Proceedings of the 8th International Symposium NUMOG VIII, Rome, Italy, 10-12 April 2002, 2002
ABSTRACT The complexity of the stress field generated in a soil during a pressuremeter test can l... more ABSTRACT The complexity of the stress field generated in a soil during a pressuremeter test can lead to a partial drainage in front of the probe. The importance of this drainage depends on the radial permeability of the soil and also the strain rate of the test. The aim of this paper is to investigate the influence of the permeability on the test result. This study was undertaken using finite elements code CESAR_LCPC. The soil behaviour was modelled by the Modified Cam-Clay model. A particular attention was given on permeability effect on the distribution of stresses and on the stress path followed in the pressuremeter test. From these numerical results, three test conditions were identified: drained, partially drained and undrained condition.
Abstract. The creep behaviour of Zircaloy-4 with and without thermally-grown oxide at the surface... more Abstract. The creep behaviour of Zircaloy-4 with and without thermally-grown oxide at the surface is studied. It is particularly shown that the creep mechanism is guided by the metallic substrate in both cases: oxide scale is only responsible for a shift of the creep curves. ...
The objective of this study was to analyze the radiologic features of atypical forms of squamous ... more The objective of this study was to analyze the radiologic features of atypical forms of squamous cell cancer and correlate them with clinical, endoscopic, and histopathologic findings. The CT and MRI images of 31 patients with atypical forms of squamous cell carcinoma were reviewed retrospectively and the radiologic findings were correlated with clinical, endoscopic, and histopathologic findings. Histopathologic diagnoses included undifferentiated carcinoma of nasopharyngeal type (n = 8), verrucous carcinoma (n = 18), spindle cell carcinoma (n = 3), and basaloid cell carcinoma (n = 2). Undifferentiated carcinoma of nasopharyngeal type was located in the supraglottis or piriform sinus beneath an intact mucosa and initial endoscopic biopsy was most often negative. The discrepancy between an intact mucosa at endoscopy and a solid mass with homogenous enhancement at CT or MRI was characteristic for these tumors and warranted further investigations to obtain the definitive histologic diagnosis. Verrucous carcinoma displayed characteristic clinical, radiologic, and pathologic features, namely, an exophytic tumor arising from the glottic level displaying a rugged surface with finger-like projections but with only minor submucosal infiltration. Spindle cell carcinoma appeared as a polypoid mass with a thin stalk arising from the supraglottis. Basaloid cell carcinoma displayed a distinct lobulated enhancement pattern which was observed on contrast-enhanced T1-weighted SE images. Although the MR and CT features of atypical forms of squamous cell carcinoma cannot be considered pathognomonic they should raise the differential diagnosis even if endoscopic biopsy has been negative. The radiologist's awareness of the appearance of these unusual tumors on CT and MR images may greatly facilitate the diagnostic work-up and helps to guide the endoscopist to the adequate biopsy site in order to establish the correct diagnosis.
We evaluated the efficacy of N-Acetyl-Aspartyl-Glutamic acid (magnesium salt) (NAAGA) eye-drops i... more We evaluated the efficacy of N-Acetyl-Aspartyl-Glutamic acid (magnesium salt) (NAAGA) eye-drops in preventing the conjunctival and uveal allergic inflammation induced by reverse passive Arthus reaction in the rabbit. The permeability of the blood-conjunctival and blood-aqueous barriers was investigated by the leakage of 125I-labelled rabbit serum albumin injected intravenously prior to the challenge with the antigen. Permeability of both barriers was markedly increased 2 hours after the triggering of the allergic reaction; marked edema of the conjunctiva was also observed. Pretreatment with 1, 3, 6% (w/w) NAAGA eye-drops prevented the conjunctival inflammatory changes in a dose related manner and to a lesser degree, the breakdown of the blood-aqueous barrier. The distribution of topically applied 14C-NAAGA in the rabbit eyes was also investigated.
