Case report on a 33 year old multiple sclerosis patient showing recurrent meningitis with an epis... more Case report on a 33 year old multiple sclerosis patient showing recurrent meningitis with an episode of rhinorrhea. The emphasis was put on the protein electrophoresis patterns.
... Record Details. Record ID, 289562. Record Type, journalArticle. Author, Luc Crevits [80100033... more ... Record Details. Record ID, 289562. Record Type, journalArticle. Author, Luc Crevits [801000331675] - Ghent University Luc.Crevits@UGent.be; Patrick Santens [801001011887] - Ghent University Patrick.Santens@UGent.be; Jacques De Reuck [801000166674] - Ghent ...
A case, which is clinically characterized by a subacute vertebrobasilar syndrome, is presented. T... more A case, which is clinically characterized by a subacute vertebrobasilar syndrome, is presented. The necropsy reveals multiple infarcts in brainstem, cerebellum and left cerebral hemisphere, due to tumoural emboli of a non-detected primary tumour. It is postulated that the latter has to originate in the lungs in order to produce this unique type of cerebral arterial embolism.
The influence of spatial-selective attention on the direction of the optokinetic nystagmus (OKN) ... more The influence of spatial-selective attention on the direction of the optokinetic nystagmus (OKN) was investigated in normal humans. During horizontal optokinetic stimulation of the peripheral retina, the central visual field was neutralized by ambivalent stimulation. The results showed that the direction of the OKN was modulated by the direction of the attention. A central mechanism that processes the optic information according to spatial-selective attention is proposed.
In a group of 33 patients with hemianopia, interhemispherical differences of the visually evoked ... more In a group of 33 patients with hemianopia, interhemispherical differences of the visually evoked potentials after pattern stimulation were studied. Both full field stimulation and vertical half field stimulation were applied. The results were not consistent, i.e. interhemispherical differences were not always according to the hemianopia. In general, with hemifield stimulation a better score was obtained. Differences between vascular accidents and tumours as the underlying cause of the hemianopia could not be established. With full-field stimulation and a midline electrode hemianopias could not reliably be detected.
Optokinetic nystagmus (OKN) was studied in patients with central visual field defects. Apart from... more Optokinetic nystagmus (OKN) was studied in patients with central visual field defects. Apart from a classic OKN, an inverted nystagmus was observed in some cases. A prerequisite for eliciting this paradoxic OKN was that the attention of the subject was directed to the field defect. Although other factors seem to be co-determining, a central mechanism is thought to process the visual information according to spatial-selective attention.
The hypothesis, derived from previous studies, that the off response forms the main part of the s... more The hypothesis, derived from previous studies, that the off response forms the main part of the second positive wave (P2) in the occipital response to the presentation of patterns was tested by using stimuli of various durations. It was found that the off response merges with P2 of the on response in the combined on-off response. The question, however, whether the on response or the off response contributes most to the combined on-off response could not be answered. By applying hemifield stimulation, the experiments furthermore confirm the concept of the presence of a double dipole in the hemisphere contralateral to the stimulated side.
We studied the clinicopathologic findings in four hypertensive patients with multiple leukomalaci... more We studied the clinicopathologic findings in four hypertensive patients with multiple leukomalacia, demyelinated lesions, and lacunar state. Only one patient had clinical evidence of dementia. The periventricular watershed infarcts were attributed to transient episodes of cardiac failure in brains with a compromised circulation in the territory of the deep perforating branches. These observations suggest that Binswanger encephalopathy does not differ from multi-infarct dementia.
We wanted to investigate to what extent patients with multiple sclerosis (MS), not complaining of... more We wanted to investigate to what extent patients with multiple sclerosis (MS), not complaining of dizziness or disequilibrium, may have problems with the estimation of gravidity. Therefore, we studied the static ‘subjective visual vertical’ (SVV), a test that is thought to reflect mainly otolith function. Further, we correlated SVV measures with the degree of disease disability. A group of outpatients was compared with a group of age‐ and sex‐matched healthy volunteers. The deviations of SVV in patients were significantly larger than in controls. Overall, SVV was abnormal in 48% of individual patients. There was a significant correlation between SVV and the global disability score. The same held true for correlation with the subscores of brainstem and cerebellar complaints. The SVV test proved to be a simple method that was well tolerated by the patients. It can be considered a complementary otoneurological tool for evaluating MS patients. Further, these findings suggest that misper...
