Mediterranean Journal of Hematology and Infectious Diseases
Background & objective: Sickle cell disease (SCD) is now a well-established cause of renal damage... more Background & objective: Sickle cell disease (SCD) is now a well-established cause of renal damage. In the northeast of the Democratic Republic of Congo (DRC), SCD is common. However, sickle cell nephropathy remains unstudied in this region. Thus, this study aimed to assess renal abnormalities in SCD patients in Kisangani (northeastern DRC). Methods: This cross-sectional study included 98 sickle cell patients selected from six health facilities in Kisangani and 89 healthy non-sickle cell subjects as the control group. Based on a survey form, a clinical examination and biological tests were performed to collect data related to the sex, age, weight, height, blood pressure, serum creatinine, serum uric acid, urinary albumin/creatinine ratio, and hemoglobin phenotype. We used a spectrophotometer to measure serum creatinine and uricemia, the sickle SCAN® device for hemoglobin phenotype, and an automatic multifunction analyzer for urine albumin/creatinine ratio. Data were entered into an E...
Prevalence of sickle cell trait is high in the Democratic Republic of Congo (DRC). Blood services... more Prevalence of sickle cell trait is high in the Democratic Republic of Congo (DRC). Blood services, therefore, face the risk of collecting blood units from donors with sickle cell trait.
Institut Supérieur des Techniques Médicales, Kindu, Maniema, République Démocratique du Congo. Dé... more Institut Supérieur des Techniques Médicales, Kindu, Maniema, République Démocratique du Congo. Département de Médecine Interne, Faculté de Médecine et de Pharmacie, Université de Kisangani, République Démocratique du Congo ; Département de Médecine Interne, Faculté de Médecine, Université de Kindu, République Démocratique du Congo; Département de santé publique, Faculté de Médecine et de Pharmacie, Université de Kisangani, République Démocratique du Congo ; Institut supérieur des techniques médicales de Tshumbe, République Démocratique du Congo.
Background Hepatitis B virus (HBV) and hepatitis C virus (HBV) infections accounts for substantia... more Background Hepatitis B virus (HBV) and hepatitis C virus (HBV) infections accounts for substantial proportions of the world wide liver disease. The two hepatotropic virus share common modes of transmission and their co-infection are common. Patients with dual HBV and HCV infection have more severe liver disease and are at increased risk of progression to hepatic cell carcinoma. This study was aimed to assess the prevalence of HBV and HCV among patients attending serology laboratory of Gondar University Teaching Hospital. Methods A retrospective study was conducted from January 2007 to December 2011 at serology laboratory of Gondar University Teaching Hospital. Data were cross checked for completeness, entered and analyzed using SPSS version 16 statistical package. Results From the total of 2,684 clinicaly suspected hepatitis patients, 563 (20.98%) were positive for HBsAg and anti-HCV test. Of all, 14.4% were seropositive for HBV (male= 7.89% female=6.27%) (p-value=0.011) while 12.4%...
Mediterranean Journal of Hematology and Infectious Diseases
Background & objective: Sickle cell disease (SCD) is now a well-established cause of renal damage... more Background & objective: Sickle cell disease (SCD) is now a well-established cause of renal damage. In the northeast of the Democratic Republic of Congo (DRC), SCD is common. However, sickle cell nephropathy remains unstudied in this region. Thus, this study aimed to assess renal abnormalities in SCD patients in Kisangani (northeastern DRC). Methods: This cross-sectional study included 98 sickle cell patients selected from six health facilities in Kisangani and 89 healthy non-sickle cell subjects as the control group. Based on a survey form, a clinical examination and biological tests were performed to collect data related to the sex, age, weight, height, blood pressure, serum creatinine, serum uric acid, urinary albumin/creatinine ratio, and hemoglobin phenotype. We used a spectrophotometer to measure serum creatinine and uricemia, the sickle SCAN® device for hemoglobin phenotype, and an automatic multifunction analyzer for urine albumin/creatinine ratio. Data were entered into an E...
Prevalence of sickle cell trait is high in the Democratic Republic of Congo (DRC). Blood services... more Prevalence of sickle cell trait is high in the Democratic Republic of Congo (DRC). Blood services, therefore, face the risk of collecting blood units from donors with sickle cell trait.
Institut Supérieur des Techniques Médicales, Kindu, Maniema, République Démocratique du Congo. Dé... more Institut Supérieur des Techniques Médicales, Kindu, Maniema, République Démocratique du Congo. Département de Médecine Interne, Faculté de Médecine et de Pharmacie, Université de Kisangani, République Démocratique du Congo ; Département de Médecine Interne, Faculté de Médecine, Université de Kindu, République Démocratique du Congo; Département de santé publique, Faculté de Médecine et de Pharmacie, Université de Kisangani, République Démocratique du Congo ; Institut supérieur des techniques médicales de Tshumbe, République Démocratique du Congo.
Background Hepatitis B virus (HBV) and hepatitis C virus (HBV) infections accounts for substantia... more Background Hepatitis B virus (HBV) and hepatitis C virus (HBV) infections accounts for substantial proportions of the world wide liver disease. The two hepatotropic virus share common modes of transmission and their co-infection are common. Patients with dual HBV and HCV infection have more severe liver disease and are at increased risk of progression to hepatic cell carcinoma. This study was aimed to assess the prevalence of HBV and HCV among patients attending serology laboratory of Gondar University Teaching Hospital. Methods A retrospective study was conducted from January 2007 to December 2011 at serology laboratory of Gondar University Teaching Hospital. Data were cross checked for completeness, entered and analyzed using SPSS version 16 statistical package. Results From the total of 2,684 clinicaly suspected hepatitis patients, 563 (20.98%) were positive for HBsAg and anti-HCV test. Of all, 14.4% were seropositive for HBV (male= 7.89% female=6.27%) (p-value=0.011) while 12.4%...
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