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Mayara Silva Marques

    Mayara Silva Marques

    Introduction Posterior Circulation (PC) stroke represents one-fifth of all ischemic strokes, with peculiar physiological characteristics. Hemorrhagic Transformation (HT) is a dreaded complication among stroke patients. Many predictive... more
    Introduction Posterior Circulation (PC) stroke represents one-fifth of all ischemic strokes, with peculiar physiological characteristics. Hemorrhagic Transformation (HT) is a dreaded complication among stroke patients. Many predictive scores of this complication have been proposed, but none is designed specifically for PC stroke patients – therefore, patients who are not eligible to reperfusion therapies (RT) represent about 80% of hospitalized cases. We propose a scoring system to assess the HT risk in PC stroke patients not submitted to RT. Methods We retrospectively evaluated data of patients diagnosed with PC stroke not treated with RT from 5 Comprehensive Stroke Centers (four in Brazil, 1 in the US) from 2015 to 2018. All patients underwent CT scan or MRI at admission and a follow-up neuroimaging within seven days. Independent variables identified in a logistic regression analysis were used to produce a predictive grading score.Results We included 952 patients in the final anal...
    Abstract Objective: to report a typical case of Periodic fever associated with aphthous stomatitis, pharyngitis and adenitis (PFAPA); review its characteristics and how to diagnose it in an emergency service. Case report: female patient,... more
    Abstract
    Objective: to report a typical case of Periodic fever associated with aphthous stomatitis, pharyngitis and adenitis (PFAPA); review its characteristics and how to diagnose it in an emergency service.
    Case report: female patient, 1 year and 5 months old, presented with recurrent episodes of fever, irritability and lesions of the oral mucosa. The symptoms last for a week and occur monthly since the patient was five months old. Other diseases were excluded and the patient was treated with prednisone during the episodes with improvement of symptoms.
    Conclusion: there are several auto-inflammatory diseases described, but the PFAPA is distinguished not only for being the most frequent, but also for being sporadic and for benign nature. The PFAPA is a relatively newly described syndrome that requires dissemination in academic circles leading to a higher index of suspicion among physicians and pediatricians, especially those who take care of patients in the emergency room avoiding unnecessary treatments and evaluation.
    Key words: periodic fever, Auto-inflammatory diseases, stomatitis, pharyngitis, lymphadenopathy