The preoperative evaluation of pulmonary sequestration requires delineation of the arterial suppl... more The preoperative evaluation of pulmonary sequestration requires delineation of the arterial supply and venous drainage of both the sequestered segment and the neighboring lung. In this case magnetic resonance imaging was the sole modality which demonstrated all components of the arterial and venous circulations of a sequestration and the remainder of the ipsilateral lung.
Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged ... more Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged fresh in vitro by high resolution magnetic resonance (MR) imaging with a surface coil. Following scanning, the specimens were fixed and sectioned in the same plane as the MR images. The prostate sections, corresponding to the MR images, were examined grossly and histologically for prostate pathology. Tissue characteristics were quantified by morphometric techniques and correlated with MR image intensity. Five prostates were normal and showed two distinct anatomic zones, a central periurethral zone and a peripheral zone. These two zones corresponded to two zones identified on MR of the five normal prostates. In contrast, both the MR images and the pathologic and morphometric studies of nine of the 10 prostates with benign prostatic hyperplasia (BPH) showed three distinct zones: a central region of BPH, a surrounding fibrous capsule, and a peripheral zone. This study suggests that there is a morphologic basis for MR intensity in the prostate.
Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic t... more Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic to the liver) previously treated with chemotherapy or radiotherapy or both in an attempt to reduce tumor bulk prior to surgical resection were examined by CT angiography (CTA). Areas of abnormal enhancement and irregular vessels simulating tumor involvement proved to be free of neoplasm at surgery. Perfusion abnormalities and vascular irregularity on CTA following radiotherapy or chemotherapy should not be automatically considered as neoplastic. Tissue confirmation in such cases should be obtained to rule out treatment related hepatic parenchymal changes.
The preoperative evaluation of pulmonary sequestration requires delineation of the arterial suppl... more The preoperative evaluation of pulmonary sequestration requires delineation of the arterial supply and venous drainage of both the sequestered segment and the neighboring lung. In this case magnetic resonance imaging was the sole modality which demonstrated all components of the arterial and venous circulations of a sequestration and the remainder of the ipsilateral lung.
Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic t... more Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic to the liver) previously treated with chemotherapy or radiotherapy or both in an attempt to reduce tumor bulk prior to surgical resection were examined by CT angiography (CTA). Areas of abnormal enhancement and irregular vessels simulating tumor involvement proved to be free of neoplasm at surgery. Perfusion abnormalities and vascular irregularity on CTA following radiotherapy or chemotherapy should not be automatically considered as neoplastic. Tissue confirmation in such cases should be obtained to rule out treatment related hepatic parenchymal changes.
Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged ... more Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged fresh in vitro by high resolution magnetic resonance (MR) imaging with a surface coil. Following scanning, the specimens were fixed and sectioned in the same plane as the MR images. The prostate sections, corresponding to the MR images, were examined grossly and histologically for prostate pathology. Tissue characteristics were quantified by morphometric techniques and correlated with MR image intensity. Five prostates were normal and showed two distinct anatomic zones, a central periurethral zone and a peripheral zone. These two zones corresponded to two zones identified on MR of the five normal prostates. In contrast, both the MR images and the pathologic and morphometric studies of nine of the 10 prostates with benign prostatic hyperplasia (BPH) showed three distinct zones: a central region of BPH, a surrounding fibrous capsule, and a peripheral zone. This study suggests that there is a morphologic basis for MR intensity in the prostate.
The preoperative evaluation of pulmonary sequestration requires delineation of the arterial suppl... more The preoperative evaluation of pulmonary sequestration requires delineation of the arterial supply and venous drainage of both the sequestered segment and the neighboring lung. In this case magnetic resonance imaging was the sole modality which demonstrated all components of the arterial and venous circulations of a sequestration and the remainder of the ipsilateral lung.
Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged ... more Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged fresh in vitro by high resolution magnetic resonance (MR) imaging with a surface coil. Following scanning, the specimens were fixed and sectioned in the same plane as the MR images. The prostate sections, corresponding to the MR images, were examined grossly and histologically for prostate pathology. Tissue characteristics were quantified by morphometric techniques and correlated with MR image intensity. Five prostates were normal and showed two distinct anatomic zones, a central periurethral zone and a peripheral zone. These two zones corresponded to two zones identified on MR of the five normal prostates. In contrast, both the MR images and the pathologic and morphometric studies of nine of the 10 prostates with benign prostatic hyperplasia (BPH) showed three distinct zones: a central region of BPH, a surrounding fibrous capsule, and a peripheral zone. This study suggests that there is a morphologic basis for MR intensity in the prostate.
Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic t... more Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic to the liver) previously treated with chemotherapy or radiotherapy or both in an attempt to reduce tumor bulk prior to surgical resection were examined by CT angiography (CTA). Areas of abnormal enhancement and irregular vessels simulating tumor involvement proved to be free of neoplasm at surgery. Perfusion abnormalities and vascular irregularity on CTA following radiotherapy or chemotherapy should not be automatically considered as neoplastic. Tissue confirmation in such cases should be obtained to rule out treatment related hepatic parenchymal changes.
The preoperative evaluation of pulmonary sequestration requires delineation of the arterial suppl... more The preoperative evaluation of pulmonary sequestration requires delineation of the arterial supply and venous drainage of both the sequestered segment and the neighboring lung. In this case magnetic resonance imaging was the sole modality which demonstrated all components of the arterial and venous circulations of a sequestration and the remainder of the ipsilateral lung.
Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic t... more Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic to the liver) previously treated with chemotherapy or radiotherapy or both in an attempt to reduce tumor bulk prior to surgical resection were examined by CT angiography (CTA). Areas of abnormal enhancement and irregular vessels simulating tumor involvement proved to be free of neoplasm at surgery. Perfusion abnormalities and vascular irregularity on CTA following radiotherapy or chemotherapy should not be automatically considered as neoplastic. Tissue confirmation in such cases should be obtained to rule out treatment related hepatic parenchymal changes.
Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged ... more Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged fresh in vitro by high resolution magnetic resonance (MR) imaging with a surface coil. Following scanning, the specimens were fixed and sectioned in the same plane as the MR images. The prostate sections, corresponding to the MR images, were examined grossly and histologically for prostate pathology. Tissue characteristics were quantified by morphometric techniques and correlated with MR image intensity. Five prostates were normal and showed two distinct anatomic zones, a central periurethral zone and a peripheral zone. These two zones corresponded to two zones identified on MR of the five normal prostates. In contrast, both the MR images and the pathologic and morphometric studies of nine of the 10 prostates with benign prostatic hyperplasia (BPH) showed three distinct zones: a central region of BPH, a surrounding fibrous capsule, and a peripheral zone. This study suggests that there is a morphologic basis for MR intensity in the prostate.
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