... Record Details. Record ID, 274821. Record Type, journalArticle. Author, K Claeys; LucCrevits ... more ... Record Details. Record ID, 274821. Record Type, journalArticle. Author, K Claeys; LucCrevits [801000331675] - Ghent University Luc.Crevits@UGent.be; E Stuwen; Koen Van Der Goten [801000846381] - Ghent University; A Vandierendonck. ...
... Record Details. Record ID, 363185. Record Type, bookChapter. Author, Stefaan Lievens [0568456... more ... Record Details. Record ID, 363185. Record Type, bookChapter. Author, Stefaan Lievens [056845608703] - Ghent University; Luc Martens [801000462526] - Ghent University Luc.Martens@UGent.be; Luc Crevits [801000331675] - Ghent University Luc.Crevits@UGent. ...
To the Editor: The paper on idiopathic recurring stupor by Tinuper et al [1] is interesting becau... more To the Editor: The paper on idiopathic recurring stupor by Tinuper et al [1] is interesting because it opens new perspectives. However, we feel critical remarks are in order regarding both the presented electroclinical syndrome and the proposed etiology.
A fraction of cluster headache (CH) patients face diagnostic delay, misdiagnosis, undertreatment ... more A fraction of cluster headache (CH) patients face diagnostic delay, misdiagnosis, undertreatment and mismanagement. Specific data for Flanders are warranted. Data on CH characteristics, diagnostic process and treatment history were gathered using a self-administered questionnaire with 90 items in CH patients that presented to 4 neurology outpatient clinics. Data for 85 patients (77 men) with a mean age of 44 years (range 23-69) were analysed. 79% suffered from episodic CH and 21% from chronic CH. A mean diagnostic delay of 44 months was reported. 31% of patients had to wait more than 4 years for the CH diagnosis. 52% of patients consulted at least 3 physicians prior to CH diagnosis. Most common misdiagnoses were migraine (45%), sinusitis (23%), tooth/jaw problems (23%), tension-type headache (16%) and trigeminal neuralgia (16%). A significant percentage of patients had never received access to injectable sumatriptan (26%) or oxygen (31%). Most prescribed preventative drugs after the...
Case report on a 33 year old multiple sclerosis patient showing recurrent meningitis with an epis... more Case report on a 33 year old multiple sclerosis patient showing recurrent meningitis with an episode of rhinorrhea. The emphasis was put on the protein electrophoresis patterns.
... Record Details. Record ID, 289562. Record Type, journalArticle. Author, Luc Crevits [80100033... more ... Record Details. Record ID, 289562. Record Type, journalArticle. Author, Luc Crevits [801000331675] - Ghent University Luc.Crevits@UGent.be; Patrick Santens [801001011887] - Ghent University Patrick.Santens@UGent.be; Jacques De Reuck [801000166674] - Ghent ...
A case, which is clinically characterized by a subacute vertebrobasilar syndrome, is presented. T... more A case, which is clinically characterized by a subacute vertebrobasilar syndrome, is presented. The necropsy reveals multiple infarcts in brainstem, cerebellum and left cerebral hemisphere, due to tumoural emboli of a non-detected primary tumour. It is postulated that the latter has to originate in the lungs in order to produce this unique type of cerebral arterial embolism.
The influence of spatial-selective attention on the direction of the optokinetic nystagmus (OKN) ... more The influence of spatial-selective attention on the direction of the optokinetic nystagmus (OKN) was investigated in normal humans. During horizontal optokinetic stimulation of the peripheral retina, the central visual field was neutralized by ambivalent stimulation. The results showed that the direction of the OKN was modulated by the direction of the attention. A central mechanism that processes the optic information according to spatial-selective attention is proposed.
In a group of 33 patients with hemianopia, interhemispherical differences of the visually evoked ... more In a group of 33 patients with hemianopia, interhemispherical differences of the visually evoked potentials after pattern stimulation were studied. Both full field stimulation and vertical half field stimulation were applied. The results were not consistent, i.e. interhemispherical differences were not always according to the hemianopia. In general, with hemifield stimulation a better score was obtained. Differences between vascular accidents and tumours as the underlying cause of the hemianopia could not be established. With full-field stimulation and a midline electrode hemianopias could not reliably be detected.
