... de ДАРР Асаф (Darr, Asaf)старший преподаватель и руководитель Группы по изучению организаций... more ... de ДАРР Асаф (Darr, Asaf)старший преподаватель и руководитель Группы по изучению организаций в Университете Хайфы (Хайфа ... исследователей находятся создание и поддержание меж- личностных сетей (guanxi) в Китае [Yan 1996; Kipnis 1997], а также ...
... Sebastian Kohl 1 , Franz Kainer 2 , Wulf Schiefenhövel 3. ... London: Hogrth Press; 1969 17 T... more ... Sebastian Kohl 1 , Franz Kainer 2 , Wulf Schiefenhövel 3. ... London: Hogrth Press; 1969 17 Tan P C, Jacob R, Quek K F, Omar S Z. Pregnancy outcome in hyperemesis gravidarum and the effect of laboratory clinical indicators of hyperemesis severity. ...
The aim of this study was to determine whether cysteine-rich secretory protein 3 (CRISP3) express... more The aim of this study was to determine whether cysteine-rich secretory protein 3 (CRISP3) expression is linked to clinically or molecularly relevant subgroups of prostate cancer. A tissue microarray representing samples from >10,000 prostate cancers from radical prostatectomy specimens with clinical follow-up data were analyzed for CRISP3 expression by immunohistochemistry. CRISP3 expression was also compared with key genomic alterations of prostate cancer. CRISP3 staining was found as weak in 15%, moderate in 8.5%, and strong in 7.2% of prostate cancers, whereas no expression was detected in normal prostate. Strong CRISP3 expression was linked to advanced tumor stage, high Gleason score, and positive surgical margin status (P<0.0001 each). There was a marked accumulation of high CRISP3 expression in PTEN-deleted ERG-positive tumors (P<0.0001). A total of, 21.7% of ERG-positive and PTEN-deleted cancers had strong CRISP3 expression, but only 10.4% of ERG-positive cancers without PTEN deletion (P<0.0001). The rate of high CRISP3 expression was 2.5% in ERG-negative cancers (P=0.0001; vs ERG-positive cancers). Accordingly, CRISP3 overexpression was associated with early prostate-specific antigen recurrence in all tumors (P=0.0013) as well as in ERG-negative (P=0.004) and ERG-positive cancers (P=0.0318). CRISP3 expression did not retain prognostic significance in models also involving PTEN deletions. Strong CRISP3 expression is associated with unfavorable tumor phenotype and early recurrence in prostate cancers. The tight link of strong CRISP3 expression to the ERG fusion-positive prostate cancers with PTEN deletions provides further evidence for the existence of molecularly distinct subgroups of prostate cancers.
economic sociology_the european electronic newsletter, 2008
This short article is an introduction and a brief overview of economic geography. In addition, th... more This short article is an introduction and a brief overview of economic geography. In addition, the article aims to find out what sociologists can learn from geographers. There are two roots of economic geography. The first is economics and the second is geography (eg, Peet 2002; Barnes 2001), and the relation between the economists and the geographers can either be described in terms of rivalry, or in terms of a dialogue (Duranton/Storper 2006). Economics studies production, distribution, consumption and exchange. Geography studies man's ...
Economic Sociology: the European Electronic Newsletter, 2008
Due to the two traditions of the discipline, economics and geography, one may speak of a tension ... more Due to the two traditions of the discipline, economics and geography, one may speak of a tension within economic geography. This tension is even institutionalized; the Journal of Economic Geography, which is the economic geographyjournal with the highest impact factor, is divided into two parts—one run by economists and one run by geog-raphers. 1 Given that the field of economics was covered in the last Newsletter, we focus on the geographical branch of economic geography. Z
... de ДАРР Асаф (Darr, Asaf)старший преподаватель и руководитель Группы по изучению организаций... more ... de ДАРР Асаф (Darr, Asaf)старший преподаватель и руководитель Группы по изучению организаций в Университете Хайфы (Хайфа ... исследователей находятся создание и поддержание меж- личностных сетей (guanxi) в Китае [Yan 1996; Kipnis 1997], а также ...
... Sebastian Kohl 1 , Franz Kainer 2 , Wulf Schiefenhövel 3. ... London: Hogrth Press; 1969 17 T... more ... Sebastian Kohl 1 , Franz Kainer 2 , Wulf Schiefenhövel 3. ... London: Hogrth Press; 1969 17 Tan P C, Jacob R, Quek K F, Omar S Z. Pregnancy outcome in hyperemesis gravidarum and the effect of laboratory clinical indicators of hyperemesis severity. ...
The aim of this study was to determine whether cysteine-rich secretory protein 3 (CRISP3) express... more The aim of this study was to determine whether cysteine-rich secretory protein 3 (CRISP3) expression is linked to clinically or molecularly relevant subgroups of prostate cancer. A tissue microarray representing samples from >10,000 prostate cancers from radical prostatectomy specimens with clinical follow-up data were analyzed for CRISP3 expression by immunohistochemistry. CRISP3 expression was also compared with key genomic alterations of prostate cancer. CRISP3 staining was found as weak in 15%, moderate in 8.5%, and strong in 7.2% of prostate cancers, whereas no expression was detected in normal prostate. Strong CRISP3 expression was linked to advanced tumor stage, high Gleason score, and positive surgical margin status (P<0.0001 each). There was a marked accumulation of high CRISP3 expression in PTEN-deleted ERG-positive tumors (P<0.0001). A total of, 21.7% of ERG-positive and PTEN-deleted cancers had strong CRISP3 expression, but only 10.4% of ERG-positive cancers without PTEN deletion (P<0.0001). The rate of high CRISP3 expression was 2.5% in ERG-negative cancers (P=0.0001; vs ERG-positive cancers). Accordingly, CRISP3 overexpression was associated with early prostate-specific antigen recurrence in all tumors (P=0.0013) as well as in ERG-negative (P=0.004) and ERG-positive cancers (P=0.0318). CRISP3 expression did not retain prognostic significance in models also involving PTEN deletions. Strong CRISP3 expression is associated with unfavorable tumor phenotype and early recurrence in prostate cancers. The tight link of strong CRISP3 expression to the ERG fusion-positive prostate cancers with PTEN deletions provides further evidence for the existence of molecularly distinct subgroups of prostate cancers.
economic sociology_the european electronic newsletter, 2008
This short article is an introduction and a brief overview of economic geography. In addition, th... more This short article is an introduction and a brief overview of economic geography. In addition, the article aims to find out what sociologists can learn from geographers. There are two roots of economic geography. The first is economics and the second is geography (eg, Peet 2002; Barnes 2001), and the relation between the economists and the geographers can either be described in terms of rivalry, or in terms of a dialogue (Duranton/Storper 2006). Economics studies production, distribution, consumption and exchange. Geography studies man's ...
Economic Sociology: the European Electronic Newsletter, 2008
Due to the two traditions of the discipline, economics and geography, one may speak of a tension ... more Due to the two traditions of the discipline, economics and geography, one may speak of a tension within economic geography. This tension is even institutionalized; the Journal of Economic Geography, which is the economic geographyjournal with the highest impact factor, is divided into two parts—one run by economists and one run by geog-raphers. 1 Given that the field of economics was covered in the last Newsletter, we focus on the geographical branch of economic geography. Z
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