cognitive impairment selected from the Toledo Study for Healthy Aging, a population-based cohort of older adults. Frailty status was assessed by 3 different scales: Frailty Phenotype (FP), Frailty Trait Scale (FTS), and Frailty Index (FI). Neuropsychological assessments of different cognitive domains included the Mini-Mental State Examination, Short and Long-Term Memory Recalling Test, the Boston Naming Test, Verbal Fluency Test, Digit Span Forward, Go/No-go Test, Luria Orders Test, Clock Drawing Test, and Serial Word Learning Test. The relationships between the score of the scales and frailty status (robust, prefrail, and frail for FP and quartiles for FTS and FI) were analyzed using multivariate linear ...
L’objectif de cette thèse est de comprendre comment Luc Ferrari construit l'hétérogénéité de ... more L’objectif de cette thèse est de comprendre comment Luc Ferrari construit l'hétérogénéité de sa musique. Le compositeur conçoit la création comme un espace dans lequel, d'après ses mots, des idées qui n’ont pas « fatalement de liens entre elles » se rencontrent. L’œuvre devient alors un espace de cohabitation, de frottement, dans lequel d’autres composantes partagent l’espace avec « la musique », au sens étroit du terme. Avec les propositions lieu, récit et expériences, il sera question de tentatives pour caractériser ces composantes autres qui constituent l’hétérogène ferrarien. Dans la première partie, « musique et lieu », nous voyons comment les œuvres deviennent, par moments, des lieux. Des espaces réels, extérieurs, en rapport à un vécu. Á ce propos nous analyserons Hétérozygote. Dans la deuxième partie, « musique et récit », nous étudions l’importance que le compositeur donne à la narration dans ses œuvres, partant de sons anecdotiques jusqu’à l’évolution générale de s...
Outrigger Project Author: Jose Reyna (jose.reyna@cwu.edu) Co-Author: Tyler Hoffman (tyler.hoffman... more Outrigger Project Author: Jose Reyna (jose.reyna@cwu.edu) Co-Author: Tyler Hoffman (tyler.hoffman@cwu.edu) Mentors: Neil Hauff (hfhauff@gmail.com), Dr. Choi (Jeunghwan.choi@cwu.edu), Professor Pringle (Charles.pringle@cwu.edu), Professor Bramble (Tedman.bramble@cwu.edu), Dr. J (Craig.johnson@cwu.edu) Abstract Agricultural areas sometimes experience cold weather in early spring and risk damage to crops due to freezing. To combat this issue, farms can employ temporary fans to keep the blossoms from freezing. The design of a 17-foot-tall wind turbine mounted on 7-foot-wide trailer can help mix the warm air that’s above the wind turbine with the colder air that’s below to keep the crop from freezing. These wind turbines can produce up to 2000 lbs of thrust force. At a height of 17 feet, this force then becomes a moment of 34,000 lb-ft. This moment will tip the trailers over as they don’t cover a wide enough area to counter the moment. To counter this moment, telescoping outriggers were ...
L’objectif de cette these est de comprendre comment Luc Ferrari construit l'heterogeneite de ... more L’objectif de cette these est de comprendre comment Luc Ferrari construit l'heterogeneite de sa musique. Le compositeur concoit la creation comme un espace dans lequel, d'apres ses mots, des idees qui n’ont pas « fatalement de liens entre elles » se rencontrent. L’œuvre devient alors un espace de cohabitation, de frottement, dans lequel d’autres composantes partagent l’espace avec « la musique », au sens etroit du terme. Avec les propositions lieu, recit et experiences, il sera question de tentatives pour caracteriser ces composantes autres qui constituent l’heterogene ferrarien. Dans la premiere partie, « musique et lieu », nous voyons comment les œuvres deviennent, par moments, des lieux. Des espaces reels, exterieurs, en rapport a un vecu. A ce propos nous analyserons Heterozygote. Dans la deuxieme partie, « musique et recit », nous etudions l’importance que le compositeur donne a la narration dans ses œuvres, partant de sons anecdotiques jusqu’a l’evolution generale de s...
In Perspectives in Mexican American Studies, Vol. 1, 1988, "Readings in Southwestern Folklor... more In Perspectives in Mexican American Studies, Vol. 1, 1988, "Readings in Southwestern Folklore".
EL PSICOLOGO JOSE ANTONIO REYNA DICTO LA CONFERENCIA "ORIENTACION EN EDUCACION SEXUAL" ... more EL PSICOLOGO JOSE ANTONIO REYNA DICTO LA CONFERENCIA "ORIENTACION EN EDUCACION SEXUAL" EN LA ESCUELA NACIONAL DE ENFERMERIA Y OBSTETRICIA, EN LA QUE SE REFIRIO AL SIGNIFICADO DE LAS TEORIAS Y LAS CARACTERISTICAS QUE DEBEN REUNIR. ASIMISMO RECALCO QUE CUALQUIER TEORIA POR EL HECHO DE PERTENECER AL PLANO MENTAL NO ES TOTALMENTE EQUIPARABLE A LA PERSONA.
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve aro... more ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system, facilitator of amino acid transport, and the severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-CoV-2 receptor. ACE2 is widely expressed, including, in the lungs, cardiovascular system, gut, kidneys, central nervous system, and adipose tissue. ACE2 has recently been identified as the SARS-CoV-2 receptor, the infective agent responsible for coronavirus disease 2019, providing a critical link between immunity, inflammation, ACE2, and cardiovascular disease. Although sharing a close evolutionary relationship with SARS-CoV, the receptor-binding domain of SARS-CoV-2 differs in several key amino acid residues, allowing for stronger binding affinity with the human ACE2 receptor, which may account for the greater pathogenicity of SARS-CoV-2. The loss of ACE2 function following binding by SARS-CoV-2 i...
In this chapter, we introduce the concepts of digital forensics and experiential learning, and de... more In this chapter, we introduce the concepts of digital forensics and experiential learning, and describe how we implement experiential learning in an undergraduate level digital forensic course and a graduate level digital forensic course. The students were given the option of working on either a digital forensic research topic or the Digital Forensic Research Workshop (DFRWS) IoT Forensic Challenge (2018–2019). We also report on the artifacts generated by the students working on both types of final projects.
Skeletal muscle power has been demonstrated to be a stronger predictor of functional limitations ... more Skeletal muscle power has been demonstrated to be a stronger predictor of functional limitations than any other physical capability. However, no validated alternatives exist to the usually expensive instruments and/or time-consuming methods to evaluate muscle power in older populations. Our aim was to validate an easily applicable procedure to assess muscle power in large cohort studies and the clinical setting and to assess its association with other age-related outcomes. Forty community dwelling older adults (70-87 years) and 1804 older subjects (67-101 years) participating in the Toledo Study for Healthy Aging were included in this investigation. Sit-to-stand (STS) velocity and muscle power were calculated using the subject's body mass and height, chair height and the time needed to complete five STS repetitions, and compared with those obtained in the leg press exercise using a linear position transducer. In addition, STS performance, physical (gait speed) and cognitive func...
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