Optokinetic nystagmus (OKN) was studied in patients with central visual field defects. Apart from... more Optokinetic nystagmus (OKN) was studied in patients with central visual field defects. Apart from a classic OKN, an inverted nystagmus was observed in some cases. A prerequisite for eliciting this paradoxic OKN was that the attention of the subject was directed to the field defect. Although other factors seem to be co-determining, a central mechanism is thought to process the visual information according to spatial-selective attention.
The hypothesis, derived from previous studies, that the off response forms the main part of the s... more The hypothesis, derived from previous studies, that the off response forms the main part of the second positive wave (P2) in the occipital response to the presentation of patterns was tested by using stimuli of various durations. It was found that the off response merges with P2 of the on response in the combined on-off response. The question, however, whether the on response or the off response contributes most to the combined on-off response could not be answered. By applying hemifield stimulation, the experiments furthermore confirm the concept of the presence of a double dipole in the hemisphere contralateral to the stimulated side.
We studied the clinicopathologic findings in four hypertensive patients with multiple leukomalaci... more We studied the clinicopathologic findings in four hypertensive patients with multiple leukomalacia, demyelinated lesions, and lacunar state. Only one patient had clinical evidence of dementia. The periventricular watershed infarcts were attributed to transient episodes of cardiac failure in brains with a compromised circulation in the territory of the deep perforating branches. These observations suggest that Binswanger encephalopathy does not differ from multi-infarct dementia.
We wanted to investigate to what extent patients with multiple sclerosis (MS), not complaining of... more We wanted to investigate to what extent patients with multiple sclerosis (MS), not complaining of dizziness or disequilibrium, may have problems with the estimation of gravidity. Therefore, we studied the static ‘subjective visual vertical’ (SVV), a test that is thought to reflect mainly otolith function. Further, we correlated SVV measures with the degree of disease disability. A group of outpatients was compared with a group of age‐ and sex‐matched healthy volunteers. The deviations of SVV in patients were significantly larger than in controls. Overall, SVV was abnormal in 48% of individual patients. There was a significant correlation between SVV and the global disability score. The same held true for correlation with the subscores of brainstem and cerebellar complaints. The SVV test proved to be a simple method that was well tolerated by the patients. It can be considered a complementary otoneurological tool for evaluating MS patients. Further, these findings suggest that misper...
... Record Details. Record ID, 274821. Record Type, journalArticle. Author, K Claeys; LucCrevits ... more ... Record Details. Record ID, 274821. Record Type, journalArticle. Author, K Claeys; LucCrevits [801000331675] - Ghent University Luc.Crevits@UGent.be; E Stuwen; Koen Van Der Goten [801000846381] - Ghent University; A Vandierendonck. ...
... Record Details. Record ID, 363185. Record Type, bookChapter. Author, Stefaan Lievens [0568456... more ... Record Details. Record ID, 363185. Record Type, bookChapter. Author, Stefaan Lievens [056845608703] - Ghent University; Luc Martens [801000462526] - Ghent University Luc.Martens@UGent.be; Luc Crevits [801000331675] - Ghent University Luc.Crevits@UGent. ...
To the Editor: The paper on idiopathic recurring stupor by Tinuper et al [1] is interesting becau... more To the Editor: The paper on idiopathic recurring stupor by Tinuper et al [1] is interesting because it opens new perspectives. However, we feel critical remarks are in order regarding both the presented electroclinical syndrome and the proposed etiology.
A fraction of cluster headache (CH) patients face diagnostic delay, misdiagnosis, undertreatment ... more A fraction of cluster headache (CH) patients face diagnostic delay, misdiagnosis, undertreatment and mismanagement. Specific data for Flanders are warranted. Data on CH characteristics, diagnostic process and treatment history were gathered using a self-administered questionnaire with 90 items in CH patients that presented to 4 neurology outpatient clinics. Data for 85 patients (77 men) with a mean age of 44 years (range 23-69) were analysed. 79% suffered from episodic CH and 21% from chronic CH. A mean diagnostic delay of 44 months was reported. 31% of patients had to wait more than 4 years for the CH diagnosis. 52% of patients consulted at least 3 physicians prior to CH diagnosis. Most common misdiagnoses were migraine (45%), sinusitis (23%), tooth/jaw problems (23%), tension-type headache (16%) and trigeminal neuralgia (16%). A significant percentage of patients had never received access to injectable sumatriptan (26%) or oxygen (31%). Most prescribed preventative drugs after the...
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