Proceedings of the 8th International Symposium NUMOG VIII, Rome, Italy, 10-12 April 2002, 2002
ABSTRACT The complexity of the stress field generated in a soil during a pressuremeter test can l... more ABSTRACT The complexity of the stress field generated in a soil during a pressuremeter test can lead to a partial drainage in front of the probe. The importance of this drainage depends on the radial permeability of the soil and also the strain rate of the test. The aim of this paper is to investigate the influence of the permeability on the test result. This study was undertaken using finite elements code CESAR_LCPC. The soil behaviour was modelled by the Modified Cam-Clay model. A particular attention was given on permeability effect on the distribution of stresses and on the stress path followed in the pressuremeter test. From these numerical results, three test conditions were identified: drained, partially drained and undrained condition.
Abstract. The creep behaviour of Zircaloy-4 with and without thermally-grown oxide at the surface... more Abstract. The creep behaviour of Zircaloy-4 with and without thermally-grown oxide at the surface is studied. It is particularly shown that the creep mechanism is guided by the metallic substrate in both cases: oxide scale is only responsible for a shift of the creep curves. ...
The objective of this study was to analyze the radiologic features of atypical forms of squamous ... more The objective of this study was to analyze the radiologic features of atypical forms of squamous cell cancer and correlate them with clinical, endoscopic, and histopathologic findings. The CT and MRI images of 31 patients with atypical forms of squamous cell carcinoma were reviewed retrospectively and the radiologic findings were correlated with clinical, endoscopic, and histopathologic findings. Histopathologic diagnoses included undifferentiated carcinoma of nasopharyngeal type (n = 8), verrucous carcinoma (n = 18), spindle cell carcinoma (n = 3), and basaloid cell carcinoma (n = 2). Undifferentiated carcinoma of nasopharyngeal type was located in the supraglottis or piriform sinus beneath an intact mucosa and initial endoscopic biopsy was most often negative. The discrepancy between an intact mucosa at endoscopy and a solid mass with homogenous enhancement at CT or MRI was characteristic for these tumors and warranted further investigations to obtain the definitive histologic diagnosis. Verrucous carcinoma displayed characteristic clinical, radiologic, and pathologic features, namely, an exophytic tumor arising from the glottic level displaying a rugged surface with finger-like projections but with only minor submucosal infiltration. Spindle cell carcinoma appeared as a polypoid mass with a thin stalk arising from the supraglottis. Basaloid cell carcinoma displayed a distinct lobulated enhancement pattern which was observed on contrast-enhanced T1-weighted SE images. Although the MR and CT features of atypical forms of squamous cell carcinoma cannot be considered pathognomonic they should raise the differential diagnosis even if endoscopic biopsy has been negative. The radiologist's awareness of the appearance of these unusual tumors on CT and MR images may greatly facilitate the diagnostic work-up and helps to guide the endoscopist to the adequate biopsy site in order to establish the correct diagnosis.
We evaluated the efficacy of N-Acetyl-Aspartyl-Glutamic acid (magnesium salt) (NAAGA) eye-drops i... more We evaluated the efficacy of N-Acetyl-Aspartyl-Glutamic acid (magnesium salt) (NAAGA) eye-drops in preventing the conjunctival and uveal allergic inflammation induced by reverse passive Arthus reaction in the rabbit. The permeability of the blood-conjunctival and blood-aqueous barriers was investigated by the leakage of 125I-labelled rabbit serum albumin injected intravenously prior to the challenge with the antigen. Permeability of both barriers was markedly increased 2 hours after the triggering of the allergic reaction; marked edema of the conjunctiva was also observed. Pretreatment with 1, 3, 6% (w/w) NAAGA eye-drops prevented the conjunctival inflammatory changes in a dose related manner and to a lesser degree, the breakdown of the blood-aqueous barrier. The distribution of topically applied 14C-NAAGA in the rabbit eyes was also investigated.
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Papers by G. Moulin